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This is an index of reports of adverse events (side effects, adverse reactions, etc.) related to Sandimmune (Cyclosporine). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the side effect / adverse reaction. Or scroll down to view a sample of recent reports further on this page.
Our database includes reports from Jan 2007 to Dec 2007. The information is not vetted and should not be cosidered as verified clinical evidence.
All cases (158)
Cases resulting in a serious event (157)
Cases resulting in death (54)
Cases resulting in life threatening events (7)
Cases resulting in hospitalization (71)
Cases resulting in disability (13)
Cases resulting in other serious reactions (89)
Below is a sample of reports where side effects / adverse reactions may be related to Sandimmune (Cyclosporine). For a complete list and/or a specific selection of reports, please use the links in the index above.
Adverse event in 48 year old female receiving Sandimmune (Cyclosporine)
Reported by a physician from Japan on 2007-10-31
Patient: 48 year old female
Adverse reactions / side effects: RED Blood Cell Schistocytes Present, Acute Graft Versus Host Disease, RED Blood Cell Abnormality, Pulmonary Alveolar Haemorrhage, Blood Lactate Dehydrogenase Increased, Thrombotic Microangiopathy, Herpes Zoster, Multi-Organ Failure, Reticulocyte Count Increased, Respiratory Failure, Acute Respiratory Distress Syndrome, Haemolytic Anaemia, Thrombocytopenia
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Sandimmune (Cyclosporine)
Adverse event in 46 year old female receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-10-29
Patient: 46 year old female
Adverse reactions / side effects: Cytomegalovirus Antigen Positive, Haptoglobin Decreased, RED Blood Cell Abnormality, Proteinuria, Blood Lactate Dehydrogenase Increased, Thrombotic Microangiopathy, Focal Glomerulosclerosis
Adverse event resulted in: disablity
Suspect drug(s):
Cyclophosphamide
Neoral
Dosage: unk, unk
Administration route: Oral
Indication: Allogenic Bone Marrow Transplantation Therapy
End date: 2007-03-22
Sandimmune
Dosage: 3 mg/kg/day
Indication: Allogenic Bone Marrow Transplantation Therapy
Start date: 2006-12-12
Other drugs received by patient: Methotrexate; Campath; Fludarabine Phosphate
Adverse event in 46 year old female receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-10-29
Patient: 46 year old female
Adverse reactions / side effects: Cytomegalovirus Antigen Positive, Haptoglobin Decreased, RED Blood Cell Abnormality, Proteinuria, Blood Lactate Dehydrogenase Increased, Thrombotic Microangiopathy, Focal Glomerulosclerosis
Adverse event resulted in: disablity
Suspect drug(s):
Cyclophosphamide
Neoral
Dosage: unk, unk
Administration route: Oral
Indication: Allogenic Bone Marrow Transplantation Therapy
End date: 2007-03-22
Sandimmune
Dosage: 3 mg/kg/day
Indication: Allogenic Bone Marrow Transplantation Therapy
Start date: 2006-12-12
Other drugs received by patient: Methotrexate; Campath; Fludarabine Phosphate
Adverse event in 48 year old female receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-10-29
Patient: 48 year old female
Adverse reactions / side effects: Pulmonary Haemorrhage, Respiratory Failure, RED Blood Cell Schistocytes Present, Haemolytic Anaemia, Thrombotic Microangiopathy, Thrombocytopenia, Herpes Zoster
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Sandimmune (Cyclosporine)
Adverse event in 57 year old male receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-10-25
Patient: 57 year old male
Adverse reactions / side effects: Hepatic Function Abnormal, Acute Graft Versus Host Disease, Renal Abscess, Rash, Lung Abscess, Aspergillosis, Sinus Tachycardia, Myocarditis Mycotic, Cardiac Hypertrophy, Blood Pressure Decreased
Adverse event resulted in: death
Suspect drug(s):
Sandimmune (Cyclosporine)
Other drugs received by patient: Endoxan; Methotrexate; Prograf; Thiotepa; Cyclophosphamide; Irradiation; Cellcept; Steroids NOS
Adverse event in 1 year old male receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-10-17
Patient: 1 year old male, weighing 8.5 kg (18.7 pounds)
Adverse reactions / side effects: Stem Cell Transplant, Immunosuppressant Drug Level Decreased, Acute Graft Versus Host Disease, Acute Myeloid Leukaemia Recurrent
Adverse event resulted in: death
Suspect drug(s):
Neoral
Dosage: unk, unk
Administration route: Oral
Indication: Bone Marrow Transplant
End date: 2003-08-14
Sandimmune
Dosage: 1.5 mg/kg
Indication: Bone Marrow Transplant
Other drugs received by patient: Methotrexate; Endoxan
Adverse event in 43 year old male receiving Sandimmune (Cyclosporine)
Reported by a physician from Germany on 2007-10-15
Patient: 43 year old male, weighing 84.0 kg (184.8 pounds)
Adverse reactions / side effects: Mean Cell Haemoglobin Concentration Decreased, Blood Triglycerides Increased, Blood Cholesterol Increased, Condition Aggravated, Mean Cell Volume Increased, Blood Creatinine Increased, Hypertriglyceridaemia
Suspect drug(s):
Sandimmune (Cyclosporine)
Other drugs received by patient: Fumaderm
Adverse event in 7 year old female receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Greece on 2007-10-15
Patient: 7 year old female
Adverse reactions / side effects: White Blood Cell Count Decreased, Parvovirus Infection, Blood Urea Increased, Histiocytosis Haematophagic, Parvovirus B19 Serology Positive, Prothrombin Time Prolonged, Haemoglobin Decreased, Activated Partial Thromboplastin Time Prolonged, Haematocrit Decreased, Fibrin D Dimer Increased, Immunosuppression
Adverse event resulted in: death
Suspect drug(s):
Azathioprine
Corticosteroids
Cyclophosphamide
Enbrel
Kineret
Indication: Vasculitis
Start date: 2007-04-14
Methotrexate
Methylprednisolone
Prezolon
Sandimmune
Indication: Vasculitis
Adverse event in 7 year old female receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Greece on 2007-10-15
Patient: 7 year old female
Adverse reactions / side effects: White Blood Cell Count Decreased, Parvovirus Infection, Blood Urea Increased, Histiocytosis Haematophagic, Parvovirus B19 Serology Positive, Prothrombin Time Prolonged, Haemoglobin Decreased, Activated Partial Thromboplastin Time Prolonged, Haematocrit Decreased, Fibrin D Dimer Increased, Immunosuppression
Adverse event resulted in: death
Suspect drug(s):
Azathioprine
Corticosteroids
Cyclophosphamide
Enbrel
Kineret
Indication: Vasculitis
Start date: 2007-04-14
Methotrexate
Methylprednisolone
Prezolon
Sandimmune
Indication: Vasculitis
Adverse event in 66 year old female receiving Sandimmune (Cyclosporine)
Reported by a physician from Japan on 2007-10-11
Patient: 66 year old female, weighing 35.0 kg (77.0 pounds)
Adverse reactions / side effects: Haemolytic Anaemia
Adverse event resulted in: hospitalization
Suspect drug(s):
Cellcept
Dosage: 1000 mg/daily
Administration route: Oral
Indication: Renal Transplant
Start date: 2007-02-01
Sandimmune
Dosage: 60 mg/daily
Indication: Renal Transplant
Start date: 2007-01-31
Simulect
Dosage: 20 mg, day 0
Indication: Renal Transplant
Start date: 2007-01-31
End date: 2007-01-31
Simulect
Dosage: 20 mg, day 4
Start date: 2007-02-04
End date: 2007-02-04
Solu-Medrol
Dosage: 500 mg/daily
Indication: Renal Transplant
Start date: 2007-01-31
Other drugs received by patient: Amlodipine
Adverse event in 60 year old male receiving Sandimmune (Cyclosporine)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-08
Patient: 60 year old male
Adverse reactions / side effects: Hyperkalaemia, Skin Lesion, Kaposi's Sarcoma, Azotaemia, Lymphoedema
Adverse event resulted in: death
Suspect drug(s):
Ciclosporin
Dosage: unk, unk
Administration route: Oral
Indication: Renal Transplant
Start date: 1991-05-18
Neoral
Indication: Renal Transplant
Sandimmune
Dosage: 250 mg, qd
Indication: Renal Transplant
Other drugs received by patient: Azathioprine; Prednisolone; Amlodipine Besylate; CO-Codamol; Gaviscon Liquid ^boehringer Ingelheim^; Isoniazid; Lactulose; Omeprazole; Pyridoxine Hydrochloride
Adverse event in 12 year old male receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-10-08
Patient: 12 year old male
Adverse reactions / side effects: Stomatitis, Acute Graft Versus Host Disease in Skin, Rash, Drug Level Decreased
Suspect drug(s):
Methotrexate
Sandimmune
Dosage: 200 mg/day
Indication: Stem Cell Transplant
Start date: 2006-05-01
End date: 2006-07-01
Other drugs received by patient: Fludarabine Phosphate; Melphalan
Adverse event in male receiving Sandimmune (Cyclosporine)
Reported by a consumer/non-health professional from Italy on 2007-10-05
Patient: male
Adverse reactions / side effects: Dermatitis, Pyrexia, Lipase Increased
Suspect drug(s):
Sandimmune (Cyclosporine)
Adverse event in receiving Sandimmune (Cyclosporine)
Reported by a consumer/non-health professional from Sweden on 2007-10-04
Patient:
Adverse reactions / side effects: Intentional Overdose, Suicide Attempt
Suspect drug(s):
Sandimmune (Cyclosporine)
Adverse event in 4 year old female receiving Sandimmune (Cyclosporine)
Reported by a physician from Germany on 2007-10-02
Patient: 4 year old female
Adverse reactions / side effects: Drug Toxicity, Renal Failure, Acute Hepatic Failure, Drug Interaction, Hepatic Failure, Accidental Overdose
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Sandimmune
Indication: Colitis
Start date: 2007-08-01
Voriconazole
Adverse event in 4 year old female receiving Sandimmune (Cyclosporine)
Reported by a physician from Germany on 2007-10-02
Patient: 4 year old female
Adverse reactions / side effects: Drug Toxicity, Renal Failure, Acute Hepatic Failure, Drug Interaction, Hepatic Failure, Accidental Overdose
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Sandimmune
Indication: Colitis
Start date: 2007-08-01
Voriconazole
Adverse event in 1 year old male receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-10-02
Patient: 1 year old male, weighing 8.5 kg (18.7 pounds)
Adverse reactions / side effects: Stem Cell Transplant, Immunosuppressant Drug Level Decreased, Acute Graft Versus Host Disease, Acute Myeloid Leukaemia Recurrent
Adverse event resulted in: death
Suspect drug(s):
Cyclosporine
Administration route: Oral
Indication: Bone Marrow Transplant
Sandimmune
Dosage: 1.5 mg/kg
Indication: Bone Marrow Transplant
Other drugs received by patient: Methotrexate
Adverse event in male receiving Sandimmune (Cyclosporine)
Reported by a pharmacist from Germany on 2007-10-02
Patient: male
Adverse reactions / side effects: White Blood Cell Count Decreased, Cachexia, Immunosuppressant Drug Level Decreased, Renal Impairment, RED Blood Cell Count Decreased, Dialysis, Blood Albumin Decreased
Adverse event resulted in: hospitalization
Suspect drug(s):
Sandimmune (Cyclosporine)
Other drugs received by patient: Drug Therapy NOS
Adverse event in 54 year old male receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-07-27
Patient: 54 year old male
Adverse reactions / side effects: Multi-Organ Failure, Hepatitis C, Hepatitis C RNA Positive, RED Blood Cell Schistocytes Present, Blood Lactate Dehydrogenase Increased, Thrombotic Microangiopathy
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Sandimmune (Cyclosporine)
Other drugs received by patient: Fresh Frozen Plasma
Adverse event in 54 year old male receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-07-27
Patient: 54 year old male
Adverse reactions / side effects: Multi-Organ Failure, Hepatitis C, Hepatitis C RNA Positive, RED Blood Cell Schistocytes Present, Blood Lactate Dehydrogenase Increased, Thrombotic Microangiopathy
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Sandimmune (Cyclosporine)
Other drugs received by patient: Fresh Frozen Plasma
Adverse event in 85 year old female receiving Sandimmune (Cyclosporine)
Reported by a physician from Switzerland on 2007-07-26
Patient: 85 year old female
Adverse reactions / side effects: Agitation, Confusional State, Personality Change, Drug Interaction, Disorientation, Pyrexia, Serotonin Syndrome, Fall, Muscle Rigidity, C-Reactive Protein Increased, Clonus, Urinary Tract Infection, Hyperreflexia, General Physical Health Deterioration, Akinesia, Antidepressant Drug Level Increased, Anxiety, Heart Rate Increased, Extrapyramidal Disorder
Adverse event resulted in: hospitalization
Suspect drug(s):
Cefuroxime Axetil
Start date: 2007-03-09
End date: 2007-03-19
Cipralex
Dosage: 10 mg/d
Indication: Depression
Start date: 2006-10-01
End date: 2007-03-26
Cipralex
Dosage: 15 mg
Start date: 2007-04-05
End date: 2007-04-06
Sandimmune
Dosage: 125 mg/d
Indication: Renal Transplant
Start date: 1995-01-01
Other drugs received by patient: Imurek; Perfalgan; Vancomycin HCL; Rocephin; Memantine HCL; Haldol; Lorazepam; Rocaltrol; Calcium Chloride; Seroquel
Adverse event in 55 year old female receiving Sandimmune (Cyclosporine)
Reported by a health professional (non-physician/pharmacist) from Croatia (Local Name: Hrvatska) on 2007-07-26
Patient: 55 year old female
Adverse reactions / side effects: Neurotoxicity, Grand MAL Convulsion, Confusional State, Blood Amylase Increased, Insomnia, Dizziness, Memory Impairment, Nervousness
Adverse event resulted in: hospitalization
Suspect drug(s):
Cellcept
Decortin
Lamivudine
Indication: Drug USE FOR Unknown Indication
Lamivudine
Dosage: 150mg given intermittently during the last six months before hospitalisation
Sandimmune
Dosage: 2.5mg/kg/day
Sandimmune
Dosage: slightly tapered
Other drugs received by patient: Nifedipine; Atenolol
Adverse event in female receiving Sandimmune (Cyclosporine)
Reported by a physician from Spain on 2007-07-24
Patient: female
Adverse reactions / side effects: Anaphylactic Reaction, Rash, Erythema, Hypertension
Suspect drug(s):
Sandimmune (Cyclosporine)
Adverse event in 57 year old female receiving Sandimmune (Cyclosporine)
Reported by a physician from Croatia (Local Name: Hrvatska) on 2007-07-19
Patient: 57 year old female, weighing 75.5 kg (166.1 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Rhabdomyolysis, Diabetes Mellitus, Cytomegalovirus Infection, Muscular Weakness
Adverse event resulted in: hospitalization, disablity
Suspect drug(s):
Lescol XL
Dosage: 80 mg, qd
Administration route: Oral
End date: 2007-04-12
Sandimmune
Dosage: 150 mg, qd
Administration route: Oral
Indication: Renal Transplant
Start date: 2007-02-17
Other drugs received by patient: Cellcept; Decortin; Nitrofurantoin; Lacidipine; Furosemide; Controloc; Cortef
Adverse event in 11 year old male receiving Sandimmune (Cyclosporine)
Reported by a individual with unspecified qualification from Japan on 2007-07-18
Patient: 11 year old male, weighing 27.0 kg (59.4 pounds)
Adverse reactions / side effects: Neutrophilia, Leukocytosis
Suspect drug(s):
Neoral
Indication: Renal Transplant
Neoral
Dosage: 350 mg/d
Administration route: Oral
Start date: 2000-08-22
Sandimmune
Dosage: unk, unk
Indication: Renal Transplant
End date: 2000-08-21
Other drugs received by patient: Solu-Medrol; Mizoribine; Valproate Sodium; Amlodipine; Kalimate; Medrol
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