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Index of reports
> Cases resulting in other serious reactions (214)
> Cases with Blood Creatine Phosphokinase Increased (19)
Below is the selection of adverse event reports related to Zocor (Simvastatin) that includes cases resulting in other serious reactions where reactions include blood creatine phosphokinase increased.
Adverse event in 76 year old receiving Zocor (Simvastatin)
Reported by a physician from Australia on 2007-10-24
Patient: 76 year old
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Muscular Weakness, Myopathy, Renal Failure Acute
Adverse event resulted in: hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Zocor
Administration route: Oral
Start date: 2005-01-01
End date: 2006-01-01
Adverse event in 54 year old male receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-07-06
Patient: 54 year old male
Adverse reactions / side effects: Muscle Necrosis, Blood Creatine Phosphokinase Increased, Pain in Extremity, Abasia, Oedema Peripheral, Compartment Syndrome, Tenderness
Adverse event resulted in: hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Blood Cholesterol Increased
Levothyroxine Sodium
Indication: Hypothyroidism
Adverse event in 73 year old male receiving Zocor (Simvastatin)
Reported by a physician from Sweden on 2007-06-20
Patient: 73 year old male
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Muscle Atrophy, Rhabdomyolysis, Pain in Extremity, Abasia, Polyneuropathy, Dysstasia, Peroneal Nerve Palsy, Amyotrophic Lateral Sclerosis, Chest Pain, Electromyogram Abnormal, Asthenia
Adverse event resulted in: disablity
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Blood Cholesterol Increased
Start date: 1999-01-01
End date: 2000-01-01
Zocor
Administration route: Oral
Start date: 2000-01-01
Other drugs received by patient: Hydrodiuril
Adverse event in 76 year old receiving Zocor (Simvastatin)
Reported by a physician from Australia on 2007-05-17
Patient: 76 year old
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Myopathy, Renal Failure Acute
Suspect drug(s):
Zocor
Administration route: Oral
Zocor
Administration route: Oral
Adverse event in 16 year old female receiving Zocor (Simvastatin)
Reported by a individual with unspecified qualification from Italy on 2007-04-20
Patient: 16 year old female, weighing 51.7 kg (113.8 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Blood Thyroid Stimulating Hormone Increased, Varicella
Suspect drug(s):
Zetia
Dosage: 10 mg/daily/po
Administration route: Oral
Start date: 2006-09-27
End date: 2007-02-13
Zocor
Dosage: 10 mg/daily/po
Administration route: Oral
Start date: 2006-09-27
End date: 2007-02-13
Adverse event in 54 year old male receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-04-20
Patient: 54 year old male
Adverse reactions / side effects: Muscle Necrosis, Blood Creatine Phosphokinase Increased, Compartment Syndrome
Adverse event resulted in: hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Blood Cholesterol Increased
Levothyroxine Sodium
Indication: Hypothyroidism
Adverse event in 19 year old female receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-04-17
Patient: 19 year old female
Adverse reactions / side effects: Myositis, Blood Creatine Phosphokinase Increased, Aspartate Aminotransferase Increased, Blood Lactate Dehydrogenase Increased
Suspect drug(s):
Zocor (Simvastatin)
Adverse event in 54 year old male receiving Zocor (Simvastatin)
Reported by a physician from United Kingdom on 2007-04-13
Patient: 54 year old male
Adverse reactions / side effects: Muscle Necrosis, Blood Creatine Phosphokinase Increased, Compartment Syndrome
Suspect drug(s):
Zocor (Simvastatin)
Other drugs received by patient: Levothyroxine Sodium
Adverse event in 54 year old male receiving Zocor (Simvastatin)
Reported by a physician from United Kingdom on 2007-04-11
Patient: 54 year old male
Adverse reactions / side effects: Muscle Necrosis, Blood Creatine Phosphokinase Increased, Compartment Syndrome
Suspect drug(s):
Zocor (Simvastatin)
Other drugs received by patient: Levothyroxine Sodium
Adverse event in 66 year old male receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-03-29
Patient: 66 year old male
Adverse reactions / side effects: Myositis, Blood Creatine Phosphokinase Increased
Suspect drug(s):
Zocor (Simvastatin)
Other drugs received by patient: Aspirin; Beclomethasone Dipropionate; Salmeterol Xinafoate; Telmisartan; Tramadol Hydrochloride
Adverse event in 16 year old female receiving Zocor (Simvastatin)
Reported by a individual with unspecified qualification from Italy on 2007-03-26
Patient: 16 year old female, weighing 61.7 kg (135.7 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Blood Thyroid Stimulating Hormone Increased, Varicella
Suspect drug(s):
Zetia
Dosage: 10 mg/daily/po
Administration route: Oral
Indication: Type IIA Hyperlipidaemia
Start date: 2006-09-27
End date: 2007-02-13
Zocor
Dosage: 10 mg/daily/po
Administration route: Oral
Indication: Type IIA Hyperlipidaemia
Start date: 2006-09-27
End date: 2007-02-13
Adverse event in 78 year old female receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-03-21
Patient: 78 year old female, weighing 70.0 kg (154.0 pounds)
Adverse reactions / side effects: Paraparesis, Fatigue, Blood Creatine Phosphokinase Increased, Rhabdomyolysis, Sensation of Heaviness, Drug Interaction, Gait Disturbance, Asthenia, Myopathy
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Hypercholesterolaemia
Start date: 2005-08-01
End date: 2007-01-30
Fusidic Acid
Administration route: Oral
Indication: Surgery
Start date: 2007-01-01
End date: 2007-01-30
Other drugs received by patient: Bendroflumethiazide; Dihydrocodeine; Ranitidine; Verapamil
Adverse event in 16 year old female receiving Zocor (Simvastatin)
Reported by a individual with unspecified qualification from Italy on 2007-03-14
Patient: 16 year old female, weighing 61.7 kg (135.7 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Blood Thyroid Stimulating Hormone Increased
Suspect drug(s):
Zetia
Dosage: 10 mg/daily/po
Administration route: Oral
Start date: 2006-09-27
End date: 2007-02-13
Zocor
Dosage: 10 mg/daily/po
Administration route: Oral
Start date: 2006-09-27
End date: 2007-02-13
Adverse event in 16 year old female receiving Zocor (Simvastatin)
Reported by a individual with unspecified qualification from United States on 2007-03-14
Patient: 16 year old female, weighing 61.7 kg (135.7 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Blood Thyroid Stimulating Hormone Increased
Suspect drug(s):
Zetia
Dosage: 10 mg/daily/po
Administration route: Oral
Start date: 2007-02-08
End date: 2007-02-13
Zocor
Dosage: 40 mg/daily/po
Administration route: Oral
Start date: 2006-02-08
End date: 2006-02-13
Adverse event in 71 year old female receiving Zocor (Simvastatin)
Reported by a physician from United States on 2007-03-07
Patient: 71 year old female
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Hepatic Enzyme Increased
Suspect drug(s):
Cyclosporine
Zocor
Adverse event in 16 year old female receiving Zocor (Simvastatin)
Reported by a individual with unspecified qualification from Italy on 2007-03-05
Patient: 16 year old female
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Blood Thyroid Stimulating Hormone Increased
Suspect drug(s):
Zetia
Dosage: 10 mg/daily
Administration route: Oral
Indication: Type IIA Hyperlipidaemia
Start date: 2007-02-08
End date: 2007-02-13
Zocor
Dosage: 40 mg/daily
Administration route: Oral
Indication: Type IIA Hyperlipidaemia
Start date: 2006-02-06
End date: 2006-02-13
Adverse event in 78 year old female receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-02-22
Patient: 78 year old female, weighing 70.0 kg (154.0 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Drug Interaction, Myopathy
Adverse event resulted in: life threatening event
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Hypercholesterolaemia
Start date: 2005-08-01
End date: 2007-01-30
Fusidic Acid
Administration route: Oral
Indication: Surgery
Start date: 2007-01-01
End date: 2007-01-30
Other drugs received by patient: Bendroflumethiazide; Dihydrocodeine; Ranitidine; Verapamil
Adverse event in male receiving Zocor (Simvastatin)
Reported by a physician from United States on 2007-01-30
Patient: male, weighing 122.0 kg (268.4 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased, Condition Aggravated
Suspect drug(s):
Zocor (Simvastatin)
Adverse event in 48 year old female receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from France on 2007-01-18
Patient: 48 year old female, weighing 55.0 kg (121.0 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Rhabdomyolysis, Drug Interaction
Adverse event resulted in: hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Hypercholesterolaemia
Start date: 2003-02-12
End date: 2006-07-20
Lopinavir and Ritonavir
Administration route: Oral
Indication: HIV Infection
Start date: 2006-06-22
Other drugs received by patient: Emtricitabine and Tenofovir Disoproxil Fumarate; Nicardipine Hydrochloride; Perindopril; Atenolol; Insulin
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