Phytonadione (Phytonadione) - Adverse Event Reports - Serious Event

Toxic Epidermal Necrolysis (3),  Agitation (1),  Haemorrhage (1),  Infusion Related Reaction (1),  Anaphylactic Reaction (1),  Cyanosis (1),  Chest Pain (1),  Hypoxia (1),  Device Malfunction (1)

Adverse event in 56 year old male receiving Phytonadione

Reported by a health professional (non-physician/pharmacist) from United States on 2007-05-09

Patient: 56 year old male

Adverse reactions / side effects: Chest Pain, Infusion Related Reaction

Adverse event resulted in: life threatening event

Suspect drug(s):
Phytonadione

Adverse event in 41 year old male receiving Phytonadione

Reported by a pharmacist from United States on 2007-03-12

Patient: 41 year old male

Adverse reactions / side effects: Agitation, Cyanosis, Anaphylactic Reaction, Hypoxia

Adverse event resulted in: life threatening event

Suspect drug(s):
Phytonadione

Adverse event in 41 year old female receiving Phytonadione

Reported by a health professional (non-physician/pharmacist) from United States on 2007-03-09

Patient: 41 year old female

Adverse reactions / side effects: Haemorrhage, Device Malfunction

Suspect drug(s):
Phytonadione

Adverse event in 54 year old male receiving Phytonadione

Reported by a individual with unspecified qualification from United Kingdom on 2007-01-30

Patient: 54 year old male

Adverse reactions / side effects: Toxic Epidermal Necrolysis

Suspect drug(s):
Propofol
    Dosage: intravenous

Acetaminophen

Omeprazole
    Dosage: 40 mg, intravenous

Actrapid (Insulin Human)
    Dosage: intravenous

Alfentanil

Amoxicillin
    Dosage: 3 gm (1 gm, tid), intravenous

Aquasept (Triclosan)

Bactroban

Calcium Chloride (Calcium Chloride Hexahydrate)

Ceftriaxone
    Dosage: 2 gm, intravenous

Calcium Gluconate
    Dosage: 10 m1, intravenous

Enoxaparin Sodium
    Dosage: 20 mg (20 mg, qd), subcutaneous

Dobutamine (Dobutamine)

Fluconazole
    Dosage: 200 mg, (200 mg, qd), intravenous

Fragmin
    Dosage: 250 iu (250 iu, od)

Furosemide
    Dosage: 40 mg (20 mg, bid), intravenous

Hydrocortisone
    Dosage: 100 mg total

Lactulose
    Dosage: 10 mi

Lansoprazole
    Dosage: 30 mg

Lorazepam
    Dosage: 30 mg

Magnesium Sulphate (Magnseium Sulfate)

Noradrenaline (Noradrenaline)

Chlorpheniramine Maleate
    Dosage: 40 mg (10 mg, qid), intravenous

Potassium Chloride

Potassium Phosphates

Salbutamol (Salbutamol)
    Dosage: (prn)

Potassium Chloride
    Dosage: total 6df daily (tid)

Silver Sulphadiazine (Sulfadiazine Silver)
    Dosage: topical
    Administration route: Topical

Simvastatin
    Dosage: 40 mg (40 mg, qd)

Sodium Bicarbonate IN Plastic Container
    Dosage: 100 mg/hr, intravenous

Sodium Chloride 0.9%
    Dosage: 0.9 %, intravenous

Thiamin (Thiamin Hydrochloride)
    Dosage: 100 mg (qd), oral
    Administration route: Oral

Phytonadione

Tinzaparin (Heparin-Fraction, Sodium Salt)

Other drugs received by patient: Amoxicillin; Aspirin; Atorvent (Ipratropium Bromide); Ciprofloxacin; CO-Amoxiclav (Clavulin); Erythromycin; Metoclopramide; Midodrine Hydrochloride; Pantoprazole Sodium; Tazocin (Pip / Tazo); Vancomycin; Zopiclone (Zopiclone)

Adverse event in 54 year old male receiving Phytonadione

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-01-19

Patient: 54 year old male

Adverse reactions / side effects: Toxic Epidermal Necrolysis

Suspect drug(s):
Albuterol Sulfate
    Dosage: resp
    Indication: Pneumonia

Actrapid (Insulin Human)
    Dosage: iv

Silver Sulphadiazine
    Dosage: top
    Administration route: Topical

Lacgtulose (Lactulose)
    Dosage: 10 ml;

Lansoprazole
    Dosage: 30 mg;

Calcium Gluconate
    Dosage: 10 ml;

Ceftriaxone
    Dosage: 2 gm; iv

Omeprazole
    Dosage: 40 mg; iv

Sodium Chloride (Sodium Chloride) (0.9 Pct)
    Dosage: iv

Fragmin
    Dosage: 2500 iu;

Hydrocortisone
    Dosage: 100 mg; once;

Sando-K
    Dosage: 2 df; tid;

Simvastatin
    Dosage: 40 mg; qd;

Tinzaparin (Tinzaparin)
    Dosage: 3500 mcl;

Alfentanil

Aquasept (Triclosan)

Bactroban

Calcium Chloride (Calcium Chloride Anhydrous)

Dobutamine (Dobutamine)

Lorazepam

Magnesium Sulfate

Norepinephrine Bitartrate

Acetaminophen

Potassium Chloride

Potassium Phosphates

Propofol

Phytonadione

Amoxicillin
    Dosage: 1 gm; tid; iv

Enoxaparin Sodium
    Dosage: 20 mg; qd; sc

Fluconazole
    Dosage: 200 mg; iv

Furosemide
    Dosage: see image

Chlorpheniramine Maleate
    Dosage: 10 mg; qid; iv

Sodium Bicarbonate IN Plastic Container
    Dosage: 100 mg; iv

Thiamine Hydrochloride
    Dosage: 100 mg; qd; po
    Administration route: Oral

Other drugs received by patient: Aspirin; Atrovent; Ciprofloxacin / 00697202 /; Erythromycin; Metoclopramide; Midodrine; Pantoprazole Sodium; Tazocin; Vancomycin; Zopiclone; Amoxicillin; Amoxicillin + Clavulanate Potassium; CO-Codamol

Adverse event in 54 year old male receiving Phytonadione

Reported by a consumer/non-health professional from United Kingdom on 2007-01-18

Patient: 54 year old male

Adverse reactions / side effects: Toxic Epidermal Necrolysis

Suspect drug(s):
Propofol
    Dosage: not reported

Actrapid (Insulin Human)
    Dosage: intravenous

Alfentanil
    Dosage: not reported

Amoxicillin
    Dosage: 1 gm, 3 in 1 d, intravenous

Aquasept (Triclosan)
    Dosage: not reported

Bactroban
    Dosage: not reported

Calcium Chloride
    Dosage: not reported

Calcium Gluconate
    Dosage: 10 ml, not reported

Ceftriaxone
    Dosage: 2 gm, intravenous

Enoxaparin Sodium
    Dosage: 20 mg, 1 in 1 d, subcutaneous

Dobutamine HCL
    Dosage: not reported

Fluconazole
    Dosage: 200 mg, 1 in 1 d, intravenous

Fragmin
    Dosage: 2500 iu, 1 in 1 d, not reported

Furosemide
    Dosage: 20 mg, 2 in 1 d, intravenous

Hydrocortisone
    Dosage: 100 mg, 1 in 1 d, not reported

Lactulose
    Dosage: 10 ml, not reported

Lansoprazole
    Dosage: 30 mg

Lorazepam
    Dosage: not reported

Magnesium Sulfate
    Dosage: not reported

Norepinephrine Bitartrate
    Dosage: not reported

Omeprazole
    Dosage: 40 mg, intravenous

Acetaminophen
    Dosage: not reported

Piriton (Chlorphenamine Maleate)
    Dosage: 10 mg, 4 in 1 d, intravenous

Potassium Chloride
    Dosage: not reported

Potassium Phosphates
    Dosage: not reported

Salbutamol (Salbutamol)
    Dosage: not reported, as necessary

Sando-K
    Dosage: 2 ^df^, 3 in 1 day, not reported
    Indication: Drug USE FOR Unknown Indication

Silver Sulfadiazine
    Dosage: not reported
    Indication: Drug USE FOR Unknown Indication

Simvastatin
    Dosage: 40 mg, 1 in 1d
    Indication: Drug USE FOR Unknown Indication

Sodium Bicarbonate IN Plastic Container
    Dosage: 100 mg, 1 in 1 hr, intravenous
    Indication: Drug USE FOR Unknown Indication

Sodium Chloride 0.9% (Sodium Chloride)
    Dosage: intravenous
    Indication: Drug USE FOR Unknown Indication

Thiamin Chloride TAB
    Dosage: 100 mg, 1 in 1d, oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Tinzaparin (Heparin-Fraction, Sodium Salt)
    Dosage: 3500 iu, not reported
    Indication: Drug USE FOR Unknown Indication

Phytonadione
    Dosage: not reported
    Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Aspirin; Atrovent; Ciporfloxacin (Ciprofloxacin); CO-Amoxiclav (Clavulin); Amoxicillin; Erythromycin; Metoclopramide; Midodrine Hydrochloride; Pantoprazole Sodium; Tazocin (Pip / Tazo); Vancomycin; Zopiclone (Zopiclone)