Lorazepam (Lorazepam) - Adverse Event Reports - Other Serious Reactions

Suicide Attempt (19),  Toxic Epidermal Necrolysis (13),  Confusional State (10),  Drug Ineffective (10),  Intentional Overdose (10),  Agitation (9),  Somnolence (9),  Drug Exposure During Pregnancy (7),  Vomiting (5),  Sedation (5)

Adverse event in 68 year old male receiving Lorazepam

Reported by a consumer/non-health professional from Spain on 2007-10-31

Patient: 68 year old male

Adverse reactions / side effects: Atrial Fibrillation, Drug Interaction

Adverse event resulted in: life threatening event

Suspect drug(s):
Atrovent
    Dosage: 1500mcg per day
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-24

Bisoprolol Fumarate
    Dosage: 25mg per day
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-23

Ciprofloxacin HCL
    Dosage: 800mg per day
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-19

Clexane
    Dosage: 80mg per day
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-24

Flumil
    Dosage: 600mg per day
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-18

Fortam
    Dosage: 6g per day
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-19

Lorazepam
    Dosage: 1mg per day
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-10

Metoclopramide HCL
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-16

Omeprazole
    Dosage: 20mg per day
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-23

Renitec
    Dosage: 5mg per day
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-19

Termalgin
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-08-23

Ventolin
    Dosage: 6ml per day
    Indication: Laryngeal Neoplasm
    Start date: 2007-08-24
    End date: 2007-08-24

Adverse event in male receiving Lorazepam

Reported by a health professional (non-physician/pharmacist) from Germany on 2007-10-30

Patient: male

Adverse reactions / side effects: Intentional Overdose, Suicide Attempt, Somnolence

Suspect drug(s):
Lorazepam
    Dosage: 10 mg; daily; oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-10-13

Seroquel
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-10-13

Venlafaxine HCL
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-10-13

Zopiclodura (Zopiclone)
    Dosage: 7.5 mg; oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-10-13

Adverse event in 42 year old receiving Lorazepam

Reported by a physician from United States on 2007-10-29

Patient: 42 year old

Adverse reactions / side effects: Respiratory Arrest, Intentional Drug Misuse, Cardiac Arrest

Adverse event resulted in: death

Suspect drug(s):
Acetaminophen
    Dosage: acute exposure. route: ingestion
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Clonazepam
    Dosage: acute exposure. route: ingestion
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Lorazepam
    Dosage: acute exposure. route: ingestion
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Adverse event in 69 year old male receiving Lorazepam

Reported by a individual with unspecified qualification from Netherlands on 2007-10-23

Patient: 69 year old male

Adverse reactions / side effects: Cerebral Infarction

Suspect drug(s):
Lorazepam

Adverse event in 72 year old male receiving Lorazepam

Reported by a pharmacist from Canada on 2007-10-18

Patient: 72 year old male

Adverse reactions / side effects: Dystonia, Sedation, Respiratory Arrest, Obstructive Airways Disorder, Sleep Apnoea Syndrome

Suspect drug(s):
APO-Haloperidol
    Administration route: Oral

Lorazepam

Risperidone

Seroquel
    Administration route: Oral

Other drugs received by patient: Advair Diskus 100 / 50; Benztropine; Bisoprolol Fumarate; Crestor; Aspirin 10gr Timed Disintegration TAB; Finasteride; Ipratropium Bromide; Levothyroxine Sodium; Ramipril; Salbutamol; Warfarin Sodium

Adverse event in 55 year old female receiving Lorazepam

Reported by a individual with unspecified qualification from United States on 2007-10-18

Patient: 55 year old female, weighing 73.5 kg (161.7 pounds)

Adverse reactions / side effects: Panic Attack, Nausea, Impaired Work Ability, Insomnia, Drug Withdrawal Syndrome, Hypertension

Suspect drug(s):
Lorazepam
    Indication: Insomnia
    Start date: 2007-09-19
    End date: 2007-10-12

Lorazepam
    Indication: Pain
    Start date: 2007-09-19
    End date: 2007-10-12

Adverse event in female receiving Lorazepam

Reported by a individual with unspecified qualification from United States on 2007-10-18

Patient: female, weighing 68.0 kg (149.6 pounds)

Adverse reactions / side effects: Obstruction Gastric, Drug Ineffective, Deafness, Gastrointestinal Inflammation, Somnolence, Constipation, Myalgia, Electroencephalogram Abnormal, Blood Sodium Increased, Myocardial Infarction, Blood Sodium Decreased, Gastrointestinal Obstruction, Muscle Spasms, Fluid Retention, Middle Ear Effusion, Cerebrovascular Accident, Convulsion, Breast Swelling, Hypertension, Muscle Disorder

Suspect drug(s):
Lorazepam

Other drugs received by patient: Vitamins; Calcium

Adverse event in 19 year old male receiving Lorazepam

Reported by a pharmacist from Canada on 2007-10-17

Patient: 19 year old male

Adverse reactions / side effects: Vision Blurred, Amnesia

Suspect drug(s):
Ativan

Bupropion HCL

Effexor

Lorazepam

Seroquel
    Administration route: Oral

Wellbutrin

Adverse event in male receiving Lorazepam

Reported by a consumer/non-health professional from United States on 2007-10-11

Patient: male, weighing 86.4 kg (190.0 pounds)

Adverse reactions / side effects: Drug Ineffective, Lung Neoplasm Malignant, Disturbance in Attention, Mental Disorder, Bladder Distension, Amnesia, Feeling Abnormal

Suspect drug(s):
Chantix
    Indication: Smoking Cessation Therapy
    Start date: 2007-01-01
    End date: 2007-01-01

Lithium
    Indication: Mental Disorder

Lorazepam
    Indication: Sleep Disorder

Risperdal

Other drugs received by patient: Vitamins

Adverse event in female receiving Lorazepam

Reported by a health professional (non-physician/pharmacist) from Germany on 2007-10-09

Patient: female

Adverse reactions / side effects: Fatigue, Intentional Overdose, Hypotension, Suicide Attempt, Circulatory Collapse, Somnolence

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Lorazepam

Adverse event in male receiving Lorazepam

Reported by a health professional (non-physician/pharmacist) from Italy on 2007-10-08

Patient: male

Adverse reactions / side effects: Agitation, Drug Exposure During Pregnancy, Premature Baby, Insomnia, Agitation Neonatal

Suspect drug(s):
Elopram(citalopram) Unknown,40mg / ML
    Dosage: transplacental
    Start date: 2006-12-12
    End date: 2007-03-01

Lorazepam
    Dosage: transplacental
    Start date: 2006-11-28
    End date: 2007-03-01

Other drugs received by patient: Paroxetine

Adverse event in male receiving Lorazepam

Reported by a consumer/non-health professional from United States on 2007-10-06

Patient: male, weighing 68.0 kg (149.6 pounds)

Adverse reactions / side effects: Agitation, Confusional State, Speech Disorder, Abnormal Dreams, Dizziness, Mood Swings, Psychomotor Hyperactivity, Vomiting, Sensation of Heaviness, Myopia, Drug Withdrawal Syndrome, Tremor, Irritability, Emotional Distress, Arthralgia, Mental Disorder

Suspect drug(s):
Chantix
    Dosage: text:daily
    Administration route: Oral
    Indication: EX-Smoker

Lorazepam
    Dosage: text:as needed
    Indication: Drug Withdrawal Syndrome

Other drugs received by patient: Crestor; Omacor; Fenofibrate

Adverse event in 58 year old male receiving Lorazepam

Reported by a pharmacist from United States on 2007-10-05

Patient: 58 year old male

Adverse reactions / side effects: Initial Insomnia, Middle Insomnia, Pharmaceutical Product Complaint

Suspect drug(s):
Lorazepam

Adverse event in 62 year old male receiving Lorazepam

Reported by a individual with unspecified qualification from United Kingdom on 2007-10-03

Patient: 62 year old male

Adverse reactions / side effects: Anxiety, Agitation, Intentional Overdose, Psychiatric Symptom, Fear, Suicide Attempt, Drug Withdrawal Syndrome, Drug Dependence, Paraesthesia

Adverse event resulted in: hospitalization

Suspect drug(s):
Alprazolam
    Indication: Depressed Mood

Diazepam
    Indication: Anxiety

Lorazepam
    Indication: Depressed Mood

Lorazepam
    Indication: Anxiety

Temazepam
    Indication: Anxiety

Other drugs received by patient: Fluoxetine; Zopiclone

Adverse event in 59 year old female receiving Lorazepam

Reported by a physician from Japan on 2007-10-02

Patient: 59 year old female

Adverse reactions / side effects: Hepatic Function Abnormal

Suspect drug(s):
Aromasin
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2007-04-23
    End date: 2007-07-09

Lorazepam
    Dosage: daily dose:2mg-freq:cyclic : cyclic
    Administration route: Oral
    Indication: Anxiety
    Start date: 2006-12-01
    End date: 2007-07-09

Adverse event in 58 year old female receiving Lorazepam

Reported by a pharmacist from Germany on 2007-08-17

Patient: 58 year old female

Adverse reactions / side effects: Coma, Suicide Attempt, Multiple Drug Overdose

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Abilify
    Dosage: maximum of 49 tablets taken oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Bayotensin (Nitrendipine)
    Dosage: maximum of 1 tablet (1 dosage forms) oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Citalopram Hydrobromide
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Levothyroxine Sodium
    Dosage: maximum 10 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Lorazepam
    Dosage: maximum 50 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Melperone Hydrochloride
    Dosage: maximum 50 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Memantine HCL
    Dosage: maximum of 100 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Metformin Hydrochloride
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Mirtazapine
    Dosage: maximum 20 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Zopiclone
    Dosage: maximum 20 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Adverse event in 58 year old female receiving Lorazepam

Reported by a physician from Germany on 2007-08-17

Patient: 58 year old female

Adverse reactions / side effects: Coma, Suicide Attempt, Multiple Drug Overdose, Haemodialysis

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Abilify
    Dosage: maximum of 49 tablets taken oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Bayotensin (Nitrendipine)
    Dosage: maximum of 1 tablet (1 dosage forms) oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Citalopram Hydrobromide
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Levothyroxine Sodium
    Dosage: maximum 10 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Lorazepam
    Dosage: maximum 50 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Melperone Hydrochloride
    Dosage: maximum 50 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Memantine HCL
    Dosage: maximum of 100 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Metformin Hydrochloride
    Dosage: oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Mirtazapine
    Dosage: maximum 20 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Zopiclone
    Dosage: maximum 20 tablets oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Adverse event in 58 year old female receiving Lorazepam

Reported by a physician from Germany on 2007-08-16

Patient: 58 year old female

Adverse reactions / side effects: Coma, Suicide Attempt, Multiple Drug Overdose, Haemodialysis

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Abilify
    Dosage: maximum of 49 tablets taken
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Bayotensin (Nitrendipine)
    Dosage: maximum of 1 tablet (1 dosage forms)
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Citalopram Hydrobromide
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Levothyroxine Sodium
    Dosage: maximum 10 tablets
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Lorazepam
    Dosage: maximum 50 tablets
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Melperone Hydrochloride
    Dosage: maximum 50 tablets
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Memantine HCL
    Dosage: maximum of 100 tablets
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Metformin Hydrochloride
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Mirtazapine
    Dosage: maximum 20 tablets
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Zopiclone
    Dosage: maximum 20 tablets
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-07-06

Adverse event in 42 year old male receiving Lorazepam

Reported by a consumer/non-health professional from Germany on 2007-07-26

Patient: 42 year old male

Adverse reactions / side effects: Fatigue, Accommodation Disorder, Motor Dysfunction, Disturbance in Attention, Drug Dependence

Suspect drug(s):
Lorazepam
    Dosage: (0.25 mg qd oral), (0.5 mg qd oral)
    Administration route: Oral
    Indication: Anxiety
    Start date: 2006-09-01

Lorazepam
    Dosage: (0.25 mg qd oral), (0.5 mg qd oral)
    Administration route: Oral
    Indication: Anxiety
    Start date: 2007-05-08

Other drugs received by patient: Fluspirilene; Valerian Extract

Adverse event in 37 year old male receiving Lorazepam

Reported by a pharmacist from United States on 2007-07-23

Patient: 37 year old male, weighing 94.6 kg (208.1 pounds)

Adverse reactions / side effects: Syncope, Pain, Unresponsive TO Stimuli, Condition Aggravated

Adverse event resulted in: hospitalization

Suspect drug(s):
Lorazepam
    Dosage: 1 mg once iv
    Indication: Agitation
    Start date: 2007-05-01
    End date: 2007-05-01

Morphine
    Dosage: 6mg once iv
    Indication: Pain
    Start date: 2007-05-01
    End date: 2007-05-01

Adverse event in female receiving Lorazepam

Reported by a physician from Japan on 2007-07-12

Patient: female, weighing 2.3 kg (5.1 pounds)

Adverse reactions / side effects: Mydriasis, Unresponsive TO Stimuli, Brain Stem Ischaemia, Neonatal Asphyxia, Muscle Tightness, Drug Exposure During Pregnancy, Hypoxia, Apnoea

Suspect drug(s):
Bupivacaine Hydrochloride
    Indication: Drug USE FOR Unknown Indication

Lorazepam
    Dosage: .25mg per day
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-06-12
    End date: 2007-06-19

Paxil
    Dosage: 20mg per day
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-06-06
    End date: 2007-06-19

Adverse event in 41 year old male receiving Lorazepam

Reported by a physician from United Kingdom on 2007-07-05

Patient: 41 year old male

Adverse reactions / side effects: Agitation, Confusional State, Lymphadenopathy, Tinnitus, Chills, Culture Urine Positive, Headache, Pyrexia, Photophobia, Musculoskeletal Stiffness, Blood Creatinine Increased, Oesophageal Ulcer, Pharyngitis, Back Pain, Hiatus Hernia, Pneumonia, Vomiting, Anaemia, Urinary Tract Infection, Stupor, Sepsis, Cytomegalovirus Infection, Respiratory Arrest, Cardiac Arrest, Influenza Like Illness

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Certican
    Dosage: 1 mg, bid
    Administration route: Oral
    Indication: Renal Transplant
    Start date: 2006-09-28
    End date: 2006-10-24

Haloperidol
    Start date: 2006-10-26
    End date: 2006-11-01

Lorazepam
    Start date: 2006-10-26
    End date: 2006-10-27

Midazolam HCL
    Start date: 2006-10-27
    End date: 2006-10-29

Neoral
    Administration route: Oral
    Indication: Renal Transplant
    Start date: 2006-09-28

Olanzapine
    Start date: 2006-10-26

Opioids

Palladone

Other drugs received by patient: Aranesp

Adverse event in female receiving Lorazepam

Reported by a physician from Japan on 2007-07-03

Patient: female, weighing 2.3 kg (5.1 pounds)

Adverse reactions / side effects: Mydriasis, Unresponsive TO Stimuli, Brain Stem Ischaemia, Neonatal Asphyxia, Muscle Tightness, Drug Exposure During Pregnancy, Hypoxia, Apnoea

Suspect drug(s):
Bupivacaine Hydrochloride
    Indication: Drug USE FOR Unknown Indication

Lorazepam
    Dosage: .25mg per day
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-06-12
    End date: 2007-06-19

Paxil
    Dosage: 20mg per day
    Indication: Drug USE FOR Unknown Indication
    Start date: 2007-06-06
    End date: 2007-06-19

Adverse event in 58 year old male receiving Lorazepam

Reported by a individual with unspecified qualification from Germany on 2007-07-03

Patient: 58 year old male

Adverse reactions / side effects: Overdose, Extrasystoles, Gastrointestinal Hypomotility, Suicide Attempt, Bradycardia, Somnolence

Suspect drug(s):
Carvedilol
    Dosage: 1125 mg (12,5 mg,90 in 1 once), oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Glimepiride
    Dosage: 180 mg (2 mg,90 in 1 once), oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Lorazepam
    Dosage: 50 mg (1 mg,50 in 1 , oral
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Novodigal 0,2 (0,2 MG) (Digoxin)
    Dosage: 20 mg (0,2 mg,100 in 1 once), oral
    Indication: Drug USE FOR Unknown Indication

Adverse event in 41 year old male receiving Lorazepam

Reported by a individual with unspecified qualification from United States on 2007-06-27

Patient: 41 year old male, weighing 68.4 kg (150.5 pounds)

Adverse reactions / side effects: Confusional State, Faecal Incontinence, Fall, Oxygen Saturation Decreased

Suspect drug(s):
Lorazepam
    Dosage: 0.5 mg po hs prn
    Administration route: Oral
    Indication: Anxiety
    Start date: 2006-10-17

Lorazepam
    Dosage: 0.5 mg po hs prn
    Administration route: Oral
    Indication: Anxiety
    Start date: 2006-10-23

Oxycodone HCL
    Dosage: 5-10 mg q 4h prn
    Indication: Pain
    Start date: 2006-10-17

Oxycodone HCL
    Dosage: 5-10 mg q 4h prn
    Indication: Pain
    Start date: 2006-10-18

Oxycodone HCL
    Dosage: 5-10 mg q 4h prn
    Indication: Pain
    Start date: 2006-10-23

Zolpidem Tartrate
    Dosage: 10 mg po hs prn
    Administration route: Oral
    Indication: Insomnia
    Start date: 2006-10-19

Zolpidem Tartrate
    Dosage: 10 mg po hs prn
    Administration route: Oral
    Indication: Insomnia
    Start date: 2006-10-23

Other drugs received by patient: Cyclosporine; Valacyclovir; Omeprazole; Haloperidol; Potassium Chloride; Sucralfate; Budesonide; Hydrocortisone; Levofloxacin; Voriconazole; Zosyn; Zolpidem Tartrate; Lorazepam; Oxycodone HCL