|
Index of reports
> Cases resulting in a serious event (1131)
> Cases with Sepsis (57)
Below is the selection of adverse event reports related to Methotrexate that includes cases resulting in a serious event where reactions include sepsis.
Reports 1 - 25 of 57 Next >>
Adverse event in male receiving Methotrexate
Reported by a individual with unspecified qualification from United Kingdom on 2007-10-31
Patient: male
Adverse reactions / side effects: Sepsis
Adverse event resulted in: death
Suspect drug(s):
Cisplatin
Dosage: 50 mg/m2, over 4th days 3 and 4
Indication: Germ Cell Cancer
Etoposide
Dosage: 90 mg/m2, days 1-4 over 2h)
Indication: Germ Cell Cancer
Dactinomycin
Dosage: 1 mg/m2
Indication: Germ Cell Cancer
Methotrexate
Indication: Germ Cell Cancer
Adverse event in receiving Methotrexate
Reported by a individual with unspecified qualification from United Kingdom on 2007-10-31
Patient:
Adverse reactions / side effects: Drug Toxicity, Intra-Abdominal Haemorrhage, Sepsis, Febrile Neutropenia
Adverse event resulted in: death
Suspect drug(s):
Cisplatin
Dosage: 50 mg/m2, over 4h days 3 and 4
Indication: Germ Cell Cancer
Etoposide
Dosage: 90 mg/m2, days 1-4 over 2h
Indication: Germ Cell Cancer
Dactinomycin
Dosage: 1 mg/m2
Indication: Germ Cell Cancer
Methotrexate
Indication: Germ Cell Cancer
Adverse event in receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-30
Patient:
Adverse reactions / side effects: Sepsis
Adverse event resulted in: death
Suspect drug(s):
Etoposide
Dosage: 90mg/m2days 1-4 over2h:methotrexate loading dose over 30min followed by 12hinfusion
Indication: Germ Cell Cancer
Cisplatin
Dosage: 50mg/m2 over 4 h days 3 and 4.
Indication: Germ Cell Cancer
Methotrexate
Indication: Germ Cell Cancer
Dactinomycin
Dosage: 1(mg/m2)day
Indication: Germ Cell Cancer
Other drugs received by patient: Carboplatin; Neupogen; Leucovorin
Adverse event in 65 year old male receiving Methotrexate
Reported by a consumer/non-health professional from United States on 2007-10-24
Patient: 65 year old male, weighing 81.6 kg (179.6 pounds)
Adverse reactions / side effects: White Blood Cell Count Decreased, Colon Gangrene, Haemorrhoidal Haemorrhage, Abdominal Pain Upper, Bone Marrow Disorder, Gastrointestinal Infection, Intestinal Perforation, Sepsis, Platelet Count Decreased, Epistaxis
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Methotrexate
Adverse event in receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-24
Patient:
Adverse reactions / side effects: Sepsis
Adverse event resulted in: death
Suspect drug(s):
Cisplatin
Indication: Germ Cell Cancer
Etoposide
Indication: Germ Cell Cancer
Methotrexate
Indication: Germ Cell Cancer
Dactinomycin
Indication: Germ Cell Cancer
Other drugs received by patient: Neupogen
Adverse event in receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-24
Patient:
Adverse reactions / side effects: Sepsis
Adverse event resulted in: death
Suspect drug(s):
Etoposide
Indication: Germ Cell Cancer
Cisplatin
Indication: Germ Cell Cancer
Methotrexate
Indication: Germ Cell Cancer
Dactinomycin
Indication: Germ Cell Cancer
Other drugs received by patient: Carboplatin; Neupogen; Leucovorin
Adverse event in 50 year old female receiving Methotrexate
Reported by a individual with unspecified qualification from Japan on 2007-10-23
Patient: 50 year old female
Adverse reactions / side effects: Bone Marrow Transplant Rejection, Stomatitis, Vomiting, Nausea, Ill-Defined Disorder, Stem Cell Transplant, Blood Potassium Decreased, Gamma-Glutamyltransferase Increased, Anorexia, Sepsis, Cytomegalovirus Infection, Pseudomembranous Colitis, Neutropenia, Mucous Membrane Disorder
Adverse event resulted in: life threatening event, hospitalization, disablity
Suspect drug(s):
Busulfan (Busulfan)
Dosage: 26.4 ml;qd;iv
Indication: Stem Cell Transplant
Start date: 2006-11-09
End date: 2006-11-10
Methotrexate
Dosage: 26.4 ml;qd;iv
Indication: Prophylaxis Against Graft Versus Host Disease
Other drugs received by patient: Fludarabine Phosphate; Phenytoin; Neupogen
Adverse event in receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-23
Patient:
Adverse reactions / side effects: Sepsis
Adverse event resulted in: death
Suspect drug(s):
Etoposide
Indication: Germ Cell Cancer
Cisplatin
Indication: Germ Cell Cancer
Methotrexate
Indication: Germ Cell Cancer
Actinomycin-D
Indication: Germ Cell Cancer
Adverse event in receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-22
Patient:
Adverse reactions / side effects: Sepsis
Adverse event resulted in: death
Suspect drug(s):
Etoposide
Indication: Germ Cell Cancer
Cisplatin
Indication: Germ Cell Cancer
Carboplatin
Methotrexate
Indication: Germ Cell Cancer
Dactinomycin
Indication: Germ Cell Cancer
Neupogen
Folinic Acid
Adverse event in 60 year old female receiving Methotrexate
Reported by a individual with unspecified qualification from Taiwan, Province of China on 2007-10-19
Patient: 60 year old female
Adverse reactions / side effects: Urinary Incontinence, Disseminated Intravascular Coagulation, Muscular Weakness, Pancytopenia, Hypoaesthesia, Nosocomial Infection, Staphylococcal Infection, Oral Candidiasis, Sensory Disturbance, Sepsis, Escherichia Infection, Spinal Cord Disorder, Myelopathy
Suspect drug(s):
Methotrexate
Dosage: dose: 12 mg
Indication: B-Cell Lymphoma
Start date: 1993-09-24
End date: 1994-02-17
Methotrexate
Dosage: dose: 1 g/m2 sytemically
Start date: 1993-10-16
End date: 1993-10-16
Hydrocortisone
Indication: B-Cell Lymphoma
Start date: 1993-09-24
End date: 1994-02-17
Other drugs received by patient: Cytarabine; Cytarabine; Rituximab; Rituximab; Radiation Therapy
Adverse event in 77 year old female receiving Methotrexate
Reported by a individual with unspecified qualification on 2007-10-19
Patient: 77 year old female
Adverse reactions / side effects: Agranulocytosis, Sepsis
Suspect drug(s):
Methotrexate
Adverse event in female receiving Methotrexate
Reported by a individual with unspecified qualification from United States on 2007-10-12
Patient: female, weighing 75.0 kg (165.0 pounds)
Adverse reactions / side effects: Blood Bilirubin Increased, Disseminated Cytomegaloviral Infection, Hypotension, Pseudomonas Infection, Culture Urine Positive, Respiratory Distress, Acute Graft Versus Host Disease in Liver, Soft Tissue Infection, Respiratory Failure, Sepsis, Sputum Culture Positive, Bradycardia
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Cyclosporine
Dosage: 188 mg
Methotrexate
Dosage: 41 mg
Methoxsalen
Dosage: 180.6 mcg
Cellcept
Dosage: 500 mg
Pentostatin
Dosage: 13 mg
Adverse event in receiving Methotrexate
Reported by a individual with unspecified qualification from United Kingdom on 2007-10-11
Patient:
Adverse reactions / side effects: Sepsis
Adverse event resulted in: death
Suspect drug(s):
Cisplatin
Dosage: (50 mg/m2)
Indication: Germ Cell Cancer
Etoposide
Dosage: (90 mg/m2)
Indication: Germ Cell Cancer
Dactinomycin
Dosage: (1 mg/m2)
Indication: Germ Cell Cancer
Methotrexate
Indication: Germ Cell Cancer
Adverse event in receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-05
Patient:
Adverse reactions / side effects: Sepsis
Adverse event resulted in: death
Suspect drug(s):
Etoposide
Indication: Germ Cell Cancer
Cisplatin
Indication: Germ Cell Cancer
Methotrexate
Indication: Germ Cell Cancer
Actinomycin-D
Indication: Germ Cell Cancer
Adverse event in male receiving Methotrexate
Reported by a individual with unspecified qualification from United States on 2007-10-03
Patient: male, weighing 22.4 kg (49.3 pounds)
Adverse reactions / side effects: Clostridium Difficile Toxin Test Positive, Streptococcal Identification Test Positive, Hypotension, Pseudomonas Infection, Caecitis, Capillary Leak Syndrome, Cardio-Respiratory Arrest, Respiratory Failure, Sepsis, Blood Culture Positive, Blood Pressure Abnormal
Adverse event resulted in: hospitalization
Suspect drug(s):
Cytarabine
Dosage: 70 mg given intrathecally
Dexamethasone 0.5mg TAB
Dosage: 71.5 mg given q day bid
Methotrexate
Dosage: 12 mg given intrathecally
Adverse event in 63 year old female receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-01
Patient: 63 year old female, weighing 60.0 kg (132.0 pounds)
Adverse reactions / side effects: Sepsis, Acute Respiratory Distress Syndrome, Pancytopenia
Adverse event resulted in: death, life threatening event, hospitalization, disablity
Suspect drug(s):
Enbrel
Indication: Drug USE FOR Unknown Indication
Start date: 2006-09-08
End date: 2007-07-29
Methotrexate
Administration route: Oral
Start date: 2002-07-17
End date: 2007-07-29
Other drugs received by patient: Indomethacin; Calcium with Vitamin D; Ferrous Sulfate TAB; Ranitidine; Frusemide; Atenolol; Metformin HCL; Ramipril; Folic Acid
Adverse event in 40 year old female receiving Methotrexate
Reported by a individual with unspecified qualification from Japan on 2007-07-23
Patient: 40 year old female
Adverse reactions / side effects: Stomatitis, Acute Graft Versus Host Disease, Diarrhoea, Sepsis, Pharyngeal Erythema
Adverse event resulted in: life threatening event
Suspect drug(s):
Busulfan (Busulfan)
Dosage: iv
Indication: Stem Cell Transplant
Start date: 2007-01-05
End date: 2007-01-06
Cyclophosphamide
Dosage: 3200 mg; qd; iv
Indication: Stem Cell Transplant
Start date: 2007-01-09
End date: 2007-01-10
Methotrexate
Indication: Drug USE FOR Unknown Indication
Other drugs received by patient: Valproate Sodium; Filgrastim; Cyclosporine
Adverse event in female receiving Methotrexate
Reported by a individual with unspecified qualification from United Kingdom on 2007-07-18
Patient: female, weighing 71.0 kg (156.2 pounds)
Adverse reactions / side effects: Rheumatoid Arthritis, Cardio-Respiratory Arrest, Drug Therapy, Diarrhoea, Sepsis, Acute Respiratory Distress Syndrome
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Humira
Indication: Rheumatoid Arthritis
Start date: 2006-10-28
End date: 2006-11-17
Methotrexate
Indication: Drug USE FOR Unknown Indication
Other drugs received by patient: Prednisolone
Adverse event in 50 year old female receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from Japan on 2007-07-17
Patient: 50 year old female
Adverse reactions / side effects: Stomatitis, Nausea, Malaise, Diarrhoea, Anorexia, Sepsis, Cytomegalovirus Infection, Pseudomembranous Colitis
Adverse event resulted in: life threatening event
Suspect drug(s):
Busulfan (Busulfan)
Dosage: 26.4 ml;qd; iv
Indication: Stem Cell Transplant
Start date: 2006-11-09
End date: 2006-11-10
Methotrexate
Indication: Prophylaxis Against Graft Versus Host Disease
Other drugs received by patient: Fludarabine Phosphate; Phenytoin; Neupogen
Adverse event in female receiving Methotrexate
Reported by a physician from Germany on 2007-07-12
Patient: female, weighing 90.0 kg (198.0 pounds)
Adverse reactions / side effects: Heparin-Induced Thrombocytopenia, Pancytopenia, Bile Duct Cancer, Pyrexia, Multi-Organ Failure, Pancreatitis Necrotising, Sepsis, Femoral Neck Fracture, Ventricular Fibrillation
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Enbrel
Indication: Rheumatoid Arthritis
Start date: 2006-02-01
End date: 2006-11-24
Methotrexate
Administration route: Oral
Indication: Rheumatoid Arthritis
Start date: 2003-03-01
End date: 2005-10-01
Methotrexate
Dosage: unknown
Administration route: Oral
Start date: 2000-06-01
End date: 2003-03-01
Methotrexate
Administration route: Oral
Start date: 2006-01-01
End date: 2007-03-01
Other drugs received by patient: Prednisolone; Marcumar; Bisoprolol; Xipamide; Morphine; Novodigal; Osteoplus; Spironolactone; Simvastatin; Molsidomine - Slow Release
Adverse event in 52 year old male receiving Methotrexate
Reported by a individual with unspecified qualification from Germany on 2007-07-12
Patient: 52 year old male
Adverse reactions / side effects: Multi-Organ Failure, Sepsis
Adverse event resulted in: death
Suspect drug(s):
Methotrexate
Adverse event in 51 year old female receiving Methotrexate
Reported by a individual with unspecified qualification from Germany on 2007-07-12
Patient: 51 year old female
Adverse reactions / side effects: Multi-Organ Failure, Sepsis
Adverse event resulted in: death
Suspect drug(s):
Methotrexate
Adverse event in 58 year old female receiving Methotrexate
Reported by a health professional (non-physician/pharmacist) from Japan on 2007-06-27
Patient: 58 year old female
Adverse reactions / side effects: Bedridden, Guillain-Barre Syndrome, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Acute Graft Versus Host Disease, Muscular Weakness, Quadriplegia, Stenotrophomonas Infection, Chronic Graft Versus Host Disease, Hypoaesthesia, Erythema, Nerve Conduction Studies Abnormal, CSF Protein Increased, Diarrhoea, Sepsis, Areflexia
Suspect drug(s):
Cyclosporine
Indication: Stem Cell Transplant
Methotrexate
Indication: Stem Cell Transplant
Adverse event in 75 year old female receiving Methotrexate
Reported by a individual with unspecified qualification from Germany on 2007-06-27
Patient: 75 year old female
Adverse reactions / side effects: Pneumonia, Glossitis, Pancytopenia, Drug Interaction, Odynophagia, Sepsis, Bone Marrow Failure, Bone Marrow Toxicity, Oral Mucosal Petechiae
Adverse event resulted in: death
Suspect drug(s):
Methotrexate
Dosage: 15 mg weekly;
Indication: Arthropathy
Methotrexate
Dosage: 15 mg weekly;
Indication: Rheumatoid Arthritis
Aminoglycoside
Adverse event in 25 year old male receiving Methotrexate
Reported by a physician from Australia on 2007-06-14
Patient: 25 year old male
Adverse reactions / side effects: Gastrointestinal Haemorrhage, Graft Versus Host Disease, Cerebral Haemorrhage, Stem Cell Transplant, Bone Marrow Disorder, Myelopathy, Haematuria, Febrile Neutropenia, Paraesthesia, Paralysis Flaccid, CSF Protein Increased, Cerebral Infarction, Sepsis, Sensory Disturbance, NO Therapeutic Response, BK Virus Infection, Areflexia
Adverse event resulted in: hospitalization, disablity
Suspect drug(s):
Methotrexate
Indication: non-Hodgkin's Lymphoma
Start date: 2003-01-01
End date: 2003-07-01
Methotrexate
Dosage: 12 mg it
Indication: non-Hodgkin's Lymphoma
Start date: 2003-01-10
Methotrexate
Dosage: 12 mg it
Indication: non-Hodgkin's Lymphoma
Start date: 2003-03-12
Methotrexate
Dosage: 12 mg it
Indication: non-Hodgkin's Lymphoma
Start date: 2003-06-09
Methotrexate
Dosage: 12 mg it
Indication: non-Hodgkin's Lymphoma
Start date: 2003-10-18
Cytarabine
Indication: non-Hodgkin's Lymphoma
Start date: 2003-01-01
End date: 2003-07-01
Cytarabine
Dosage: 100 mg it
Indication: non-Hodgkin's Lymphoma
Start date: 2003-01-15
Cytarabine
Cytarabine
Dosage: 100 mg it
Start date: 2003-02-17
Cytarabine
Dosage: 100 mg it
Start date: 2003-12-19
Other drugs received by patient: Cyclophosphamide; Vincristine; Doxorubicin HCL; Dexamethasone 0.5mg TAB; Radiotherapy; Idarubicin HCL; Fludarabine Phosphate; Multivitamin; Antibiotics
Page 1 Next >>
|
