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Index of reports
> Cases resulting in other serious reactions (144)
> Cases with Drug Interaction (11)
Below is the selection of adverse event reports related to Nexium (Esomeprazole) that includes cases resulting in other serious reactions where reactions include drug interaction.
Adverse event in male receiving Nexium (Esomeprazole)
Reported by a consumer/non-health professional from United States on 2007-10-26
Patient: male, weighing 95.3 kg (209.7 pounds)
Adverse reactions / side effects: Vomiting, Blood Iron Abnormal, Nausea, Adverse Drug Reaction, Drug Interaction, Serum Ferritin Increased, Laboratory Test Abnormal, Diarrhoea, Asthenia, Influenza Like Illness
Suspect drug(s):
Nexium (Esomeprazole)
Other drugs received by patient possibly interacting with the suspect drug:
Lipitor
Administration route: Oral
Indication: Arteriosclerosis
Lipitor
Indication: Blood Cholesterol
Other drugs received by patient: Ecotrin; Aciphex; Atenolol
Adverse event in 71 year old female receiving Nexium (Esomeprazole)
Reported by a physician from Canada on 2007-10-18
Patient: 71 year old female
Adverse reactions / side effects: Haemoglobin Decreased, Drug Interaction, Anaemia Macrocytic
Suspect drug(s):
Nexium (Esomeprazole)
Other drugs received by patient possibly interacting with the suspect drug:
Methotrexate
Indication: Rheumatoid Arthritis
Start date: 1999-01-01
Methotrexate
Dosage: increased
Start date: 2007-02-01
End date: 2007-07-16
Methotrexate
Dosage: decreased
Start date: 2007-08-01
Other drugs received by patient: Plaquenil; Prednisone; Pantoprazole Sodium; Metoprolol; Diltiazem HCL; Aspirin; Nitroglycerin; Risedronate Sodium; Calcium; Vitamin D
Adverse event in 71 year old female receiving Nexium (Esomeprazole)
Reported by a physician from Canada on 2007-10-16
Patient: 71 year old female
Adverse reactions / side effects: Haemoglobin Decreased, Drug Interaction, Anaemia Macrocytic
Suspect drug(s):
Nexium (Esomeprazole)
Other drugs received by patient possibly interacting with the suspect drug:
Methotrexate
Indication: Rheumatoid Arthritis
Start date: 1999-01-01
Methotrexate
Dosage: increased
Start date: 2007-02-01
End date: 2007-07-16
Methotrexate
Start date: 2007-02-01
Other drugs received by patient: Plaquenil; Prednisone; Pantoprazole Sodium; Metoprolol; Diltiazem Hydrochloride; Aspirin; Nitroglycerin; Risedronate Sodium; Calcium; Vitamin D
Adverse event in 48 year old male receiving Nexium (Esomeprazole)
Reported by a individual with unspecified qualification from Germany on 2007-06-21
Patient: 48 year old male, weighing 81.0 kg (178.2 pounds)
Adverse reactions / side effects: Crush Syndrome, Rhabdomyolysis, Drug Interaction, Hypokinesia, Renal Failure, Respiratory Failure, Dialysis, Acute Hepatic Failure
Adverse event resulted in: death, life threatening event
Suspect drug(s):
Simvastatin
Dosage: 40 mg, oral
Administration route: Oral
Indication: LOW Density Lipoprotein Increased
Start date: 2007-01-01
End date: 2007-04-01
Allopurinol
Dosage: 300 mg, oral
Administration route: Oral
Indication: Hypernatraemia
Start date: 2007-01-01
End date: 2007-04-01
Nexium
Dosage: 20 mg, oral
Administration route: Oral
Indication: Gastritis
Start date: 2006-12-01
End date: 2007-01-01
Adverse event in female receiving Nexium (Esomeprazole)
Reported by a consumer/non-health professional from Brazil on 2007-03-21
Patient: female
Adverse reactions / side effects: Weight Decreased, Nausea, Dizziness, Drug Interaction, Depression, Somnolence, Decreased Appetite, Abdominal Pain Upper
Adverse event resulted in: hospitalization
Suspect drug(s):
Nexium (Esomeprazole)
Other drugs received by patient possibly interacting with the suspect drug:
Valium
Administration route: Oral
Indication: Anxiety
Start date: 2005-01-01
Bupropion HCL
Indication: Depression
Start date: 2007-02-13
Adverse event in female receiving Nexium (Esomeprazole)
Reported by a consumer/non-health professional from Brazil on 2007-02-22
Patient: female
Adverse reactions / side effects: Weight Decreased, Nausea, Dizziness, Drug Interaction, Depression, Somnolence, Decreased Appetite, Abdominal Pain Upper
Adverse event resulted in: hospitalization
Suspect drug(s):
Nexium (Esomeprazole)
Other drugs received by patient possibly interacting with the suspect drug:
Valium
Administration route: Oral
Indication: Anxiety
Start date: 2005-01-01
Zetron
Indication: Depression
Start date: 2007-02-13
Adverse event in 70 year old male receiving Nexium (Esomeprazole)
Reported by a physician from France on 2007-02-07
Patient: 70 year old male, weighing 70.0 kg (154.0 pounds)
Adverse reactions / side effects: Drug Interaction, Renal Failure Acute
Suspect drug(s):
Nexium (Esomeprazole)
Other drugs received by patient possibly interacting with the suspect drug:
Nexium
Administration route: Oral
Start date: 2007-01-01
Zovirax
Indication: Encephalitis
Start date: 2006-12-01
Other drugs received by patient: Tahor; Tahor; Nicardipine HCL; Nicardipine HCL
Adverse event in 47 year old male receiving Nexium (Esomeprazole)
Reported by a pharmacist from United States on 2007-02-01
Patient: 47 year old male, weighing 144.0 kg (316.8 pounds)
Adverse reactions / side effects: Drug Ineffective, Drug Interaction, Convulsion
Suspect drug(s):
Fosamax
Administration route: Oral
Lamictal
Administration route: Oral
Indication: Convulsion
Lovenox
Folic Acid
Synthroid
Pentoxifylline
Lexapro
Nexium
Gabapentin
Furosemide
Trazodone Hydrochloride
Lonazolac Calcium
Aspirin
Vitamin D (Unspecified)
Calcium (Unspecified)
Adverse event in male receiving Nexium (Esomeprazole)
Reported by a individual with unspecified qualification from United States on 2007-01-23
Patient: male, weighing 143.8 kg (316.3 pounds)
Adverse reactions / side effects: Drug Ineffective, Drug Interaction, Convulsion
Suspect drug(s):
Lovenox
Dosage: dose: unk
Lamictal
Administration route: Oral
Indication: Convulsion
Folic Acid
Dosage: dose: unk
Levothyroxine Sodium
Dosage: dose: unk
Oxpentifylline
Dosage: dose: unk
Aldendronate Sodium
Dosage: dose: unk
Lexapro
Dosage: dose: unk
Nexium
Dosage: dose: unk
Gabapentin
Dosage: dose: unk
Furosemide
Dosage: dose: unk
Trazodone HCL
Dosage: dose: unk
Calcium Salts
Dosage: dose: unk
Aspirin
Dosage: dose: unk
VIT D
Dosage: dose: unk
Adverse event in 47 year old male receiving Nexium (Esomeprazole)
Reported by a pharmacist from United States on 2007-01-17
Patient: 47 year old male, weighing 144.1 kg (317.0 pounds)
Adverse reactions / side effects: Drug Ineffective, Drug Interaction, Anticonvulsant Drug Level Below Therapeutic, Convulsion
Suspect drug(s):
Nexium
Administration route: Oral
Lamictal
Administration route: Oral
Lovenox
Folic Acid
Synthroid
Pentoxifylline
Fosamax
Lexapro
Gabapentin
Furosemide
Trazodone HCL
Aspirin
Calcium
Vitamin D
Adverse event in 47 year old male receiving Nexium (Esomeprazole)
Reported by a pharmacist from United States on 2007-01-16
Patient: 47 year old male, weighing 143.8 kg (316.3 pounds)
Adverse reactions / side effects: Disease Recurrence, Drug Interaction, Anticonvulsant Drug Level Below Therapeutic, Convulsion
Suspect drug(s):
Lexapro
Dosage: 40 mg qd po
Administration route: Oral
Lamictal
Dosage: 100 mg bid
Indication: Convulsion
Lovenox
Synthroid
Pentoxifylline
Fosamax
Nexium
Gabapentin
Furosemide
Trazodone HCL
Aspirin
Calcium
Folic Acid
Vitamin D
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