Naproxen - Reports of Side Effects and Adverse Reactions

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This is an index of reports of adverse events (side effects, adverse reactions, etc.) related to Naproxen. Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the side effect / adverse reaction. Or scroll down to view a sample of recent reports further on this page.

Our database includes reports from Jan 2007 to Dec 2007. The information is not vetted and should not be cosidered as verified clinical evidence.

All cases (164)

     Gastrointestinal Haemorrhage (15), Completed Suicide (14), Hypotension (10), more >>

Cases resulting in a serious event (161)

     Gastrointestinal Haemorrhage (15), Completed Suicide (14), Hypotension (10), more >>

Cases resulting in death (40)

     Completed Suicide (14), Hypotension (7), Sepsis (6), more >>

Cases resulting in life threatening events (18)

     Hepatic Necrosis (6), Encephalitis (6), Sepsis (3), more >>

Cases resulting in hospitalization (95)

     Gastrointestinal Haemorrhage (12), Haemoglobin Decreased (8), Renal Failure (7), more >>

Cases resulting in disability (4)

     Hypersensitivity (2), Wheezing (2), Increased Bronchial Secretion (2), more >>

Cases resulting in other serious reactions (49)

     Anaphylactic Reaction (4), Hypotension (4), Tachycardia (4), more >>

Below is a sample of reports where side effects / adverse reactions may be related to Naproxen. For a complete list and/or a specific selection of reports, please use the links in the index above.

Adverse event in female receiving Naproxen

Reported by a physician from United States on 2007-10-30

Patient: female, weighing 94.2 kg (207.2 pounds)

Adverse reactions / side effects: non-Cardiac Chest Pain

Adverse event resulted in: hospitalization

Suspect drug(s):
Placebo
    Dosage: twice daily
    Administration route: Oral
    Indication: Osteoarthritis
    Start date: 2007-06-14
    End date: 2007-07-05

Naproxen
    Dosage: twice daily
    Administration route: Oral
    Indication: Osteoarthritis
    Start date: 2007-06-14
    End date: 2007-07-05

Other drugs received by patient: Calcium; Magnesium Sulfate; Zinc; Hydrochlorothiazide; Levothyroxine Sodium; Omega 3; Spironolactone; Vitamin B-12; Zetia; Actonel; Klor-CON

Adverse event in 55 year old receiving Naproxen

Reported by a physician from United States on 2007-10-29

Patient: 55 year old

Adverse reactions / side effects: Completed Suicide

Adverse event resulted in: death

Suspect drug(s):
Naproxen
    Dosage: route: ingestion.
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Aspirin
    Dosage: route: ingestion.
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Carisoprodol
    Dosage: route: ingestion.
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Adverse event in 63 year old receiving Naproxen

Reported by a physician from United States on 2007-10-29

Patient: 63 year old

Adverse reactions / side effects: Completed Suicide

Adverse event resulted in: death

Suspect drug(s):
Naproxen
    Dosage: route reported as ingestion.
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Ethanol
    Dosage: route reported as ingestion.
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Adverse event in 77 year old receiving Naproxen

Reported by a physician from United States on 2007-10-29

Patient: 77 year old

Adverse reactions / side effects: Completed Suicide

Adverse event resulted in: death

Suspect drug(s):
Naproxen
    Dosage: route reported as ingestion.
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Acetaminophen
    Dosage: route reported as ingestion.
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Adverse event in receiving Naproxen

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2007-10-29

Patient:

Adverse reactions / side effects: Duodenal Ulcer, Gastric Ulcer

Suspect drug(s):
Ibuprofen
Dosage: (df)
Indication: Drug USE FOR Unknown Indication

Naproxen
Dosage: (df)
Indication: Drug USE FOR Unknown Indication

Diclofenac (Diclofenac)
Dosage: (df)
Indication: Drug USE FOR Unknown Indication

Adverse event in 56 year old female receiving Naproxen

Reported by a physician from Norway on 2007-10-24

Patient: 56 year old female

Adverse reactions / side effects: Dyspnoea, Hyponatraemia, Obstructive Airways Disorder, Generalised Oedema

Adverse event resulted in: life threatening event

Suspect drug(s):
Ibux
Indication: Arthralgia
Start date: 2007-08-01

Naproxen
Administration route: Oral
Indication: Arthralgia

Cozaar
    Dosage: 1 df, qd
    Administration route: Oral
    Indication: Hypertension

Diural
    Dosage: 40 mg, qd
    Administration route: Oral
    Indication: Oedema
    Start date: 2007-08-28

Brexidol
Administration route: Oral
Indication: Arthralgia

Voltaren
    Dosage: 50 mg, tid
    Administration route: Oral
    Indication: Arthralgia
    Start date: 2007-08-01

Other drugs received by patient: Pinex Forte; Doxylin; Vival; Noni Juice; Pinex; Fenazon-Koffein

Adverse event in 56 year old female receiving Naproxen

Reported by a health professional (non-physician/pharmacist) from Norway on 2007-10-24

Patient: 56 year old female

Adverse reactions / side effects: Drug Interaction, Hyponatraemia

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Diclofenac Sodium
    Administration route: Oral
    Indication: Arthralgia
    Start date: 2007-08-01

Ibuprofen
    Administration route: Oral
    Indication: Arthralgia
    Start date: 2007-08-01

Naproxen
Administration route: Oral
Indication: Arthralgia

Piroxicam Betadex
Administration route: Oral
Indication: Arthralgia

Furosemide
    Administration route: Oral
    Indication: Oedema
    Start date: 2007-08-28

Hyzaar
Administration route: Oral
Indication: Hypertension

Other drugs received by patient possibly interacting with the suspect drug:
Doxycycline Hyclate
Indication: Pneumonia
Start date: 2007-08-28

Other drugs received by patient: Antipyrine and Caffeine; Acetaminophen and Codeine Phosphate; Acetaminophen; Noni; Diazepam

Adverse event in 48 year old female receiving Naproxen

Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-23

Patient: 48 year old female

Adverse reactions / side effects: Dyspnoea, Anaphylactic Reaction, Oedema Mouth

Adverse event resulted in: hospitalization

Suspect drug(s):
Chantix
Administration route: Oral
Indication: Smoking Cessation Therapy

Naproxen
Start date: 2006-10-01

Adverse event in 35 year old female receiving Naproxen

Reported by a consumer/non-health professional from United States on 2007-10-22

Patient: 35 year old female, weighing 59.0 kg (129.7 pounds)

Adverse reactions / side effects: Gastrointestinal Disorder, Gastric Ulcer

Suspect drug(s):
Naproxen

Adverse event in 75 year old female receiving Naproxen

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-18

Patient: 75 year old female

Adverse reactions / side effects: Hypersensitivity, Wheezing, Increased Bronchial Secretion, Cough

Adverse event resulted in: disablity

Suspect drug(s):
Naproxen

Other drugs received by patient: Atenolol (Con.); Diclofenac (Con.); Doxycycline (Con.); Indapamide Hemihydrate (Con.); Omeprazole (Con.)

Adverse event in 62 year old male receiving Naproxen

Reported by a physician from United States on 2007-10-18

Patient: 62 year old male

Adverse reactions / side effects: Wheezing, Hyperhidrosis, Pallor, Sinus Bradycardia, Weight Increased, Haematocrit Decreased, Crepitations, Oedema, Orthopnoea, Blood Creatinine Increased, Cold Sweat, Blood Urea Increased, Angina Pectoris, Urine Output Decreased, Blood Potassium Increased, Haemodialysis, Haemoglobin Decreased, Syncope

Adverse event resulted in: hospitalization

Suspect drug(s):
Verapamil
Dosage: 360 mg, daily;

Atenolol
Dosage: 25 mg, twice a day;

Clonidine
Dosage: 0.4 mg; weekly; transdermal

Irbesartan
Dosage: 150 mg, twice a day;

Terazosin Hydrochloride
Dosage: 5 mg; daily;

Furosemide
Dosage: 80 mg; daily;

Metolazone
Dosage: 2.5 mg; daily;

Insulin

Naproxen

Potassium Chloride
Dosage: 20 meq; daily;

Adverse event in 59 year old male receiving Naproxen

Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-17

Patient: 59 year old male

Adverse reactions / side effects: Angioedema, Arthralgia, Paraesthesia

Adverse event resulted in: hospitalization

Suspect drug(s):
Lisinopril
    Dosage: 20mg every day po
    Administration route: Oral
    Indication: Hypertension
    Start date: 2007-05-29
    End date: 2007-09-16

Naproxen

Adverse event in 75 year old female receiving Naproxen

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-15

Patient: 75 year old female, weighing 96.0 kg (211.2 pounds)

Adverse reactions / side effects: Hypersensitivity, Wheezing, Increased Bronchial Secretion, Cough

Adverse event resulted in: disablity

Suspect drug(s):
Naproxen

Other drugs received by patient: Atenolol; Diclofenac Sodium; Doxycycline; Indapamide; Omeprazole

Adverse event in 24 year old male receiving Naproxen

Reported by a pharmacist from United States on 2007-10-12

Patient: 24 year old male

Adverse reactions / side effects: Gastrointestinal Haemorrhage, Gastric Haemorrhage

Adverse event resulted in: hospitalization

Suspect drug(s):
Naproxen
    Dosage: 500mg bid po
    Administration route: Oral
    Indication: Pain
    Start date: 2007-08-24
    End date: 2007-08-25

Ibuprofen
    Dosage: 800mg qid po
    Administration route: Oral
    Start date: 2007-08-21
    End date: 2007-08-25

Adverse event in female receiving Naproxen

Reported by a health professional (non-physician/pharmacist) from Hungary on 2007-10-12

Patient: female

Adverse reactions / side effects: Venous Thrombosis Limb

Adverse event resulted in: hospitalization

Suspect drug(s):
Tramadol HCL
Indication: Drug USE FOR Unknown Indication

Panitumumab
Indication: Colorectal Cancer

Perindopril Erbumine
Indication: Drug USE FOR Unknown Indication

Famotidine
Indication: Drug USE FOR Unknown Indication

Naproxen
Indication: Drug USE FOR Unknown Indication

Adverse event in 79 year old male receiving Naproxen

Reported by a pharmacist from United States on 2007-10-12

Patient: 79 year old male

Adverse reactions / side effects: Gastric Ulcer Perforation, Gastric Haemorrhage

Adverse event resulted in: death

Suspect drug(s):
Naproxen

Adverse event in 81 year old female receiving Naproxen

Reported by a physician from Australia on 2007-10-10

Patient: 81 year old female

Adverse reactions / side effects: Abdominal Pain, Renal Impairment, Duodenal Ulcer, Constipation, Melaena

Adverse event resulted in: hospitalization

Suspect drug(s):
Fosamax
Administration route: Oral

Naproxen

Other drugs received by patient: Furosemide; Potassium Chloride; Terbutaline Sulfate; Budesonide

Adverse event in 55 year old male receiving Naproxen

Reported by a pharmacist from United States on 2007-10-10

Patient: 55 year old male

Adverse reactions / side effects: Haemoglobin Decreased, Haematochezia, Abdominal Discomfort, Gastrointestinal Haemorrhage, Haematocrit Decreased, Gastric Haemorrhage

Adverse event resulted in: hospitalization

Suspect drug(s):
Naproxen

Adverse event in female receiving Naproxen

Reported by a individual with unspecified qualification from Hungary on 2007-10-09

Patient: female

Adverse reactions / side effects: Venous Thrombosis Limb

Adverse event resulted in: hospitalization

Suspect drug(s):
Perindopril Erbumine
    Dosage: daily dose: 8 milligram(s)
    Administration route: Oral
    Indication: Ill-Defined Disorder

Panitumumab
    Dosage: daily dose: 432 milligram(s)
    Indication: Colorectal Cancer
    Start date: 2007-03-01
    End date: 2007-03-01

Famotidine
Dosage: daily dose: 40 milligram(s)
Indication: Ill-Defined Disorder

Tramadol HCL
Dosage: daily dose: 100 milligram(s)
Indication: Ill-Defined Disorder

Naproxen
    Dosage: daily dose: 2 dosage form
    Administration route: Oral
    Indication: Ill-Defined Disorder

Adverse event in 56 year old male receiving Naproxen

Reported by a pharmacist from United States on 2007-10-03

Patient: 56 year old male

Adverse reactions / side effects: Haemorrhage, Haematemesis

Adverse event resulted in: hospitalization

Suspect drug(s):
Naproxen

Adverse event in 33 year old male receiving Naproxen

Reported by a pharmacist from United States on 2007-10-03

Patient: 33 year old male

Adverse reactions / side effects: Gastrointestinal Haemorrhage, Paradoxical Drug Reaction, Anaemia, Dizziness, Procedural Complication, Menorrhagia, Gastritis

Adverse event resulted in: hospitalization

Suspect drug(s):
Naproxen
    Dosage: 220mg po
    Administration route: Oral
    Indication: Headache
    Start date: 2007-09-09
    End date: 2007-09-16

Acetaminophen / Aspirin
    Dosage: po
    Administration route: Oral
    Start date: 2007-09-09
    End date: 2007-09-16

Adverse event in 70 year old male receiving Naproxen

Reported by a physician from Japan on 2007-07-31

Patient: 70 year old male, weighing 60.0 kg (132.0 pounds)

Adverse reactions / side effects: Sepsis, Liver Disorder, Stevens-Johnson Syndrome

Adverse event resulted in: death

Suspect drug(s):
Naproxen
    Administration route: Oral
    Indication: Pyrexia
    Start date: 2006-09-20
    End date: 2006-09-26

Rohypnol
    Administration route: Oral
    Start date: 2006-09-13
    End date: 2006-09-15

Rohypnol
    Administration route: Oral
    Start date: 2006-09-18
    End date: 2006-09-19

Rohypnol
    Administration route: Oral
    Start date: 2006-09-21
    End date: 2006-09-21

Rohypnol
    Administration route: Oral
    Start date: 2006-09-23
    End date: 2006-09-26

Cercine
    Administration route: Oral
    Indication: Convulsion Prophylaxis
    Start date: 2006-09-24
    End date: 2006-09-26

Perdipine
    Dosage: dose increased or decreased based on blood pressure, on an as needed basis
    Indication: Hypertension
    Start date: 2006-08-24
    End date: 2006-08-24

Amoban
    Dosage: drug name: amoban tablets 7.5.
    Administration route: Oral
    Start date: 2006-09-20
    End date: 2006-09-20

Amoban
    Administration route: Oral
    Start date: 2006-09-22
    End date: 2006-09-23

Amoban
    Administration route: Oral
    Start date: 2006-09-25
    End date: 2006-09-25

Magmitt
    Administration route: Oral
    Indication: Constipation
    Start date: 2006-08-29
    End date: 2006-09-26

Phenobarbital TAB
    Administration route: Oral
    Indication: Convulsion Prophylaxis
    Start date: 2006-08-28
    End date: 2006-09-23

Myslee
    Administration route: Oral
    Start date: 2006-08-22
    End date: 2006-08-22

Myslee
    Administration route: Oral
    Start date: 2006-08-31
    End date: 2006-08-31

Myslee
    Administration route: Oral
    Start date: 2006-09-23
    End date: 2006-09-23

Ubretid
    Administration route: Oral
    Indication: Neurogenic Bladder
    Start date: 2006-09-08
    End date: 2006-09-29

Spelear
    Administration route: Oral
    Indication: Sputum Retention
    Start date: 2006-09-14
    End date: 2006-09-24

Selbex
    Administration route: Oral
    Indication: Gastritis
    Start date: 2006-09-24
    End date: 2006-09-24

Lansoprazole
    Administration route: Oral
    Indication: Gastric Ulcer
    Start date: 2006-08-24
    End date: 2006-08-24

Lansoprazole
    Administration route: Oral
    Start date: 2006-09-06
    End date: 2006-09-29

Tegretol
    Administration route: Oral
    Indication: Wound Complication
    Start date: 2006-09-22
    End date: 2006-09-23

Aspirin
    Administration route: Oral
    Indication: Cerebral Infarction
    Start date: 2006-08-30
    End date: 2006-09-30

Polaramine
    Administration route: Oral
    Indication: Pruritus
    Start date: 2006-09-23
    End date: 2006-09-23

Loxonin
    Administration route: Oral
    Indication: Wound Complication
    Start date: 2006-09-18
    End date: 2006-09-20

Loxonin
    Administration route: Oral
    Start date: 2006-09-23
    End date: 2006-09-24

Voltaren
    Indication: Wound Complication
    Start date: 2006-08-24
    End date: 2006-08-24

Voltaren
Dosage: form: rectal suppository.
Start date: 2006-09-04

Voltaren
Start date: 2006-09-17
End date: 2006-09-17

Voltaren
Start date: 2006-09-18
End date: 2006-09-19

Voltaren
Start date: 2006-09-20
End date: 2006-09-22

Voltaren
Start date: 2006-09-23
End date: 2006-09-23

Ketoprofen
    Dosage: form: tape. dose: adjusted 10 x 14 cm.
    Indication: Wound Complication
    Start date: 2006-09-17

Laxoberon
    Dosage: dose: as needed
    Administration route: Oral
    Indication: Constipation
    Start date: 2006-09-02

Rinderon-VG
    Dosage: dose: as needed
    Administration route: Topical
    Indication: Rash
    Start date: 2006-09-18

Solu-Medrol
    Indication: Asthma
    Start date: 2006-09-20
    End date: 2006-09-21

Aminofluid
    Indication: Fluid Replacement
    Start date: 2006-09-25
    End date: 2006-09-26

Pasil
    Indication: Infection
    Start date: 2006-09-20
    End date: 2006-09-20

Finibax
    Indication: Infection
    Start date: 2006-09-19
    End date: 2006-09-20

Flumarin
    Indication: Infection
    Start date: 2006-09-17
    End date: 2006-09-17

NEO-Minophagen C
    Indication: Hepatic Function Abnormal
    Start date: 2006-09-01
    End date: 2006-09-11

NEO-Minophagen C
Start date: 2006-09-25
End date: 2006-09-27

NEO-Minophagen C
Start date: 2006-09-29
End date: 2006-10-12

Sennoside
    Administration route: Oral
    Indication: Constipation
    Start date: 2006-08-22
    End date: 2006-08-22

Humulin 70 / 30
    Indication: Hyperglycaemia
    Start date: 2006-08-23
    End date: 2006-08-24

Mobic
    Administration route: Oral
    Start date: 2006-08-24
    End date: 2006-08-24

Albumin (Human)
Start date: 2006-08-24
End date: 2006-08-24

1 Suspected Drug
    Dosage: drug name reported as anapeine (ropivacaine)
    Start date: 2006-08-24
    End date: 2006-08-26

Omeprazole
Start date: 2006-08-24
End date: 2006-08-30

1 Suspected Drug
    Dosage: drug name reported as pansporin (cefotiam hydrochloride)
    Indication: Infection Prophylaxis
    Start date: 2006-08-24
    End date: 2006-08-26

Cataclot
    Indication: Cerebral Infarction
    Start date: 2006-08-24
    End date: 2006-08-24

Multivitamin Additive
    Dosage: total daily dose =1 vial
    Indication: Vitamin Supplementation
    Start date: 2006-08-24
    End date: 2006-08-30

Novo-Heparin
    Indication: Drug USE FOR Unknown Indication
    Start date: 2006-08-24
    End date: 2006-08-27

Bisolvon
    Dosage: taken on an as needed basis
    Start date: 2006-08-24
    End date: 2006-08-24

Bisolvon
    Dosage: taken on an as needed basis
    Start date: 2006-08-29
    End date: 2006-09-04

Radicut
    Indication: Cerebral Infarction
    Start date: 2006-08-24
    End date: 2006-09-03

Amino Acid INJ
    Indication: Nutritional Support
    Start date: 2006-08-24
    End date: 2006-08-25

Other drugs received by patient: Unspecified Drug

Adverse event in 70 year old male receiving Naproxen

Reported by a physician from Japan on 2007-07-31

Patient: 70 year old male

Adverse reactions / side effects: Stevens-Johnson Syndrome

Adverse event resulted in: death

Suspect drug(s):
Perdipine
    Dosage: daily dose reported: increased or decreased based on blood pressure, on an as needed basis.
    Indication: Hypertension
    Start date: 2006-08-24
    End date: 2006-08-24

Naproxen
    Administration route: Oral
    Indication: Pyrexia
    Start date: 2006-09-20
    End date: 2006-09-26