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Abbokinase (Urokinase) - Published Studies


Abbokinase Related Published Studies

Well-designed clinical trials related to Abbokinase (Urokinase)

Pharmacokinetics and safety of a new bioengineered thrombolytic agent, human tissue urokinase type plasminogen activator in Chinese healthy volunteers. [2011.01]

An effective treatment for cerebral hemorrhage: minimally invasive craniopuncture combined with urokinase infusion therapy. [2010.05]

Efficacy and safety of 2-hour urokinase regime in acute pulmonary embolism: a randomized controlled trial. [2009.12.29]

[Thrombolysis of rabbit's pulmonary embolism with thrombus-targeted urokinase immune liposome] [2009.11]

Percutaneous treatment of intrabdominal abscess: urokinase versus saline serum in 100 cases using two surgical scoring systems in a randomized trial. [2009.07]

Use of urokinase in percutaneous drainage of large breast abscesses. [2009.04]

Intermittent intravenous urokinase for critical limb ischemia in diabetic foot ulceration. [2008.09]

Prevention of coagulase-negative staphylococcal central venous catheter-related infection using urokinase rinses: a randomized double-blind controlled trial in patients with hematologic malignancies. [2008.01.20]

Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan. [2007.10]

A study of loculated tuberculous pleural effusions treated with intrapleural urokinase. [2006.11]

Comparison of urokinase and video-assisted thoracoscopic surgery for treatment of childhood empyema. [2006.07.15]

[Combining exchange of cerebrospinal fluid with small dose of urokinase injection for subarachnoid hemorrhage] [2005.04]

Use of intraperitoneal urokinase for resistant bacterial peritonitis in continuous ambulatory peritoneal dialysis. [2005.03]

Comparison of intravenous and intra-arterial urokinase thrombolysis for acute ischaemic stroke. [2005.01]

Results of a multicentre, randomised controlled trial of intra-arterial urokinase in the treatment of acute posterior circulation ischaemic stroke. [2005]

The effects of urokinase instillation therapy via percutaneous transthoracic catheter in loculated tuberculous pleural effusion: a randomized prospective study. [2004.10.31]

Recombinant urokinase for restoration of patency in occluded central venous access devices. A double-blind, placebo-controlled trial. [2004.09]

Prophylactic urokinase in the management of long-term venous access devices in children: a Children's Oncology Group study. [2004.07.01]

Dose-ranging trial with a recombinant urokinase (urokinase alfa) for occluded central venous catheters in oncology patients. [2004.06]

Effects of co-administration of urokinase and benazepril on severe IgA nephropathy. [2004.04]

Natural saline-flush is sufficient to maintain patency of immobilized-urokinase double-lumen catheter used to provide temporary blood access for hemodialysis. [2004]

Effect on cerebral vasospasm of coil embolization followed by microcatheter intrathecal urokinase infusion into the cisterna magna: a prospective randomized study. [2003.11]

Selection of acute ischemic stroke patients for intra-arterial thrombolysis with pro-urokinase by using ASPECTS. [2003.08]

A prospective double-blind randomized trial of urokinase flushes to prevent bacteremia resulting from luminal colonization of subcutaneous central venous catheters. [2002.12]

External pneumatic compression does not increase urokinase plasminogen activator after abdominal surgery. [2002.11]

Randomised trial of intrapleural urokinase in the treatment of childhood empyema. [2002.04]

Recombinant tissue plasminogen activator versus urokinase for local thrombolysis of femoropopliteal occlusions: a prospective, randomized multicenter trial. [2001.12]

Intrapleural urokinase in the management of parapneumonic empyema: a randomised controlled trial. [2001.12]

Lack of efficacy of twice-weekly urokinase in the prevention of complications associated with Hickman catheters: a multicentre randomised comparison of urokinase versus heparin. [2001.12]

Peripheral artery occlusion: treatment with abciximab plus urokinase versus with urokinase alone--a randomized pilot trial (the PROMPT Study). Platelet Receptor Antibodies in Order to Manage Peripheral Artery Thrombosis. [2001.12]

Thrombosed hemodialysis grafts: lyse and wait with tissue plasminogen activator or urokinase compared to mechanical thrombolysis with the Arrow-Trerotola Percutaneous Thrombolytic Device. [2001.10]

Economic assessment of rheolytic thrombectomy versus intracoronary urokinase for treatment of extensive intracoronary thrombus: Results from a randomized clinical trial. [2001.10]

A randomized trial confirming the efficacy of reduced dose recombinant tissue plasminogen activator in a Chinese myocardial infarction population and demonstrating superiority to usual dose urokinase: the TUCC trial. [2001.08]

Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1. [2001.06.20]

[Study on effect of shenmai injection in protecting myocardium against ischemia-reperfusion injury in thrombolytic therapy with urokinase for acute myocardial infarction patients evaluated by 99mTc-MIBI myocardial imaging] [2001.02]

[The study of intrapleural urokinase in the prevention of pleural thickening and loculated effusions by tuberculous pleurisy] [2001.01]

Pulmonary embolism from pulse-spray pharmacomechanical thrombolysis of clotted hemodialysis grafts: urokinase versus heparinized saline. [2000.10]

Percutaneous fibrin sheath stripping versus transcatheter urokinase infusion for malfunctioning well-positioned tunneled central venous dialysis catheters: a prospective, randomized trial. [2000.10]

Intracavitary urokinase for enhancement of percutaneous abscess drainage: phase II trial. [2000.06]

Treatment of intraventricular hemorrhage with urokinase : effects on 30-Day survival. [2000.04]

Role of intraperitoneal urokinase in acute peritonitis and prevention of catheter loss in peritoneal dialysis patients. [2000]

Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. [1999.12.01]

Weekly prophylactic urokinase instillation in tunneled central venous access devices. [1999.11]

Localization and significance of urokinase plasminogen activator and its receptor in placental tissue from intrauterine, ectopic and molar pregnancies. [1999.11]

Randomized clinical trial of urokinase versus heparin in unstable angina. [1999.10]

Prourokinase versus urokinase for recanalization of peripheral occlusions, safety and efficacy: the PURPOSE trial. [1999.09]

Inactivation of single-chain urokinase-type plasminogen activator by thrombin in human subjects. [1999.08]

Low- versus high-dose recombinant urokinase for the treatment of chronic saphenous vein graft occlusion. [1999.06.15]

Streptokinase and urokinase for the treatment of pleural effusions and empyemas. [1999.04]

A comparative study on the effects of low dose of tPA and different regimens of intravenous urokinase in acute myocardial infarction. [1999.01]

Intrapleural urokinase versus normal saline in the treatment of complicated parapneumonic effusions and empyema. A randomized, double-blind study. [1999.01]

Comparison of double bolus urokinase versus front-loaded alteplase regimen for acute myocardial infarction. Thrombolysis in Myocardial Infarction in Korea (TIMIKO) study group. [1998.09.15]

Comparative results of thrombolysis treatment with rt-PA and urokinase: a pilot study. [1998.08]

A cohort study of the safety and feasibility of intraventricular urokinase for nonaneurysmal spontaneous intraventricular hemorrhage. [1998.08]

A study on the efficacy of intraventricular urokinase in the treatment of intraventricular haemorrhage. [1998.06]

A prospective randomized trial of urokinase as an adjuvant in the treatment of proven Hickman catheter sepsis. [1998.05]

A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators. [1998.04.16]

Dialysis access graft thrombolysis: randomized study of pulse-spray versus continuous urokinase infusion. [1998.03]

PROACT: a phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke. PROACT Investigators. Prolyse in Acute Cerebral Thromboembolism. [1998.01]

Low-dose urokinase infusions to treat fibrinous obstruction of venous access devices in cancer patients. [1997.07]

Intrapleural streptokinase versus urokinase in the treatment of complicated parapneumonic effusions: a prospective, double-blind study. [1997.01]

Hemostatic changes after thrombolytic therapy with saruplase (unglycosylated single-chain urokinase-type plasminogen activator) and urokinase (two-chain urokinase-type plasminogen activator). [1996.11]

Bolus recombinant urokinase versus heparin in deep venous thrombosis: a randomized controlled trial. [1996.08]

Comparison of streptokinase and urokinase in local thrombolysis of peripheral arterial occlusions for lower limb salvage. [1996.07]

Adjunctive intracoronary urokinase therapy during percutaneous transluminal coronary angioplasty. [1996.06.01]

Urokinase plasminogen activator, a strong independent prognostic factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay. [1996.05]

Comparison of tissue plasminogen activator and urokinase in the local infiltration thrombolysis of peripheral arterial occlusions. [1996.05]

Prospective, randomized trial of prolonged intracoronary urokinase infusion for chronic total occlusions in native coronary arteries. [1996.05]

Long-term intermittent urokinase therapy in patients with end-stage coronary artery disease and refractory angina pectoris: a randomized dose-response trial. [1996.03.01]

A placebo-controlled study on urokinase therapy in systemic sclerosis. [1996]

Clinical studies with the new glycosylated recombinant prourokinase. [1995.11]

Thrombolysis with recombinant unglycosylated single-chain urokinase-type plasminogen activator (saruplase) in acute myocardial infarction: influence of heparin on early patency rate (LIMITS study). Liquemin in Myocardial Infarction During Thrombolysis With Saruplase. [1995.08]

Protection of single-chain urokinase-type plasminogen activator (scu-PA) in aprotinin treated cardiac surgical patients undergoing cardiopulmonary bypass. [1995.05]

Treatment of severe intraventricular hemorrhage by intraventricular infusion of urokinase. [1995]

New recombinant glycosylated prourokinase for treatment of patients with acute myocardial infarction. Prourokinase Study Group. [1994.11.01]

Urokinase versus recombinant tissue plasminogen activator in thrombosed central venous catheters: a double-blinded, randomized trial. [1994.10]

A prospective randomized double-blind trial of bolus urokinase in the treatment of established Hickman catheter sepsis in children. [1994.06]

Treatment of resistant peritonitis in continuous ambulatory peritoneal dialysis with intraperitoneal urokinase: a double-blind clinical trial. [1994]

Comparison of intrathecal administration of urokinase and tissue plasminogen activator on subarachnoid clot and chronic vasospasm in a primate model. [1993.10]

A prospective, randomized, blinded, and placebo-controlled trial of intraoperative intra-arterial urokinase infusion during lower extremity revascularization. Regional and systemic effects. [1993.10]

Pharmacokinetics of saruplase, a recombinant unglycosylated human single-chain urokinase-type plasminogen activator and its effects on fibrinolytic and haemostatic parameters in healthy male subjects. [1993.08.02]

Multicenter dose-finding trial for thrombolysis with urokinase preactivated pro-urokinase (TCL 598) in acute myocardial infarction. German Preactivated Pro-Urokinase Study Group. [1992.07]

Recombinant tissue-type plasminogen activator versus a novel dosing regimen of urokinase in acute pulmonary embolism: a randomized controlled multicenter trial. [1992.07]

Effects of intravenous urokinase versus alteplase on total pulmonary resistance in acute massive pulmonary embolism: a European multicenter double-blind trial. The European Cooperative Study Group for Pulmonary Embolism. [1992.02]

Comparison of intravenous urokinase plus heparin versus heparin alone in acute myocardial infarction. Urochinasi per via Sistemica nell'Infarto Miocardico (USIM) Collaborative Group. [1991.09.01]

Effects of urokinase and heparin on minimal cross-sectional area of the culprit narrowing in unstable angina pectoris. [1991.08.15]

[A study of a systemic fibrinolytic treatment of acute myocardial infarction. The effect of a moderate dose infusion of urokinase] [1991.08]

Effect of urokinase on preservation of renal function in patients with diabetic nephropathy. [1991.04]

Two urokinase dose regimens in native arterial and graft occlusions: initial results of a prospective, randomized clinical trial. [1991.03]

Intravenous recombinant tissue-type plasminogen activator (rt-PA) and urokinase (UK) in patients with evolving myocardial infarction--a multicenter double-blind, randomized trial in Japan. [1991.03]

The first international urokinase/warfarin trial in colorectal cancer. [1991.01]

Effect of intra-arterial tissue plasminogen activator and urokinase on autologous arterial emboli in the cerebral circulation of rabbits [corrected] [1990.11]

Coronary reperfusion studies with pro-urokinase in acute myocardial infarction: evidence for synergism of low dose urokinase. [1990.09]

Recombinant tissue-type plasminogen activator versus urokinase in peripheral arterial and graft occlusions: a randomized trial. [1990.04]

Adjuvant portal liver infusion in colorectal cancer with 5-fluorouracil/heparin versus urokinase versus control. Results of a prospective randomized clinical trial (colorectal adenocarcinoma trial I). [1990.02.01]

Urokinase plus heparin versus aspirin in unstable angina and non-Q-wave myocardial infarction. [1989.10.15]

DDAVP induces systemic release of urokinase-type plasminogen activator. [1989.09.29]

Tenckhoff catheter replacement or intraperitoneal urokinase: a randomised trial in the management of recurrent continuous ambulatory peritoneal dialysis (CAPD) peritonitis. [1989]

Randomized, double-blinded multicenter study. Comparison of intracoronary single-chain urokinase-type plasminogen activator, pro-urokinase (GE-0943), and intracoronary urokinase in patients with acute myocardial infarction. [1988.10]

Intravenous recombinant tissue plasminogen activator (rt-PA) and urokinase in acute myocardial infarction: results of the German Activator Urokinase Study (GAUS). [1988.09]

Randomised controlled trial of recombinant tissue plasminogen activator versus urokinase in the treatment of acute pulmonary embolism. [1988.08.06]

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