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Index of reports
> Cases resulting in life threatening events (43)
> Cases with Rhabdomyolysis (15)
Below is the selection of adverse event reports related to Zocor (Simvastatin) that includes cases resulting in life threatening events where reactions include rhabdomyolysis.
Adverse event in 73 year old male receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-01
Patient: 73 year old male, weighing 60.0 kg (132.0 pounds)
Adverse reactions / side effects: PH Urine Increased, Rhabdomyolysis, Renal Failure
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zocor (Simvastatin)
Other drugs received by patient: Allopurinol; Aspirin; Atenolol; Doxazosin Mesylate; Ferrous Sulfate; Nitroglycerin; Lansoprazole; Nifedipine; Acetaminophen; Penicillin V
Adverse event in 74 year old male receiving Zocor (Simvastatin)
Reported by a physician from Denmark on 2007-07-30
Patient: 74 year old male, weighing 67.0 kg (147.4 pounds)
Adverse reactions / side effects: Rhabdomyolysis, Dialysis, Drug Interaction, Urosepsis, Hypertension, Renal Failure Acute, Infarction
Adverse event resulted in: life threatening event
Suspect drug(s):
Zocor
Administration route: Oral
End date: 2007-06-12
Itraconazole
Administration route: Oral
Start date: 2007-06-05
End date: 2007-06-11
Adverse event in 74 year old male receiving Zocor (Simvastatin)
Reported by a physician from Denmark on 2007-07-27
Patient: 74 year old male, weighing 67.0 kg (147.4 pounds)
Adverse reactions / side effects: Rhabdomyolysis, Renal Failure Acute
Adverse event resulted in: life threatening event
Suspect drug(s):
Zocor
Administration route: Oral
Itraconazole
Administration route: Oral
Start date: 2007-06-05
End date: 2007-06-11
Adverse event in 54 year old female receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-07-20
Patient: 54 year old female
Adverse reactions / side effects: Myalgia, Rhabdomyolysis, Angioedema
Adverse event resulted in: life threatening event, disablity
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Blood Cholesterol Increased
Start date: 2007-05-01
End date: 2007-06-12
Amitriptyline Hydrochloride
Indication: Pain
Amitriptyline Hydrochloride
Indication: Sleep Disorder
Ascorbic Acid and Vitamin B Complex
Indication: Vitamin Supplementation
Ubidecarenone
Atropine Sulfate and Diphenoxylate Hydrochloride
Indication: Irritable Bowel Syndrome
Atropine Sulfate and Diphenoxylate Hydrochloride
Indication: Pain
Acetaminophen and Propoxyphene Hydrochloride
Indication: Analgesia
Furosemide
Indication: Fluid Retention
Ginger
Hydroxocobalamin
Indication: Vitamin B12 Deficiency
Magnesium (Unspecified)
Indication: Chronic Fatigue Syndrome
Vitamins (Unspecified)
Indication: Vitamin Supplementation
Acetaminophen
Indication: Analgesia
Selenium (Unspecified)
Indication: Medical Diet
Albuterol
Indication: Asthma
Niacinamide
Vitamin E
Zinc (Unspecified)
Indication: Medical Diet
Cetyl Myristoleate and Cetylated Fatty Acids
Glucametacin
Ascorbic Acid
Omega-3 Marine Triglycerides
Indication: Arthralgia
Adverse event in 76 year old male receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-06-07
Patient: 76 year old male
Adverse reactions / side effects: Rhabdomyolysis
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zetia
Administration route: Oral
Indication: Hypercholesterolaemia
Start date: 2007-04-01
End date: 2007-04-01
Zocor
End date: 2007-04-01
Lopid
End date: 2007-04-01
Other drugs received by patient: Amiodarone; Lasix; [therapy Unspecified]; Zestril
Adverse event in female receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-05-29
Patient: female, weighing 150.0 kg (330.0 pounds)
Adverse reactions / side effects: Rhabdomyolysis, Skin Ulcer, Sepsis, Chronic Obstructive Pulmonary Disease, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization, disablity
Suspect drug(s):
Zocor
Administration route: Oral
Erythromycin
Administration route: Oral
Start date: 2006-03-25
End date: 2006-04-03
Other drugs received by patient: Amitriptyline Hydrochloride; Bumetanide; Dihydrocodeine; Lisinopril; Metformin; Rosiglitazone Maleate; Levothyroxine Sodium
Adverse event in 64 year old receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from Denmark on 2007-05-08
Patient: 64 year old
Adverse reactions / side effects: Rhabdomyolysis, Drug Interaction
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Blood Cholesterol Increased
Start date: 2006-04-24
End date: 2006-11-01
Citalopram Hydrobromide
Administration route: Oral
Indication: Depression
Start date: 2006-04-24
End date: 2006-09-15
Citalopram Hydrobromide
Administration route: Oral
Start date: 2006-09-15
End date: 2006-11-01
Adverse event in 84 year old male receiving Zocor (Simvastatin)
Reported by a individual with unspecified qualification from United States on 2007-04-27
Patient: 84 year old male
Adverse reactions / side effects: Myoglobinuria, Hepatic Function Abnormal, Renal Impairment, Rhabdomyolysis, Drug Interaction
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Ketoconazole
Adverse event in 71 year old male receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-04-05
Patient: 71 year old male, weighing 56.0 kg (123.2 pounds)
Adverse reactions / side effects: Rhabdomyolysis, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zocor (Simvastatin)
Other drugs received by patient: Aspirin; Clopidogrel Bisulfate; Folic Acid; Furosemide; Ramipril
Adverse event in 75 year old male receiving Zocor (Simvastatin)
Reported by a physician from United States on 2007-03-30
Patient: 75 year old male
Adverse reactions / side effects: Rhabdomyolysis, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Januvia
Administration route: Oral
Indication: Diabetes Mellitus Inadequate Control
Start date: 2006-12-04
End date: 2006-12-26
Januvia
Administration route: Oral
Start date: 2006-11-20
End date: 2006-12-01
Zocor
Administration route: Oral
Indication: Hyperlipidaemia
Start date: 2006-08-01
End date: 2006-12-26
Other drugs received by patient: Olmesartan Medoxomil; Olmesartan Medoxomil; Zetia; Bumetanide; Insulin
Adverse event in 78 year old female receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-03-21
Patient: 78 year old female, weighing 70.0 kg (154.0 pounds)
Adverse reactions / side effects: Paraparesis, Fatigue, Blood Creatine Phosphokinase Increased, Rhabdomyolysis, Sensation of Heaviness, Drug Interaction, Gait Disturbance, Asthenia, Myopathy
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Hypercholesterolaemia
Start date: 2005-08-01
End date: 2007-01-30
Fusidic Acid
Administration route: Oral
Indication: Surgery
Start date: 2007-01-01
End date: 2007-01-30
Other drugs received by patient: Bendroflumethiazide; Dihydrocodeine; Ranitidine; Verapamil
Adverse event in 89 year old male receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-02-08
Patient: 89 year old male, weighing 55.0 kg (121.0 pounds)
Adverse reactions / side effects: Myositis, Rhabdomyolysis
Adverse event resulted in: life threatening event, hospitalization, disablity
Suspect drug(s):
Zocor (Simvastatin)
Other drugs received by patient: Aluminum Hydroxide and Simethicone; Atenolol; Clopidogrel Bisulfate; Acetaminophen and Codeine Phosphate; Crotamiton; Diltiazem Hydrochloride; Mineral OIL; Dothiepin Hydrochloride; Nitroglycerin; Ibuprofen; Indoramin; Isosorbide Mononitrate; Lisinopril; Nicorandil; Pantoprazole; Acetaminophen; Senna
Adverse event in female receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-01-24
Patient: female, weighing 150.0 kg (330.0 pounds)
Adverse reactions / side effects: Rhabdomyolysis, Skin Ulcer, Sepsis, Chronic Obstructive Pulmonary Disease, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization, disablity
Suspect drug(s):
Zocor
Administration route: Oral
Erythromycin
Administration route: Oral
Start date: 2006-03-25
Other drugs received by patient: Amitriptyline Hydrochloride; Bumetanide; Dihydrocodeine; Lisinopril; Metformin; Rosiglitazone Maleate; Levothyroxine Sodium
Adverse event in 64 year old receiving Zocor (Simvastatin)
Reported by a health professional (non-physician/pharmacist) from Denmark on 2007-01-22
Patient: 64 year old
Adverse reactions / side effects: Rhabdomyolysis, Drug Interaction
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zocor
Administration route: Oral
Indication: Blood Cholesterol Increased
Start date: 2006-04-24
End date: 2006-11-01
Citalopram Hydrobromide
Administration route: Oral
Indication: Depression
Start date: 2006-04-24
End date: 2006-09-15
Citalopram Hydrobromide
Administration route: Oral
Start date: 2006-09-15
End date: 2006-11-01
Adverse event in male receiving Zocor (Simvastatin)
Reported by a pharmacist from United States on 2007-01-09
Patient: male, weighing 78.9 kg (173.6 pounds)
Adverse reactions / side effects: Rhabdomyolysis, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Zocor
Dosage: 80mg qhs oral
Administration route: Oral
Indication: Hypercholesterolaemia
Gemfibrozil
Dosage: 600mg bid oral
Administration route: Oral
Indication: Hypercholesterolaemia
Start date: 2006-12-01
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