Reported Xanax Side Effects and Adverse Reactions

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This is an index of reports of adverse events (side effects, adverse reactions, etc.) related to Xanax (Alprazolam). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the side effect / adverse reaction. Or scroll down to view a sample of recent reports further on this page.

Our database includes reports primarily from April 2009 to March 2010. The information is not vetted and should not be cosidered as verified clinical evidence.

All cases (587)

     Anxiety (62), Depression (59), Somnolence (57), more >>

Cases resulting in a serious event (567)

     Anxiety (60), Depression (59), Somnolence (56), more >>

Cases resulting in death (110)

     Drug Toxicity (15), Completed Suicide (15), Intentional Drug Misuse (12), more >>

Cases resulting in life threatening events (44)

     Vomiting (12), Suicide Attempt (12), Somnolence (11), more >>

Cases resulting in hospitalization (233)

     Suicide Attempt (41), Depression (37), Confusional State (25), more >>

Cases resulting in disability (36)

     Anxiety (17), Disability (15), Depression (13), more >>

Cases resulting in other serious reactions (308)

     Anxiety (45), Depression (44), Insomnia (38), more >>

Below is a sample of reports where side effects / adverse reactions may be related to Xanax (Alprazolam). For a complete list and/or a specific selection of reports, please use the links in the index above.

Possible Xanax side effects / adverse reactions in male

Reported by a health professional (non-physician/pharmacist) from United States on 2010-03-30

Patient: male

Reactions: Death, Drug Diversion

Adverse event resulted in: death

Suspect drug(s):
Methadose
Dosage: unk

Lortab
Dosage: unk

Oxycontin
Dosage: unk

Xanax
Dosage: unk

Possible Xanax side effects / adverse reactions in male

Reported by a health professional (non-physician/pharmacist) from United States on 2010-03-30

Patient: male, weighing 71.0 kg (156.2 pounds)

Reactions: Accidental Death, Drug Abuse

Adverse event resulted in: death

Suspect drug(s):
Methadose
    Dosage: unk
    Start date: 2009-06-22
    End date: 2009-06-22

Oxycontin
    Dosage: unk
    Start date: 2009-06-22
    End date: 2009-06-22

Xanax
    Dosage: unk
    Start date: 2009-06-21
    End date: 2009-06-21

Possible Xanax side effects / adverse reactions in female

Reported by a consumer/non-health professional from United States on 2010-03-30

Patient: female, weighing 79.0 kg (173.8 pounds)

Reactions: Pneumonia, Coronary Arterial Stent Insertion, Somnolence, Dysarthria, Thinking Abnormal, Renal Failure, Cardiac Failure, Mental Disorder, Hallucination

Adverse event resulted in: hospitalization

Suspect drug(s):
Chantix
    Dosage: 0.5 mg, 1x/day
    Indication: Smoking Cessation Therapy
    Start date: 2009-03-07

Chantix
Dosage: unk
End date: 2009-06-01

Xanax
Indication: Nervousness

Dilaudid
Dosage: unk
Indication: Pain

Percocet
Dosage: unk
Indication: Pain

Other drugs received by patient: Robaxin; Lovastatin; Premarin; Tizanidine HCL

Possible Xanax side effects / adverse reactions in 28 year old male

Reported by a individual with unspecified qualification from United States on 2010-03-29

Patient: 28 year old male

Reactions: Mental Impairment, Condition Aggravated, Multiple Drug Overdose Intentional, Suicide Attempt, Unevaluable Event, Myocardial Infarction, Self-Medication

Adverse event resulted in: hospitalization

Suspect drug(s):
Suboxone
Dosage: 24 mg sublingual
Indication: Drug Dependence

Xanax
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Valium
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Seroquel
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Klonopin
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Skelaxin
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Possible Xanax side effects / adverse reactions in male

Reported by a consumer/non-health professional from United States on 2010-03-29

Patient: male, weighing 69.8 kg (153.7 pounds)

Reactions: Blood Bilirubin Increased, Weight Decreased, General Physical Condition Abnormal, Impaired Work Ability, Glomerular Filtration Rate Increased, Gilbert's Syndrome, DRY Mouth, Blood Cholesterol Increased, Blood Creatinine Increased, Pancreatic Enlargement, Muscle Spasms, Renal Disorder, Drug Effect Decreased, Glomerular Filtration Rate Decreased, Drug Detoxification, Anxiety, Mental Impairment, Activities of Daily Living Impaired, Insomnia, Drug Dependence, Feeling Abnormal

Adverse event resulted in: disablity

Suspect drug(s):
Xanax
Dosage: 4 mg, 1x/day
Indication: Anxiety

Xanax
Indication: Sleep Disorder

Lipitor
Dosage: unk

Lunesta

Possible Xanax side effects / adverse reactions in 71 year old female

Reported by a individual with unspecified qualification from United States on 2010-03-25

Patient: 71 year old female

Reactions: Family Stress, Impaired Work Ability, Ligament Pain, Tendon Pain, Social Problem, Activities of Daily Living Impaired, Fibromyalgia, Insomnia, Disturbance in Attention, Influenza Like Illness

Suspect drug(s):
Soma

Xanax
Dosage: 1 mg

Neurontin

Morphine Sulfate INJ

Oxycodone HCL
Dosage: 3 mg

Roxicodone

Opana

Possible Xanax side effects / adverse reactions in 71 year old female

Reported by a consumer/non-health professional from United States on 2010-03-25

Patient: 71 year old female

Reactions: Pain, Ligament Pain, Myalgia, Tendon Pain, Sleep Disorder, Fibromyalgia, Disturbance in Attention, Influenza Like Illness

Suspect drug(s):
Morphine Sulfate
Dosage: 350 mg, unk
Indication: Drug USE FOR Unknown Indication

Oxycodone Hydrochloride
Dosage: 3 mg, unk
Indication: Drug USE FOR Unknown Indication

Soma
Indication: Drug USE FOR Unknown Indication

Roxicodone
Indication: Drug USE FOR Unknown Indication

Oxymorphone
Indication: Drug USE FOR Unknown Indication

Xanax
Dosage: 1 mg, unk
Indication: Drug USE FOR Unknown Indication

Neurontin
Indication: Drug USE FOR Unknown Indication

Possible Xanax side effects / adverse reactions in female

Reported by a physician from United States on 2010-03-25

Patient: female, weighing 60.3 kg (132.7 pounds)

Reactions: Suicide Attempt

Adverse event resulted in: life threatening event

Suspect drug(s):
Naproxen
    Dosage: tanezumab/placebo, every 8 weeks
    Indication: Back Pain
    Start date: 2009-09-01
    End date: 2009-12-18

Blinded *NO Subject Drug
    Dosage: tanezumab/placebo, every 8 weeks
    Indication: Back Pain
    Start date: 2009-09-01
    End date: 2009-12-18

Blinded *placebo
    Dosage: tanezumab/placebo, every 8 weeks
    Indication: Back Pain
    Start date: 2009-09-01
    End date: 2009-12-18

Blinded PF-04383119
    Dosage: tanezumab/placebo, every 8 weeks
    Indication: Back Pain
    Start date: 2009-09-01
    End date: 2009-12-18

Naproxen
    Dosage: naproxen/placebo, 2x/day
    Administration route: Oral
    Start date: 2009-09-01
    End date: 2009-12-18

Blinded *NO Subject Drug
    Dosage: naproxen/placebo, 2x/day
    Administration route: Oral
    Start date: 2009-09-01
    End date: 2009-12-18

Blinded *placebo
    Dosage: naproxen/placebo, 2x/day
    Administration route: Oral
    Start date: 2009-09-01
    End date: 2009-12-18

Blinded PF-04383119
    Dosage: naproxen/placebo, 2x/day
    Administration route: Oral
    Start date: 2009-09-01
    End date: 2009-12-18

Xanax
    Dosage: unk
    Administration route: Oral
    Indication: Anxiety
    Start date: 2010-01-01
    End date: 2010-01-13

Acetaminophen
    Dosage: 500 mg, as needed
    Administration route: Oral
    Start date: 2009-09-01

Other drugs received by patient: Tenormin; Norlestrin FE; Norlestrin FE; Vitamin E; Vitamin B-12

Possible Xanax side effects / adverse reactions in 27 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2010-03-25

Patient: 27 year old male

Reactions: Jaundice, Hepatitis Acute

Adverse event resulted in: hospitalization

Suspect drug(s):
Xanax
    Dosage: 0.25 unk, 1x/day
    Administration route: Oral
    Indication: Depression
    Start date: 2010-02-13
    End date: 2010-02-22

Deroxat
    Dosage: 20 mg, 1x/day
    Administration route: Oral
    Indication: Depression
    Start date: 2010-02-16
    End date: 2010-02-22

Possible Xanax side effects / adverse reactions in female

Reported by a individual with unspecified qualification from United States on 2010-03-25

Patient: female, weighing 71.2 kg (156.6 pounds)

Reactions: Surgery

Suspect drug(s):
Depakote
Indication: Drug USE FOR Unknown Indication

Chantix
    Indication: Smoking Cessation Therapy
    Start date: 2010-01-31
    End date: 2010-02-09

Chantix

Chantix
End date: 2010-02-09

Xanax
Indication: Drug USE FOR Unknown Indication

Lyrica
Indication: Drug USE FOR Unknown Indication

Methadone
Indication: Drug USE FOR Unknown Indication

Lasix
Indication: Drug USE FOR Unknown Indication

Klor-CON
Indication: Drug USE FOR Unknown Indication

Percocet
Indication: Drug USE FOR Unknown Indication

Paxil
Indication: Drug USE FOR Unknown Indication

Phenobarbital TAB
Indication: Drug USE FOR Unknown Indication

Possible Xanax side effects / adverse reactions in 42 year old male

Reported by a individual with unspecified qualification from United States on 2010-03-24

Patient: 42 year old male, weighing 118.8 kg (261.5 pounds)

Reactions: Product Substitution Issue, Tachyphrenia, Tinnitus, Vomiting, Nausea, Death of Relative, Pyrexia, Suicidal Ideation, Anxiety, Treatment Failure, Feeling Abnormal

Suspect drug(s):
Zoloft
    Dosage: 50 mg once a day po
    Administration route: Oral
    Indication: Obsessive-Compulsive Disorder

Xanax
    Dosage: 05 mg bid po
    Administration route: Oral
    Indication: Anxiety Disorder

Other drugs received by patient: Tcs?s; Klonopin; Lexapro; Ativan; Wellbutrin; Luvox; Gabriel; Prozac; Trazodone; Remeron; Paxil; Deplin; Zoloft; Seroquel

Possible Xanax side effects / adverse reactions in 62 year old male

Reported by a individual with unspecified qualification from France on 2010-03-24

Patient: 62 year old male

Reactions: Ventricular Extrasystoles, Electrocardiogram T Wave Amplitude Decreased, Ejection Fraction Decreased, Congestive Cardiomyopathy, Myocarditis Infectious

Adverse event resulted in: hospitalization

Suspect drug(s):
Fluvoxamine Maleate
    Dosage: 50 milligram(s); oral
    Administration route: Oral
    Indication: Ill-Defined Disorder

Lorazepam
    Dosage: 2 milligram(s), oral
    Administration route: Oral
    Indication: Ill-Defined Disorder

Lithium Carbonate
    Dosage: 1625 milligram(s), oral
    Administration route: Oral
    Indication: Ill-Defined Disorder
    Start date: 1987-06-15

Xanax
    Dosage: 0.25 milligram(s), oral
    Administration route: Oral
    Indication: Ill-Defined Disorder

Possible Xanax side effects / adverse reactions in male

Reported by a health professional (non-physician/pharmacist) from France on 2010-03-24

Patient: male

Reactions: Confusional State, Anaemia

Adverse event resulted in: hospitalization

Suspect drug(s):
Oxycontin
    Dosage: 100 mg, bid
    Administration route: Oral
    Indication: Cancer Pain
    Start date: 2010-01-14
    End date: 2010-01-22

Oxynorm Capsules 20 MG
    Dosage: unk capsl, unk
    Administration route: Oral
    Indication: Cancer Pain
    Start date: 2010-01-14
    End date: 2010-01-20

Neurontin
    Dosage: 300 mg, daily
    Administration route: Oral
    Indication: Pain
    Start date: 2010-01-12
    End date: 2010-01-20

Amitriptyline HCL
    Dosage: 5 mg, daily
    Administration route: Oral
    Indication: Pain
    Start date: 2001-12-12

Xanax
    Dosage: 0.50 mg, daily
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2010-01-14
    End date: 2010-01-18

Atarax
    Dosage: 25 mg, daily
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Temesta / 00273201 /
    Dosage: 1 mg, tid
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Ezetrol; Speciafoldine; Tardyferon / 00023503 /; Largactil / 00011902 /; Lasix

Possible Xanax side effects / adverse reactions in male

Reported by a consumer/non-health professional from France on 2010-03-24

Patient: male

Reactions: Jaundice, Hepatitis Acute, Hepatocellular Injury, Cholestasis

Adverse event resulted in: hospitalization

Suspect drug(s):
Deroxat
    Dosage: 20mg per day
    Administration route: Oral
    Start date: 2010-02-16
    End date: 2010-02-22

Xanax
    Dosage: .25mg per day
    Administration route: Oral
    Start date: 2010-02-13
    End date: 2010-02-22

Possible Xanax side effects / adverse reactions in 34 year old female

Reported by a physician from France on 2010-03-22

Patient: 34 year old female

Reactions: Abortion Induced

Suspect drug(s):
Depakene
    Dosage: daily
    Administration route: Oral
    Indication: Bipolar Disorder

Xanax
Administration route: Oral
Indication: Bipolar Disorder

Seroquel
    Dosage: daily
    Administration route: Oral
    Indication: Bipolar Disorder

Possible Xanax side effects / adverse reactions in male

Reported by a physician from United States on 2010-03-19

Patient: male

Reactions: Agitation, Therapeutic Agent Toxicity, Liver Disorder, Suicidal Ideation, Mania, Hepatotoxicity, Balance Disorder, Injury, Depression, Incorrect Dose Administered, Panic Disorder, Ascites, Tremor, Anxiety, Insomnia, Memory Impairment, Drug Dependence

Adverse event resulted in: hospitalization

Suspect drug(s):
Xanax
Dosage: 1mg
Start date: 2001-01-01

Lithium Carbonate
Dosage: unk

Risperdal
Dosage: unk

Lunesta

Rozerem
Dosage: unk

Seroquel
Dosage: up to 200 mg daily

Possible Xanax side effects / adverse reactions in 43 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2010-03-18

Patient: 43 year old male

Reactions: Cytolytic Hepatitis, Drug Rash With Eosinophilia and Systemic Symptoms, Thrombocytopenia

Adverse event resulted in: hospitalization

Suspect drug(s):
Xanax
    Dosage: 1 df, 2x/day
    Administration route: Oral
    Indication: Anxiety
    Start date: 2009-09-16
    End date: 2009-11-07

Paroxetine
    Dosage: 1.5 df, 1x/day
    Administration route: Oral
    Start date: 2009-09-30
    End date: 2009-11-07

Lysanxia
    Dosage: 10 drops x3/day
    Administration route: Oral
    Start date: 2009-11-17
    End date: 2009-12-02

BI-Profenid
Administration route: Oral
Indication: Back Pain

Possible Xanax side effects / adverse reactions in 53 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2010-03-18

Patient: 53 year old female

Reactions: Mitral Valve Incompetence, Pulmonary Arterial Hypertension, Tricuspid Valve Disease, Aortic Valve Incompetence

Adverse event resulted in: hospitalization

Suspect drug(s):
Xanax
Dosage: unk
Administration route: Oral

Mediator
    Dosage: 2 df daily
    Indication: Type 2 Diabetes Mellitus
    Start date: 2002-01-01
    End date: 2005-03-21

Glucophage
    Dosage: 2 df, 1x/day
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus

Lasilix
Dosage: unk

Diffu K

Irbesartan
Administration route: Oral
Indication: Hypertension

Previscan
Dosage: 20 mg, unk
Administration route: Oral

Acetaminophen W / Propoxyphene HCL
Administration route: Oral

Duphalac
Administration route: Oral

Imovane
Administration route: Oral

Elisor
Administration route: Oral

Deroxat
    Dosage: unk
    Administration route: Oral
    Indication: Depression
    End date: 2004-01-01

Possible Xanax side effects / adverse reactions in

Reported by a physician from United States on 2010-03-18

Patient: , weighing 90.3 kg (198.6 pounds)

Reactions: Suicide Attempt, Suicidal Ideation

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Benicar
    Dosage: per oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Lyrica
    Dosage: 300 mg (100 mg,tid),per oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2009-06-25

Xanax
Indication: Drug USE FOR Unknown Indication

Savella
Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Diovan; Effexor (Venlafaxine Hydrochloride) (Venlafaxine Hydrochloride); Tramadol HCL; Vytorin; Aspirin

Possible Xanax side effects / adverse reactions in female

Reported by a consumer/non-health professional from United Kingdom on 2010-03-18

Patient: female

Reactions: Breast Cancer, Drug Ineffective, Somnolence

Suspect drug(s):
Xanax
Dosage: 1.5 mg, 1x/day
Indication: Anxiety Disorder

Valium
Indication: Anxiety Disorder

Prozac
Indication: Anxiety Disorder

Paroxetine Hydrochloride
Indication: Anxiety Disorder

Moclobemide
Indication: Depression

Possible Xanax side effects / adverse reactions in 45 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2010-03-18

Patient: 45 year old female

Reactions: Death, Intentional Drug Misuse

Adverse event resulted in: death

Suspect drug(s):
Xanax

Oxycontin

Alcohol

Possible Xanax side effects / adverse reactions in male

Reported by a physician from United States on 2010-03-18

Patient: male

Reactions: Death

Adverse event resulted in: death

Suspect drug(s):
Xanax

Methadone Hydrochloride

Lortab

Oxycontin

Possible Xanax side effects / adverse reactions in female

Reported by a consumer/non-health professional from United States on 2010-03-18

Patient: female

Reactions: Weight Decreased, Arthralgia, Diarrhoea, Insomnia, Withdrawal Syndrome, Hyperhidrosis, Paraesthesia

Suspect drug(s):
Xanax
    Dosage: 2 mg at bedtime
    Indication: Insomnia
    End date: 2010-02-04

Neurontin
    Dosage: 2400 mg, unk
    Indication: Neuropathy Peripheral
    End date: 2010-02-04

Lunesta
    Dosage: 3 mg at bedtime
    Administration route: Oral
    Indication: Insomnia
    Start date: 2008-01-01
    End date: 2010-02-04

Lunesta
    Dosage: 3 mg at bedtime
    Administration route: Oral
    Start date: 2010-02-11

Hydrocodone
    Dosage: 40 mg, unk
    Indication: Rheumatoid Arthritis
    End date: 2010-02-04

Hydrocodone
Indication: Pain

Baclofen
    Dosage: unk
    Indication: Muscle Spasms
    End date: 2010-02-04

Possible Xanax side effects / adverse reactions in 35 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2010-03-17

Patient: 35 year old female

Reactions: Electrocardiogram QT Prolonged, Bladder Dilatation, Hypoventilation, Hypercapnia, Somnolence

Adverse event resulted in: hospitalization

Suspect drug(s):
Xanax
    Dosage: unk
    Administration route: Oral
    Start date: 2010-01-01
    End date: 2010-01-01

Effexor
    Dosage: unk
    Start date: 2010-01-01
    End date: 2010-01-01

Zolpidem
    Dosage: unk
    Administration route: Oral
    Start date: 2010-01-01
    End date: 2010-01-01

Lexomil
    Dosage: unk
    Administration route: Oral
    Start date: 2010-01-01
    End date: 2010-01-01

Possible Xanax side effects / adverse reactions in female

Reported by a physician from United States on 2010-03-17