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Index of reports
> Cases resulting in a serious event (23)
Below is the selection of adverse event reports related to Zolinza (Vorinostat) that includes cases resulting in a serious event.
Adverse event in 61 year old female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-10-31
Patient: 61 year old female, weighing 80.4 kg (176.9 pounds)
Adverse reactions / side effects: Prothrombin Time Shortened, Pulmonary Embolism, Activated Partial Thromboplastin Time Shortened, Thrombocytopenia, Deep Vein Thrombosis
Suspect drug(s):
Zolinza
Dosage: 400 mg daily 21 of 28 days p.o. 30 mg daily 21 day of 28 days po
Administration route: Oral
Indication: Breast Cancer Metastatic
Start date: 2007-05-04
End date: 2007-05-24
Zolinza
Dosage: 400 mg daily 21 of 28 days p.o. 30 mg daily 21 day of 28 days po
Administration route: Oral
Indication: Breast Cancer Metastatic
Start date: 2007-06-01
End date: 2007-10-24
Other drugs received by patient: Tamoxifen Citrate; Zometa; Glucosamine Chondroitin
Adverse event in 68 year old female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-10-19
Patient: 68 year old female
Adverse reactions / side effects: Abdominal Discomfort, Osteonecrosis, Fatigue
Suspect drug(s):
Zolinza (Vorinostat)
Adverse event in 55 year old male receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-10-16
Patient: 55 year old male
Adverse reactions / side effects: Hypoventilation, Anaemia, Delirium, Malaise, Fungal Infection, Dehydration, Thrombocytopenia, Acute Prerenal Failure
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zolinza (Vorinostat)
Adverse event in 60 year old male receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-10-15
Patient: 60 year old male
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Coagulopathy, Drug Interaction, Pyrexia, Myalgia, Nephrolithiasis, Pyelectasia, Oedema Peripheral, Muscle Spasms, Cough, Back Pain, Haemorrhage Urinary Tract, Haematuria, Anaemia, Benign Prostatic Hyperplasia, Renal Cyst, Flank Pain, Dehydration
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Coumadin
Administration route: Oral
End date: 2007-07-25
Lipitor
Administration route: Oral
Indication: Hyperlipidaemia
End date: 2007-07-25
Targretin
Administration route: Oral
End date: 2007-07-25
Zolinza
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2007-07-13
End date: 2007-07-25
Other drugs received by patient: Paxil; Ritalin; Megace; Synthroid; Toprol-XL; Omega-3 Marine Triglycerides; Prinivil; Zantac; Hydroxyzine Hydrochloride
Adverse event in male receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-10-05
Patient: male
Adverse reactions / side effects: Mycosis Fungoides
Adverse event resulted in: death
Suspect drug(s):
Zolinza (Vorinostat)
Adverse event in 53 year old female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-10-04
Patient: 53 year old female, weighing 77.0 kg (169.4 pounds)
Adverse reactions / side effects: Mucosal Inflammation, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased, non-Hodgkin's Lymphoma
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Zolinza
Administration route: Oral
Indication: non-Hodgkin's Lymphoma
Start date: 2007-03-14
End date: 2007-03-19
Zolinza
Administration route: Oral
Start date: 2007-03-21
End date: 2007-03-26
Zolinza
Administration route: Oral
Start date: 2007-04-13
End date: 2007-04-25
Zolinza
Administration route: Oral
Start date: 2007-04-26
End date: 2007-04-29
Zolinza
Administration route: Oral
Start date: 2007-05-02
End date: 2007-05-14
Other drugs received by patient: Cytoxan; Nexavar; Prednisone; Buphenyl; Rituxan
Adverse event in 72 year old male receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-10-03
Patient: 72 year old male
Adverse reactions / side effects: Weight Decreased, Nausea, Feeling Cold, Malaise, Fatigue, Dehydration, Anorexia, Malignant Melanoma, Dizziness
Suspect drug(s):
Zolinza
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2007-05-18
End date: 2007-07-05
Zolinza
Administration route: Oral
Start date: 2007-07-05
End date: 2007-07-21
Other drugs received by patient: Celebrex; Cyclobenzaprine Hydrochloride
Adverse event in 63 year old female receiving Zolinza (Vorinostat)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-03
Patient: 63 year old female, weighing 76.5 kg (168.3 pounds)
Adverse reactions / side effects: Back Pain, Hypotension, Atrial Fibrillation, Dizziness, Platelet Count Decreased, Pulmonary Artery Thrombosis
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zolinza (Vorinostat)
Other drugs received by patient: Tamoxifen Citrate; Compasine; Oxicodone; Aciphex
Adverse event in 50 year old male receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-07-30
Patient: 50 year old male
Adverse reactions / side effects: Drug Level Increased, Drug Interaction
Suspect drug(s):
Cyclosporine
Zolinza
Administration route: Oral
Start date: 2007-06-01
Adverse event in 84 year old female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-07-30
Patient: 84 year old female
Adverse reactions / side effects: Fatigue, Diarrhoea, Mycosis Fungoides, Platelet Count Decreased
Suspect drug(s):
Zolinza (Vorinostat)
Adverse event in 80 year old male receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-07-25
Patient: 80 year old male
Adverse reactions / side effects: Malignant Melanoma
Suspect drug(s):
Zolinza (Vorinostat)
Adverse event in 79 year old female receiving Zolinza (Vorinostat)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-07-10
Patient: 79 year old female, weighing 48.0 kg (105.6 pounds)
Adverse reactions / side effects: Weight Decreased, Chest Discomfort, Dyspnoea, Vomiting, Restlessness, Nausea, Muscular Weakness, Constipation, Discomfort, Drug Toxicity, Fatigue, Flank Pain, Anorexia, Oedema Peripheral, Cold Sweat, Heart Rate Abnormal
Suspect drug(s):
Zolinza
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2007-04-10
End date: 2007-04-15
Zolinza
Administration route: Oral
Start date: 2007-04-17
Zolinza
Administration route: Oral
Start date: 2007-04-03
Other drugs received by patient: Boniva; Digoxin; Ranitidine; Metformin; Norvasc; Lipitor; Tricor; Hydroxyzine Hydrochloride; Synthroid; Clobetasol Propionate; Triamcinolone; Fluocinolone Acetonide; Vitamin E; Ascorbic Acid; Calcium (Unspecified); Docusate Sodium; Compazine
Adverse event in 69 year old female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-06-20
Patient: 69 year old female, weighing 70.0 kg (154.0 pounds)
Adverse reactions / side effects: Weight Decreased, Anaemia, Mycosis Fungoides, Hepatitis B Positive, Transaminases Increased, Syncope, Anorexia, Dehydration, Hepatitis A Antibody Positive, Dizziness, Transient Ischaemic Attack, Hepatitis C Positive, Acute Prerenal Failure
Adverse event resulted in: hospitalization
Suspect drug(s):
Zolinza
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2007-02-02
End date: 2007-03-01
Zolinza
Administration route: Oral
Start date: 2007-05-04
End date: 2007-05-05
Zolinza
Administration route: Oral
Start date: 2007-03-02
End date: 2007-04-20
Zolinza
Administration route: Oral
Start date: 2006-12-22
Adverse event in 69 year old female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-06-06
Patient: 69 year old female, weighing 70.0 kg (154.0 pounds)
Adverse reactions / side effects: Weight Decreased, Anaemia, Mycosis Fungoides, Hepatitis B Positive, Transaminases Increased, Syncope, Anorexia, Dehydration, Hepatitis A Antibody Positive, Transient Ischaemic Attack, Hepatitis C Positive, Acute Prerenal Failure
Adverse event resulted in: hospitalization
Suspect drug(s):
Zolinza
Administration route: Oral
Indication: Mycosis Fungoides
Start date: 2007-02-02
End date: 2007-03-01
Zolinza
Administration route: Oral
Start date: 2007-05-04
End date: 2007-05-05
Zolinza
Administration route: Oral
Start date: 2007-03-02
End date: 2007-04-20
Zolinza
Administration route: Oral
Start date: 2006-12-22
Adverse event in female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-05-23
Patient: female
Adverse reactions / side effects: Mycosis Fungoides, Anorexia
Suspect drug(s):
Zolinza (Vorinostat)
Other drugs received by patient: Corticosteroids (Unspecified); [therapy Unspecified]
Adverse event in 78 year old female receiving Zolinza (Vorinostat)
Reported by a individual with unspecified qualification from United States on 2007-05-10
Patient: 78 year old female
Adverse reactions / side effects: Dysgeusia, Weight Decreased, Pruritus, Drug Ineffective, Nausea, RED Blood Cell Count Increased, Platelet Count Decreased
Suspect drug(s):
Compazine
Kytril
Zolinza
Dosage: see image
Administration route: Oral
Indication: T-Cell Lymphoma
Start date: 2006-11-30
End date: 2007-01-19
Zolinza
Dosage: see image
Administration route: Oral
Indication: T-Cell Lymphoma
Start date: 2007-02-01
Other drugs received by patient: Levothyroxine Sodium
Adverse event in male receiving Zolinza (Vorinostat)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-05-09
Patient: male
Adverse reactions / side effects: Death, Adverse Event
Adverse event resulted in: death
Suspect drug(s):
Zolinza (Vorinostat)
Adverse event in 60 year old female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-04-06
Patient: 60 year old female
Adverse reactions / side effects: Renal Failure, Diarrhoea, Dehydration, Myocardial Infarction
Adverse event resulted in: death, life threatening event, disablity
Suspect drug(s):
Zolinza
Administration route: Oral
Indication: Mycosis Fungoides Refractory
Start date: 2006-11-01
End date: 2006-01-01
Zolinza
Administration route: Oral
Zolinza
Administration route: Oral
Start date: 2006-01-01
End date: 2006-12-01
Adverse event in 71 year old male receiving Zolinza (Vorinostat)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-03-27
Patient: 71 year old male
Adverse reactions / side effects: Confusional State, Blood Potassium Decreased, Mycosis Fungoides, Pain, Pyrexia
Adverse event resulted in: hospitalization
Suspect drug(s):
Zolinza (Vorinostat)
Other drugs received by patient: Oxycodone; Temazepam; Hydrochlorothiazide and Triamterene; Bactroban; Norvasc; Bentyl; Xanax; Vitamins (Unspecified); Vistaril
Adverse event in male receiving Zolinza (Vorinostat)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-03-13
Patient: male
Adverse reactions / side effects: Death, Thrombolysis
Adverse event resulted in: death
Suspect drug(s):
Zolinza (Vorinostat)
Adverse event in 71 year old male receiving Zolinza (Vorinostat)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-03-12
Patient: 71 year old male
Adverse reactions / side effects: Pain, Mycosis Fungoides
Suspect drug(s):
Zolinza (Vorinostat)
Other drugs received by patient: Oxycodone; Temazepam; Hydrochlorothiazide and Triamterene; Bactroban; Norvasc; Bentyl; Xanax; Vitamins (Unspecified); Vistaril
Adverse event in 60 year old female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-01-29
Patient: 60 year old female
Adverse reactions / side effects: Diarrhoea, Dehydration, Myocardial Infarction
Adverse event resulted in: death
Suspect drug(s):
Zolinza (Vorinostat)
Adverse event in female receiving Zolinza (Vorinostat)
Reported by a physician from United States on 2007-01-11
Patient: female
Adverse reactions / side effects: Diarrhoea, Dehydration, Myocardial Infarction
Adverse event resulted in: death
Suspect drug(s):
Zolinza (Vorinostat)
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