Thalomid (Thalidomide) - Adverse Event Reports - Other Serious Reactions - Disease Progression

Adverse event in 35 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-10-29

Patient: 35 year old male

Adverse reactions / side effects: Weight Decreased, Light Chain Disease, Hepatic Failure, Multiple Myeloma, Constipation, Disease Progression, Fatigue, Anorexia, Platelet Count Decreased, Dizziness, Asthenia, Thrombocytopenia

Adverse event resulted in: death

Suspect drug(s):
Thalomid (Thalidomide)

Other drugs received by patient: Decadron; Omeprazole; Oxycontin; Bactrim; Acyclovir; Senokot; Allopurinol; Doxorubicin HCL; Bortezomib (Bortezomib)

Adverse event in 79 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-10-24

Patient: 79 year old male

Adverse reactions / side effects: Blood Urea Increased, Multiple Myeloma, Fall, Loss of Consciousness, Disease Progression, Haemoglobin Decreased, Blood Immunoglobulin G Increased, Haematocrit Decreased, RED Blood Cell Count Decreased, Limb Injury, NO Therapeutic Response, Platelet Count Decreased

Suspect drug(s):
Thalomid (Thalidomide)

Other drugs received by patient: Cozaar; Lipitor; Nexium; Colace (Docusate Sodium); B Complex ELX; Magnesium (Magnesium); Coumadin; Selenium (Selenium); SAW Palmetto (Serenoa Repens)

Adverse event in 78 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-10-16

Patient: 78 year old male

Adverse reactions / side effects: Plasmacytosis, Respiratory Disorder, Pneumonia, Multiple Myeloma, Chronic Obstructive Pulmonary Disease, Disease Progression

Adverse event resulted in: death

Suspect drug(s):
Thalomid (Thalidomide)

Other drugs received by patient: Combivent; Decadron

Adverse event in 35 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-10-10

Patient: 35 year old male

Adverse reactions / side effects: Weight Decreased, Light Chain Disease, Hepatic Failure, Multiple Myeloma, Constipation, Disease Progression, Anorexia, Dizziness, Thrombocytopenia

Adverse event resulted in: death

Suspect drug(s):
Thalomid (Thalidomide)

Other drugs received by patient: Decadron; Omeprazole; Oxycontin; Bactrim; Acyclovir; Senokot (Senna Fruit) (Tablets); Allopurinol; Doxorubicin HCL; Bortezomib (Bortezomib)

Adverse event in 66 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-07-23

Patient: 66 year old male

Adverse reactions / side effects: Fluid Overload, Coronary Artery Disease, Cardiac Failure Congestive, Disease Progression, Nephrotic Syndrome, Renal Failure Acute

Adverse event resulted in: death

Suspect drug(s):
Thalomid
    Dosage: 150 mg, qd, oral, 200 mg, qd, oral
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-11-13
    End date: 2007-03-01

Thalomid
    Dosage: 150 mg, qd, oral, 200 mg, qd, oral
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-10-16

Adverse event in receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-07-03

Patient:

Adverse reactions / side effects: Pulmonary Toxicity, Neuropathy Peripheral, Pleural Effusion, Neutropenia, Disease Progression

Adverse event resulted in: death

Suspect drug(s):
Thalomid
    Dosage: 100mg escalating to 400mg, per day, oral
    Administration route: Oral
    Indication: Myelofibrosis

Gleevec
    Dosage: 600 mg, per day
    Indication: Myelofibrosis

Adverse event in 96 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-06-15

Patient: 96 year old male

Adverse reactions / side effects: Acute Leukaemia, Myelodysplastic Syndrome, Disease Progression

Adverse event resulted in: death

Suspect drug(s):
Thalomid (Thalidomide)

Adverse event in 56 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-06-14

Patient: 56 year old male

Adverse reactions / side effects: Anaemia Haemolytic Autoimmune, Disease Progression

Adverse event resulted in: hospitalization

Suspect drug(s):
Thalomid (Thalidomide)

Other drugs received by patient: Senokot S (Coloxyl with Senna); Compazine; Culturelle (Culturelle); K-DUR 10; Naprosyn (Naproxein); Protonix; Immunoglobulin (Immunoglobulin)

Adverse event in 68 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-06-08

Patient: 68 year old male

Adverse reactions / side effects: Neuropathy, Osteonecrosis, Disease Progression

Suspect drug(s):
Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2003-04-28
    End date: 2005-12-01

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-01-19
    End date: 2007-01-01

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2007-02-21
    End date: 2007-03-01

Adverse event in 68 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-06-07

Patient: 68 year old male

Adverse reactions / side effects: Neuropathy, Osteonecrosis, Disease Progression

Suspect drug(s):
Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2003-04-28
    End date: 2005-12-01

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-01-19
    End date: 2007-01-01

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2007-02-21
    End date: 2007-03-01

Adverse event in 56 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-06-07

Patient: 56 year old male

Adverse reactions / side effects: Multiple Myeloma, Haemolytic Anaemia, Disease Progression

Adverse event resulted in: hospitalization

Suspect drug(s):
Thalomid (Thalidomide)

Other drugs received by patient: Senokot; Compazine; Culturelle (Culturelle); Prednisone TAB; K-DUR 10; Cytoxan; Naprosyn; Protonix

Adverse event in 63 year old female receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-05-22

Patient: 63 year old female

Adverse reactions / side effects: Protein Urine Present, Femur Fracture, Spinal Fracture, Drug Ineffective, Disease Progression

Suspect drug(s):
Thalomid (Thalidomide)

Adverse event in receiving Thalomid (Thalidomide)

Reported by a individual with unspecified qualification from United States on 2007-05-18

Patient:

Adverse reactions / side effects: Pulmonary Toxicity, Neuropathy Peripheral, Neutropenia, Disease Progression

Adverse event resulted in: death

Suspect drug(s):
Thalomid
    Dosage: 100mg escalating to 400mg, per day, oral
    Administration route: Oral
    Indication: Myelofibrosis

Gleevec
    Dosage: 600 mg, per day
    Indication: Myelofibrosis

Adverse event in 71 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-05-09

Patient: 71 year old male

Adverse reactions / side effects: Malaise, Renal Failure, Diabetes Mellitus, Anorexia, Hyperviscosity Syndrome, Multiple Myeloma, Hypercalcaemia, Disease Progression

Adverse event resulted in: death

Suspect drug(s):
Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2003-04-23
    End date: 2004-01-07

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-03-01
    End date: 2007-03-21

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-02-19

Other drugs received by patient: Dexamethasone TAB; Allopurinol; Toprol-XL

Adverse event in 56 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-04-27

Patient: 56 year old male

Adverse reactions / side effects: Aspiration Bone Marrow Abnormal, Plasmacytoma, Vomiting, Nausea, Pancytopenia, Oral Neoplasm, Disease Progression, Paraesthesia, Diarrhoea, Respiratory Failure, Asthenia

Adverse event resulted in: hospitalization

Suspect drug(s):
Thalomid
    Dosage: 1600 mg qhs oral ; oral ; qhs oral
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2002-12-01

Thalomid
    Dosage: 1600 mg qhs oral ; oral ; qhs oral
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2007-01-01

Thalomid
    Dosage: 1600 mg qhs oral ; oral ; qhs oral
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2007-03-01

Dexamethasone TAB
    Dosage: 200 mg day 1 oral ; 20 mg, days 4, 8, and 11, oral
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2002-01-01

Other drugs received by patient: Velcade; Cisplatin; Adriamycin PFS; Cyclophosphamide; Etoposide

Adverse event in female receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-04-09

Patient: female

Adverse reactions / side effects: Renal Failure, Drug Ineffective, Swelling, Tricuspid Valve Incompetence, Multiple Myeloma, Disease Progression

Suspect drug(s):
Thalomid (Thalidomide)

Adverse event in 63 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-04-06

Patient: 63 year old male

Adverse reactions / side effects: Cardio-Respiratory Arrest, Acute Respiratory Failure, Disease Progression

Adverse event resulted in: death

Suspect drug(s):
Thalomid (Thalidomide)

Adverse event in male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-03-28

Patient: male

Adverse reactions / side effects: Metastasis, Neuropathy Peripheral, Disease Progression

Adverse event resulted in: death

Suspect drug(s):
Celebrex

Cytoxan
    Indication: Metastatic Neoplasm

Thalomid
    Administration route: Oral
    Indication: Metastatic Neoplasm
    Start date: 2006-02-03
    End date: 2006-01-01

Etoposide

Adverse event in 65 year old female receiving Thalomid (Thalidomide)

Reported by a health professional (non-physician/pharmacist) from United States on 2007-03-26

Patient: 65 year old female, weighing 41.0 kg (90.2 pounds)

Adverse reactions / side effects: Haemoglobin Decreased, Death, Full Blood Count Abnormal, Pain, Platelet Count Decreased, Blood Creatinine Increased, Asthenia, Disease Progression

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Decadron
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2005-02-09

Thalomid
    Administration route: Oral
    Indication: Gammopathy
    Start date: 2005-02-09
    End date: 2005-03-01

Thalomid
    Administration route: Oral
    Start date: 2005-04-01
    End date: 2006-05-01

Other drugs received by patient: Decadron; Velcade; [therapy Unspecified]

Adverse event in receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-03-22

Patient:

Adverse reactions / side effects: Hypersensitivity, Pulmonary Embolism, Brain Stem Glioma, Constipation, Disease Progression, Drug Toxicity, Neuropathy Peripheral, Astrocytoma, LOW Grade, Liver Function Test Abnormal, Hydrocephalus, Lymphopenia, Rash, Shunt Infection, Haemoglobin Decreased, Abscess, Deep Vein Thrombosis, Leukopenia

Adverse event resulted in: death

Suspect drug(s):
Thalomid
    Dosage: 12mg/kg, incr. 20% wkly. to 24mg/kg or 1000mg, oral
    Administration route: Oral
    Indication: Brain Stem Glioma

Thalomid
    Dosage: 12mg/kg, incr. 20% wkly. to 24mg/kg or 1000mg, oral
    Administration route: Oral
    Indication: Glioblastoma Multiforme

Other drugs received by patient: Dexamethasone TAB; Coumadin

Adverse event in 71 year old female receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-03-16

Patient: 71 year old female, weighing 101.0 kg (222.2 pounds)

Adverse reactions / side effects: Atelectasis, Performance Status Decreased, Pneumonia, Nausea, Constipation, Failure TO Thrive, Somnolence, Disease Progression, Drug Toxicity, Activities of Daily Living Impaired, Dehydration, Oedema Peripheral, Depressed Level of Consciousness, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Suspect drug(s):
Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Uterine Cancer
    Start date: 2007-01-25
    End date: 2007-02-17

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Uterine Cancer
    Start date: 2007-02-22

Adverse event in 89 year old female receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-03-15

Patient: 89 year old female

Adverse reactions / side effects: Thrombosis, Osteoporosis, Spinal Fracture, International Normalised Ratio Increased, Pulmonary Embolism, Thrombocythaemia, Multiple Myeloma, Disease Progression, Cardio-Respiratory Arrest, NO Therapeutic Response, Compression Fracture, Myocardial Infarction

Adverse event resulted in: death

Suspect drug(s):
Thalomid
    Dosage: 50 mg, 1 in 1 d, oral
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-05-17
    End date: 2006-08-01

Thalomid
    Dosage: 50 mg, 1 in 1 d, oral
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2006-08-15
    End date: 2006-09-20

Other drugs received by patient: Lovenox; Allopurinol; Nexium; Furosemide; Hyzaar; Neurontin; Detrol; Dexamethasone TAB; Hydrea; Coumadin

Adverse event in 58 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-03-07

Patient: 58 year old male

Adverse reactions / side effects: Spinal Cord Compression, Soft Tissue Disorder, Confusional State, Dyspnoea, Mass, Mental Status Changes, Multiple Myeloma, Fall, Paraesthesia, Disease Progression, Paraplegia, NO Therapeutic Response, Metastases TO Central Nervous System, Spinal Column Stenosis

Adverse event resulted in: death, hospitalization, disablity

Suspect drug(s):
Thalomid (Thalidomide)

Other drugs received by patient: Dexamethasone TAB; Vincristine; Adriamycin PFS

Adverse event in 60 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-02-27

Patient: 60 year old male

Adverse reactions / side effects: Cardiac Valve Disease, Subacute Endocarditis, Arthritis Bacterial, Disease Progression, Infection

Adverse event resulted in: hospitalization

Suspect drug(s):
Thalomid (Thalidomide)

Adverse event in 41 year old male receiving Thalomid (Thalidomide)

Reported by a physician from United States on 2007-02-16

Patient: 41 year old male

Adverse reactions / side effects: Blood Immunoglobulin A Decreased, Mass, Gastric Disorder, Disease Progression, Weight Increased, Blood Immunoglobulin G Increased, Protein Total Increased, Blood Immunoglobulin M Decreased

Suspect drug(s):
Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2005-03-01
    End date: 2005-05-01

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2005-05-04
    End date: 2005-09-01

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2005-09-27
    End date: 2006-11-03

Thalomid
    Dosage: see image
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2007-01-17