|
Index of reports
> Cases resulting in death (52)
> Cases with Alanine Aminotransferase Increased (10)
Below is the selection of adverse event reports related to Voltaren (Diclofenac) that includes cases resulting in death where reactions include alanine aminotransferase increased.
Adverse event in 20 year old male receiving Voltaren (Diclofenac)
Reported by a health professional (non-physician/pharmacist) from Japan on 2007-07-16
Patient: 20 year old male, weighing 55.0 kg (121.0 pounds)
Adverse reactions / side effects: Blood Bilirubin Increased, Drug Eruption, Disseminated Intravascular Coagulation, Pyrexia, Haematocrit Decreased, RED Blood Cell Count Decreased, Gamma-Glutamyltransferase Increased, Dermatitis Bullous, Blood Creatinine Increased, Melaena, Blister, Stevens-Johnson Syndrome, White Blood Cell Count Increased, Blood Pressure Increased, Pneumonia, Histiocytosis Haematophagic, Blood Urea Increased, Alanine Aminotransferase Increased, Life Support, Pulmonary Haemorrhage, Mucosal Erosion, Haemoglobin Decreased, Aspartate Aminotransferase Increased, Platelet Count Decreased, Skin Erosion
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Voltaren
Dosage: unk, unk
Administration route: Oral
Indication: Pyrexia
Voltaren
Dosage: 25 mg/day
Start date: 2007-03-22
End date: 2007-03-29
Loxoprofen
Dosage: 60 mg/day
Administration route: Oral
Indication: Headache
Start date: 2007-03-28
End date: 2007-04-03
Meropen
Dosage: 1.5 g/day
Indication: Infection
Start date: 2007-03-23
End date: 2007-03-28
Other drugs received by patient: Minocycline HCL; Rocephin; Zyvox; Amikacin; Funguard
Adverse event in 20 year old male receiving Voltaren (Diclofenac)
Reported by a health professional (non-physician/pharmacist) from Japan on 2007-07-16
Patient: 20 year old male, weighing 55.0 kg (121.0 pounds)
Adverse reactions / side effects: Blood Bilirubin Increased, Drug Eruption, Disseminated Intravascular Coagulation, Pyrexia, Haematocrit Decreased, RED Blood Cell Count Decreased, Gamma-Glutamyltransferase Increased, Dermatitis Bullous, Blood Creatinine Increased, Melaena, Blister, Stevens-Johnson Syndrome, White Blood Cell Count Increased, Blood Pressure Increased, Pneumonia, Histiocytosis Haematophagic, Blood Urea Increased, Alanine Aminotransferase Increased, Life Support, Pulmonary Haemorrhage, Mucosal Erosion, Haemoglobin Decreased, Aspartate Aminotransferase Increased, Platelet Count Decreased, Skin Erosion
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Voltaren
Dosage: unk, unk
Administration route: Oral
Indication: Pyrexia
Voltaren
Dosage: 25 mg/day
Start date: 2007-03-22
End date: 2007-03-29
Loxoprofen
Dosage: 60 mg/day
Administration route: Oral
Indication: Headache
Start date: 2007-03-28
End date: 2007-04-03
Meropen
Dosage: 1.5 g/day
Indication: Infection
Start date: 2007-03-23
End date: 2007-03-28
Other drugs received by patient: Minocycline HCL; Rocephin; Zyvox; Amikacin; Funguard
Adverse event in 70 year old female receiving Voltaren (Diclofenac)
Reported by a physician from Japan on 2007-07-13
Patient: 70 year old female, weighing 36.0 kg (79.2 pounds)
Adverse reactions / side effects: Hyperhidrosis, Cardiac Massage, Blood Creatinine Increased, White Blood Cell Count Increased, Metabolic Acidosis, Urine Output Decreased, Blood Lactate Dehydrogenase Increased, Hypotension, Haemodialysis, Respiratory Rate Decreased, Heart Rate Decreased, Aspartate Aminotransferase Increased, Depressed Level of Consciousness, Intubation, Anaphylactic Shock, Pallor, Haematocrit Decreased, RED Blood Cell Count Decreased, Tachypnoea, Oxygen Supplementation, Hepatitis Fulminant, Oxygen Saturation Decreased, Blood Urea Increased, Mydriasis, Alanine Aminotransferase Increased, Drug Hypersensitivity, Life Support, Hepatic Enzyme Increased, Haemoglobin Decreased, Blood Glucose Decreased, Catheterisation Cardiac, Feeling Abnormal, Electrocardiogram ST Segment Elevation
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Voltaren (Diclofenac)
Other drugs received by patient: Loxonin; Pentagin; Aspirin; Ticlopidine HCL; Sigmart; Lansoprazole; Artist; Ferromia
Adverse event in 70 year old female receiving Voltaren (Diclofenac)
Reported by a physician from Japan on 2007-07-13
Patient: 70 year old female, weighing 36.0 kg (79.2 pounds)
Adverse reactions / side effects: Hyperhidrosis, Cardiac Massage, Blood Creatinine Increased, White Blood Cell Count Increased, Metabolic Acidosis, Blood Lactate Dehydrogenase Increased, Hypotension, Urine Output Decreased, Haemodialysis, Respiratory Rate Decreased, Heart Rate Decreased, Aspartate Aminotransferase Increased, Depressed Level of Consciousness, Anaphylactic Shock, Pallor, Haematocrit Decreased, RED Blood Cell Count Decreased, Tachypnoea, Oxygen Supplementation, Hepatitis Fulminant, Oxygen Saturation Decreased, Blood Urea Increased, Mydriasis, Drug Hypersensitivity, Alanine Aminotransferase Increased, Life Support, Hepatic Enzyme Increased, Haemoglobin Decreased, Blood Glucose Decreased, Catheterisation Cardiac, Feeling Abnormal, Electrocardiogram ST Segment Elevation
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Voltaren (Diclofenac)
Other drugs received by patient: Loxonin; Pentagin; Aspirin; Ticlopidine HCL; Sigmart; Lansoprazole; Artist; Ferromia
Adverse event in 2 year old male receiving Voltaren (Diclofenac)
Reported by a individual with unspecified qualification from Japan on 2007-07-02
Patient: 2 year old male, weighing 13.0 kg (28.6 pounds)
Adverse reactions / side effects: Blood Bilirubin Increased, Myoglobinuria, Blood Creatine Phosphokinase Increased, Hepatic Necrosis, Rhabdomyolysis, Hepatic Failure, Resuscitation, Hypoxia, Myoglobin Blood Increased, Blood Creatinine Increased, Blood Urea Increased, Metabolic Acidosis, Alanine Aminotransferase Increased, Haemodialysis, Hepatic Steatosis, Renal Failure, Aspartate Aminotransferase Increased, Depressed Level of Consciousness, Prothrombin Time Shortened, Retroperitoneal Neoplasm, Bradycardia, Obstructive Airways Disorder, Venous Occlusion
Adverse event resulted in: death, life threatening event
Suspect drug(s):
Voltaren
Nitrous Oxide W / Oxygen
Vecuronium Bromide
Fentanyl
Adverse event in 70 year old male receiving Voltaren (Diclofenac)
Reported by a individual with unspecified qualification from Japan on 2007-07-02
Patient: 70 year old male, weighing 60.0 kg (132.0 pounds)
Adverse reactions / side effects: Blood Bilirubin Increased, Productive Cough, Pruritus, Erythema Annulare, Pyrexia, Dermatitis, C-Reactive Protein Increased, White Blood Cell Count Increased, Pleurisy, Blood Lactate Dehydrogenase Increased, LIP Ulceration, Staphylococcal Infection, Cerebral Infarction, Aspartate Aminotransferase Increased, Insomnia, Depressed Level of Consciousness, Platelet Count Decreased, Hemiplegia, Drug Eruption, Oculomucocutaneous Syndrome, Post Procedural Complication, Culture Urine Positive, Liver Disorder, Lung Neoplasm Malignant, Pleural Effusion, White Blood Cell Count Decreased, Intercostal Neuralgia, Alanine Aminotransferase Increased, Haemorrhoids, Muscular Weakness, Rash, LIP Pain, Haematochezia, Agranulocytosis, Sepsis, Sputum Retention, Cardiac Arrest, Shock, Infection
Adverse event resulted in: death
Suspect drug(s):
Voltaren
Dosage: 25 mg/day
Indication: Wound Complication
Start date: 2006-08-24
End date: 2006-08-24
Voltaren
Dosage: 25 mg/day
Start date: 2006-09-04
End date: 2006-09-23
Voltaren
Dosage: 50 mg/day
Start date: 2006-09-17
End date: 2006-09-17
Voltaren
Dosage: 50 mg/day
Start date: 2006-09-20
End date: 2006-09-20
Voltaren
Dosage: 50 mg/day
Start date: 2006-09-21
End date: 2006-09-21
Voltaren
Dosage: 50 mg/day
Start date: 2006-09-22
End date: 2006-09-22
Tegretol
Dosage: 100 mg/day
Administration route: Oral
Indication: Wound Complication
Start date: 2006-09-22
End date: 2006-09-23
Other drugs received by patient: Amoban; Zolpidem; Rohypnol; Ubretid; Spelear; Selbex; Sennoside; Takepron; Naproxen; Aspirin; Polaramine; Aminofluid; Omepral; Cataclot; Solu-Medrol; Soldem 3A; Multivitamin Additive; Heparin Sodium; Pacil; Pansporin; Finibax; Flumarin; Perdipine; Potacol-R; Radicut; NEO-Minophagen C; LOW Molecular Dextran L; Bisolvon; Magmitt Kenei; Cercine; Phenobarbital TAB; Mobic; Loxonin; Distilled Water; Ketoprofen; Laxoberon; Rinderon-VG; Wakobital; Serum Albumin Human; Humulin 70 / 30; Ropivacaine; Aminotripa 1; Aminotripa 2
Adverse event in 82 year old male receiving Voltaren (Diclofenac)
Reported by a individual with unspecified qualification from Italy on 2007-06-25
Patient: 82 year old male
Adverse reactions / side effects: Blood Bilirubin Increased, Jaundice, Hepatic Neoplasm Malignant, Antibody Test Abnormal, Hepatic Failure, Neoplasm, Hepatomegaly, Pulmonary Oedema, Small Intestinal Haemorrhage, Thrombocytopenia, Endoscopy Abnormal, Hepatitis Fulminant, Alanine Aminotransferase Increased, Duodenal Ulcer, Coagulation Time Shortened, Gastric Haemorrhage, Renal Failure, Aspartate Aminotransferase Increased
Adverse event resulted in: death
Suspect drug(s):
Glibomet
Dosage: 400 glibe - 2.5 metf mg/day
Administration route: Oral
Indication: Diabetes Mellitus non-Insulin-Dependent
Start date: 2006-12-03
End date: 2007-05-03
Voltaren
Dosage: 75 mg/day
Indication: Bone Pain
Start date: 2007-04-30
End date: 2007-05-02
Adverse event in 41 year old male receiving Voltaren (Diclofenac)
Reported by a physician from Japan on 2007-05-11
Patient: 41 year old male, weighing 60.0 kg (132.0 pounds)
Adverse reactions / side effects: Brain Death, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Calcium Increased, Pyrexia, C-Reactive Protein Increased, Brain Oedema, Blood Creatinine Increased, White Blood Cell Count Increased, Mydriasis, Brain Stem Haemorrhage, Blood Urea Increased, Dyspnoea, Urine Output Decreased, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Dependence ON Respirator, Haemodialysis, Brain Stem Syndrome, Dehydration, Aspartate Aminotransferase Increased, Platelet Count Decreased, Blood Pressure Decreased
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Voltaren (Diclofenac)
Other drugs received by patient: Adona; Transamin; Primperan INJ; Gaster; Glyceol
Adverse event in 41 year old male receiving Voltaren (Diclofenac)
Reported by a physician from Japan on 2007-04-06
Patient: 41 year old male, weighing 60.0 kg (132.0 pounds)
Adverse reactions / side effects: Brain Death, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Calcium Increased, Pyrexia, C-Reactive Protein Increased, Brain Oedema, Blood Creatinine Increased, White Blood Cell Count Increased, Mydriasis, Brain Stem Haemorrhage, Blood Urea Increased, Dyspnoea, Urine Output Decreased, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Dependence ON Respirator, Haemodialysis, Brain Stem Syndrome, Dehydration, Aspartate Aminotransferase Increased, Platelet Count Decreased, Blood Pressure Decreased
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Voltaren (Diclofenac)
Other drugs received by patient: Adona; Transamin; Primperan INJ; Gaster; Glyceol
Adverse event in 41 year old male receiving Voltaren (Diclofenac)
Reported by a physician from Japan on 2007-03-16
Patient: 41 year old male, weighing 60.0 kg (132.0 pounds)
Adverse reactions / side effects: Brain Death, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Calcium Increased, Pyrexia, C-Reactive Protein Increased, Brain Oedema, Blood Creatinine Increased, White Blood Cell Count Increased, Mydriasis, Brain Stem Haemorrhage, Blood Urea Increased, Dyspnoea, Urine Output Decreased, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Dependence ON Respirator, Haemodialysis, Brain Stem Syndrome, Dehydration, Aspartate Aminotransferase Increased, Platelet Count Decreased, Blood Pressure Decreased
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Voltaren (Diclofenac)
Other drugs received by patient: Adona; Transamin; Primperan INJ; Gaster; Glyceol
|
