Media Articles Related to Ablavar (Gadofosveset)
Advances in Companion Diagnostics and Precision Medicine Congress,25-26 April 2017, London
Source: Conferences News From Medical News Today [2017.03.15]
With only a few weeks to go Oxford Global are proud to bring to you the final agenda for the Advances in Companion Diagnostics and co-located Precision Medicine Congress to be held on the 25-26...
Diagnostic Mammograms Find More Cancers, and More False-Positives
Source: MedicineNet Mammogram Specialty [2017.02.28]
Title: Diagnostic Mammograms Find More Cancers, and More False-Positives
Category: Health News
Created: 2/28/2017 12:00:00 AM
Last Editorial Review: 2/28/2017 12:00:00 AM
Advances in Companion Diagnostics Congress - Pre-Congress Live Webinars: Register For Free
Source: Conferences News From Medical News Today [2017.02.10]
Pre-Congress Live Webinars: Register For Free 'Challenges in Developing Companion Diagnostics for Cancer and Immunology'Tuesday 14th February - 3.00 pm GMTCan't make the date?
Flexible future of point-of-care disease diagnostic
Source: Bird Flu / Avian Flu News From Medical News Today [2015.07.29]
The world-wide deployment of biomedical devices for health monitoring, point-of-care diagnostics and environmental sensing is hampered by their high cost that is not readily affordable for e.g.
Parameters for the Differential Diagnosis of Hyponatraemia
Source: Medscape Critical Care Headlines [2017.04.21]
Could copeptin play a role in the differential diagnosis of hyponatremia? How does it compare with other methods of diagnostic evaluation?
Published Studies Related to Ablavar (Gadofosveset)
Contrast-enhanced whole-heart MR coronary angiography at 3.0 T using the intravascular contrast agent gadofosveset. [2009.07]
OBJECTIVES: The purpose of this study was to compare contrast-enhanced (CE) whole-heart coronary magnetic resonance angiography (MRA) at 3.0 T using gadofosveset to noncontrast-enhanced steady-state free precession (SSFP) coronary MRA at 1.5 T... CONCLUSIONS: CE whole-heart coronary MRA at 3.0 T demonstrated higher overall CNR between coronary blood and myocardium and an improved image quality of the distal coronary segments compared with noncontrast-enhanced SSFP coronary MRA at 1.5 T.
Safety and efficacy of gadofosveset-enhanced MR angiography for evaluation of pedal arterial disease: multicenter comparative phase 3 study. [2008.01]
CONCLUSION: Because of markedly better efficacy than no contrast agent and a minimal and transient side-effect profile, 0.03 mmol/kg of gadofosveset was found safe and effective for MR angiography of patients with pedal arterial disease.
Contrast-enhanced MRA of the renal and aorto-iliac-femoral arteries: comparison of gadobenate dimeglumine and gadofosveset trisodium. [2011.02]
RATIONALE AND OBJECTIVES: Dedicated contrast agents are now available for contrast-enhanced magnetic resonance angiography (CE-MRA). This study retrospectively compares the safety and diagnostic performance data from Phase III regulatory trials performed to evaluate gadobenate dimeglumine (MultiHance((R))) and gadofosveset trisodium (Vasovist(R))) for renal and peripheral CE-MRA... CONCLUSION: The diagnostic performance of CE-MRA for the detection of significant steno-occlusive disease is similar with gadofosveset and gadobenate dimeglumine although the rate of adverse events appears higher with gadofosveset. Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
CMR assessment of endothelial damage and angiogenesis in porcine coronary arteries using gadofosveset. [2011.01.26]
CONCLUSION: Contrast enhanced coronary CMR with gadofosveset can detect experimentally induced endothelial damage and angiogenesis in the porcine coronary artery wall.
Diffusion magnetic resonance imaging with gadofosveset trisodium as a negative contrast agent for lymph node metastases assessment. [2011.01]
PURPOSE: The aim of this study was to assess the feasibility of using intravenously administered gadofosveset trisodium as a negative contrast agent for lymph node (LN) assessment with diffusion-weighted imaging (DWI) using a VX2 tumor model in rabbits... CONCLUSION: The SI of metastatic LNs at DWI is less suppressed than that of nonmetastatic LNs after the intravenous administration of gadofosveset trisodium. Therefore, intravenously administered gadofosveset trisodium shows promise for use as a negative contrast agent for discriminating metastatic from nonmetastatic LNs at DWI.
Clinical Trials Related to Ablavar (Gadofosveset)
Pulmonary MR Angiography and Lower Extremity MR Venous Imaging Using Gadofosveset (Ablavar) [Completed]
The use of the contrast agent, Ablavar, will help with the diagnosis of pulmonary embolism
in magnetic resonance imaging (MRI).
Dose-varied Evaluation of Ablavar-enhanced MR Angiography of the Central Veins of the Chest in Healthy Participants [Completed]
The purpose of this study is to assess the image quality of Ablavar-enhanced MR angiography
of the central veins of the chest, and to determine whether dose reduction can be performed
while maintaining image quality. This will be a prospective randomized study, in which
healthy volunteers will be recruited to undergo a central veins magnetic resonance angiogram
(MRA). They will receive either the FDA-approved dose or a lower dose of Ablavar.
Quantitative and qualitative analysis will be performed on the images.
Prospective Evaluation of the Incidence of NSF in Patients With Kidney Disease Undergoing MR [Completed]
Phase 4, open-label, two-year, prospective, multi-center, follow-up study conducted at up 15
sites in USA. Approximately 1,000 patients with moderate-to-severe CKD will be enrolled and
followed for up to 24 months.
Gadofosveset Trisodium (Ablavar, Gdfos) in Distinguishing Hemangiomas and Metastases: A Prospective Trial [Recruiting]
Magnetic Resonance Imaging for Lymph Node Staging in Ovarian Cancer [Not yet recruiting]
Advanced epithelial ovarian cancer has high morbidity and mortality. Patients presenting
with advanced stage ovarian cancer often have cancer spread to regional lymph nodes. Imaging
strategies to depict involved lymph nodes are currently not successful. The purpose of this
study is to evaluate if magnetic resonance imaging (MRI) with gadofosveset trisodium
contrast enhancement (GDF-MRI) and diffusion weighted imaging (DW-MRI) is able to identify
involved lymph nodes in a preoperative setting. This could guide the surgeon during surgery
to dissect lymph nodes which could lead to an optimal diagnosis/staging with the lowest
possible morbidity. We want to determine the optimal imaging settings and feasibility of MRI
for the detection of pathological lymph nodes in women with advanced (FIGO stage IIB-IV)
ovarian cancer undergoing primary debulking surgery and compare this to conventional
imaging with computer tomography (CT).