Abbokinase (Urokinase) - Summary

ABBOKINASE SUMMARY

Abbokinase® (urokinase) is a thrombolytic agent obtained from human neonatal kidney cells grown in tissue culture.

Abbokinase® is indicated in adults:

• For the lysis of acute massive pulmonary emboli, defined as obstruction of blood flow to a lobe or multiple segments.
• For the lysis of pulmonary emboli accompanied by unstable hemodynamics, i.e., failure to maintain blood pressure without supportive measures.

The diagnosis should be confirmed by objective means, such as pulmonary angiography or non-invasive procedures such as lung scanning.

ABBOKINASE NEWS HIGHLIGHTS

Media Articles Related to Abbokinase (Urokinase)

APTA Supports Surgeon General's "Call To Action" To Prevent Deep Vein Thrombosis And Pulmonary Embolism
Source: Rehabilitation / Physical Therapy News From Medical News Today [2008.09.30]

Pulmonary Embolism (Blood Clot in the Lung)
Source: MedicineNet Homocysteine Specialty [2008.04.18]

Belt And Braces Approach May Prevent Deep Vein Thromboses
Source: Blood / Hematology News From Medical News Today [2008.10.08]

Bayer's Novel Oral Anticoagulant Xarelto(R) (Rivaroxaban) Gets European Licence
Source: Blood / Hematology News From Medical News Today [2008.10.03]

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Published Studies Related to Abbokinase (Urokinase)

Prevention of coagulase-negative staphylococcal central venous catheter-related infection using urokinase rinses: a randomized double-blind controlled trial in patients with hematologic malignancies. [2008.01.20]

Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan. [2007.10]

A study of loculated tuberculous pleural effusions treated with intrapleural urokinase. [2006.11]

Comparison of urokinase and video-assisted thoracoscopic surgery for treatment of childhood empyema. [2006.07.15]

[Combining exchange of cerebrospinal fluid with small dose of urokinase injection for subarachnoid hemorrhage] [2005.04]

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Clinical Trials Related to Abbokinase (Urokinase)

Urokinase Therapy in Diabetic Foot Syndrome [Completed]

Dornase Alfa and Urokinase for Kids With Pleural Empyema [Recruiting]

Urokinase Plasminogen Activator System in Benign Prostatic Hyperplasia [Active, not recruiting]

Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema [Completed]

A Randomized Evaluation of the Effect of Routine Normal Saline Flush Versus Heparinized Saline Solution in Groshong and Groshong PICC Catheters [Completed]

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