Gemzar (Gemcitabine) - Adverse Event Reports - Other Serious Reactions - Malignant Neoplasm Progression

Adverse event in female receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-10-18

Patient: female, weighing 53.1 kg (116.7 pounds)

Adverse reactions / side effects: Vomiting, Nausea, Malignant Neoplasm Progression, Anaemia, Hypotension, Pyrexia, Hypokalaemia, Dehydration, Intervertebral Disc Degeneration, Pathological Fracture, Leukopenia

Adverse event resulted in: hospitalization

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Procrit; Kytril; Aloxi; Zyrtec; Centrum; Ibuprin

Adverse event in 64 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-10-05

Patient: 64 year old male

Adverse reactions / side effects: Asthma, Cryptogenic Organising Pneumonia, Malignant Neoplasm Progression, Condition Aggravated, Pneumothorax

Adverse event resulted in: hospitalization

Suspect drug(s):
Gemzar
    Indication: Biliary Cancer Metastatic
    Start date: 2006-01-01

Gemzar
    Dosage: 1000mg/m2, other
    Start date: 2007-08-14

Other drugs received by patient: Tarceva; Oxaliplatin

Adverse event in female receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-10-04

Patient: female, weighing 134.2 kg (295.3 pounds)

Adverse reactions / side effects: Pneumonia, Anxiety Disorder, Dyspnoea, Diabetes Mellitus, Supraventricular Tachycardia, Hypotension, Anaemia, Malignant Neoplasm Progression, Pulmonary Embolism, Chronic Obstructive Pulmonary Disease, Cardiomegaly, Osteoarthritis, Diarrhoea, Pleural Effusion, Deep Vein Thrombosis

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Clonidine; Metoprolol; Diovan; Tylenol W / Codeine; Carbidopa and Levodopa; Hydralazine HCL; Multi-Vitamin; Prednisone; Prednisone; Voltaren / SCH /; Amaryl; Magnesium Sulfate; Vitamin B-12; Emend; Aloxi

Adverse event in 32 year old female receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-07-30

Patient: 32 year old female

Adverse reactions / side effects: Malignant Neoplasm Progression, Pleural Effusion

Adverse event resulted in: hospitalization

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Navelbine

Adverse event in male receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-07-16

Patient: male

Adverse reactions / side effects: Jaundice, Blood Alkaline Phosphatase Increased, Disseminated Intravascular Coagulation, Malignant Neoplasm Progression, Platelet Count Decreased

Suspect drug(s):
Gemzar (Gemcitabine)

Adverse event in 62 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-07-16

Patient: 62 year old male, weighing 55.3 kg (121.7 pounds)

Adverse reactions / side effects: Nausea, Cholangitis, Malignant Neoplasm Progression, Malignant Pleural Effusion

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Gemzar
    Dosage: 1600 mg, other
    Indication: Bile Duct Cancer
    Start date: 2006-07-21
    End date: 2006-09-29

Gemzar
    Dosage: 1400 mg, other
    Start date: 2006-10-06
    End date: 2007-01-05

Other drugs received by patient: UFT; Lasix

Adverse event in 62 year old female receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-06-27

Patient: 62 year old female, weighing 79.8 kg (175.6 pounds)

Adverse reactions / side effects: Blood Pressure Systolic Decreased, Night Sweats, Pulmonary Hypertension, Bacteria Urine Identified, Pneumonia, Nausea, Chills, Malignant Neoplasm Progression, Urine Output Decreased, Full Blood Count Decreased, Rash Macular, Thrombocytopenia, Cardiac Failure Congestive

Suspect drug(s):
Alimta
    Dosage: 915 mg,
    Indication: Lung Adenocarcinoma Stage IV
    Start date: 2007-05-18

Gemzar
    Indication: Lung Adenocarcinoma Stage IV
    Start date: 2006-12-11
    End date: 2007-03-05

Other drugs received by patient: Carboplatin; Folic Acid; Vitamin B12; Decadron / CAN / (Dexamethasone); Ambien; Atenolol; Duoneb; Emend; K-DUR 10; Lasix; Lexapro; Lortab; Oxygen (Oxygen)

Adverse event in 56 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from Germany on 2007-06-27

Patient: 56 year old male

Adverse reactions / side effects: Vomiting, Nausea, Malignant Neoplasm Progression, Mucosal Haemorrhage, Pancytopenia, Platelet Count Increased, Pyrexia, Renal Impairment, Renal Failure, Platelet Count Decreased

Adverse event resulted in: death, hospitalization, disablity

Suspect drug(s):
Alimta
    Dosage: 875 mg, unk
    Indication: non-Small Cell Lung Cancer
    Start date: 2006-12-12
    End date: 2007-05-09

Gemzar
    Dosage: 1000 mg/m2, unk
    Indication: non-Small Cell Lung Cancer
    Start date: 2006-04-28
    End date: 2006-10-04

Other drugs received by patient: Cisplatin; Vitamin B-12; Folsaeure; Dexamethasone; Zometa

Adverse event in 68 year old female receiving Gemzar (Gemcitabine)

Reported by a consumer/non-health professional from United States on 2007-06-25

Patient: 68 year old female

Adverse reactions / side effects: Malignant Neoplasm Progression

Suspect drug(s):
Gemzar (Gemcitabine)

Adverse event in 56 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from Germany on 2007-06-21

Patient: 56 year old male

Adverse reactions / side effects: Vomiting, Nausea, Malignant Neoplasm Progression, Mucosal Haemorrhage, Pancytopenia, Pyrexia, Renal Failure, Renal Impairment

Adverse event resulted in: death, hospitalization, disablity

Suspect drug(s):
Alimta
    Dosage: unk, unk
    Indication: non-Small Cell Lung Cancer
    Start date: 2006-12-12
    End date: 2007-05-09

Gemzar
    Dosage: unk, unk
    Indication: non-Small Cell Lung Cancer
    Start date: 2006-04-28
    End date: 2006-10-04

Other drugs received by patient: Cisplatin

Adverse event in 66 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-05-30

Patient: 66 year old male

Adverse reactions / side effects: Gastric Perforation, Malignant Neoplasm Progression, Gastric Ulcer

Adverse event resulted in: death

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Fluorouracil; Therapeutic Radiopharmaceuticals

Adverse event in 74 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-05-22

Patient: 74 year old male, weighing 55.0 kg (121.0 pounds)

Adverse reactions / side effects: White Blood Cell Count Decreased, Pneumonia, Respiratory Failure, Interstitial Lung Disease, Malignant Neoplasm Progression, Platelet Count Decreased, Pyrexia, Metastases TO Central Nervous System, Pulmonary Fibrosis

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Navalbine; Meilax; Predonine; Predonine; Solanax; Gaster D / JPN /; Loxonin; Selbex; Aspirin

Adverse event in 68 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-05-08

Patient: 68 year old male, weighing 47.1 kg (103.6 pounds)

Adverse reactions / side effects: Haemoglobin Decreased, Nephritis Interstitial, Gastrointestinal Haemorrhage, Malignant Neoplasm Progression, Renal Failure Acute, Ascites

Adverse event resulted in: death

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Gaster; Loxonin; Selbex; Lasix

Adverse event in 42 year old female receiving Gemzar (Gemcitabine)

Reported by a consumer/non-health professional from United States on 2007-04-27

Patient: 42 year old female

Adverse reactions / side effects: Thrombosis, Malignant Neoplasm Progression

Adverse event resulted in: death

Suspect drug(s):
Gemzar (Gemcitabine)

Adverse event in 74 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-04-26

Patient: 74 year old male, weighing 55.0 kg (121.0 pounds)

Adverse reactions / side effects: White Blood Cell Count Decreased, Pneumonia, Interstitial Lung Disease, Respiratory Failure, Malignant Neoplasm Progression, Platelet Count Decreased, Pyrexia, Metastases TO Central Nervous System

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Navalbine; Meilax; Predonine; Predonine; Solanax; Gaster D / JPN /; Loxonin; Selbex; Aspirin

Adverse event in 58 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from France on 2007-04-20

Patient: 58 year old male, weighing 108.0 kg (237.6 pounds)

Adverse reactions / side effects: Renal Failure, Malignant Neoplasm Progression, Thrombocytopenia, Microangiopathy, Hypertension

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Cisplatin; Carboplatin; Atenolol; Triatec; Insulin

Adverse event in 51 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-04-04

Patient: 51 year old male

Adverse reactions / side effects: Conjunctivitis, Malignant Neoplasm Progression, Injection Site Irritation

Suspect drug(s):
Alimta
    Dosage: intravenous
    Indication: non-Small Cell Lung Cancer

Gemzar
    Dosage: intravenous
    Indication: non-Small Cell Lung Cancer
    Start date: 2006-12-01

Adverse event in 71 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-03-23

Patient: 71 year old male

Adverse reactions / side effects: Weight Decreased, Abdominal Pain, Malignant Neoplasm Progression, Pulmonary Embolism, Caecitis, Fatigue, Dyspnoea Exertional, Cardio-Respiratory Arrest, Thrombocytopenia, Decreased Appetite, Cough, Renal Failure Acute, Phlebitis, Nausea, Anaemia, Pancytopenia, Neutrophilia, Musculoskeletal Chest Pain, Cardiogenic Shock, Cholelithiasis, Limb Discomfort, Ageusia, Alopecia, Asthenia, Leukopenia, Deep Vein Thrombosis, Neuralgia

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Alimta
    Dosage: 750 mg, unk
    Indication: non-Small Cell Lung Cancer
    Start date: 2006-12-22

Gemzar
    Dosage: 1900 mg, unk
    Start date: 2006-08-16
    End date: 2006-12-01

Gemzar
    Dosage: 1450 mg, unk
    Start date: 2006-11-17
    End date: 2006-11-17

Other drugs received by patient: Carboplatin; Carboplatin; Carboplatin; Carboplatin; Prevacid; Welchol; Tylenol W / Codeine NO. 2; Decadron / CAN /; Aloxi; Compazine; Avelox; Neulasta; Vitamin B-12; Folic Acid

Adverse event in 63 year old male receiving Gemzar (Gemcitabine)

Reported by a consumer/non-health professional from United States on 2007-03-13

Patient: 63 year old male, weighing 84.4 kg (185.6 pounds)

Adverse reactions / side effects: Malignant Neoplasm Progression, Pain, Arteriosclerosis Coronary Artery, Splenomegaly, Cardiomegaly, Bladder Cancer, Hydrocele

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Cisplatin; Taxotere; Carboplatin; Vitamins NOS; Aspirin; Niacin; Xanax; Marijuana

Adverse event in 73 year old female receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-03-09

Patient: 73 year old female

Adverse reactions / side effects: Carcinoembryonic Antigen Increased, Disseminated Intravascular Coagulation, Malignant Neoplasm Progression, Jaundice Cholestatic

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Gemzar
    Dosage: 1000 mg/m2, other
    Indication: Pancreatic Carcinoma
    Start date: 2005-01-01

Gemzar
    Dosage: 1000 mg/m2, weekly (1/w)

Other drugs received by patient: Fluorouracil; Fluorouracil

Adverse event in 51 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-03-09

Patient: 51 year old male

Adverse reactions / side effects: Conjunctivitis, Malignant Neoplasm Progression, Injection Site Irritation

Suspect drug(s):
Alimta
    Dosage: intravenous
    Indication: non-Small Cell Lung Cancer

Gemzar
    Dosage: intravenous
    Indication: non-Small Cell Lung Cancer
    Start date: 2006-12-01

Adverse event in 60 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-02-20

Patient: 60 year old male

Adverse reactions / side effects: Vasculitis Necrotising, Sepsis, Malignant Neoplasm Progression, Scleroderma, Thrombocytopenia

Adverse event resulted in: death

Suspect drug(s):
Gemzar
    Dosage: 2000 mg, other
    Indication: Bladder Cancer Stage IV
    Start date: 2005-10-01
    End date: 2005-01-01

Gemzar
    Dosage: 1500 mg, other
    Start date: 2005-01-01
    End date: 2005-01-01

Gemzar
    Dosage: 1000 mg, other
    Start date: 2005-01-01
    End date: 2005-12-01

Other drugs received by patient: Cisplatin

Adverse event in 60 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from United States on 2007-02-20

Patient: 60 year old male

Adverse reactions / side effects: Vasculitis Necrotising, Sepsis, Malignant Neoplasm Progression, Scleroderma, Thrombocytopenia

Adverse event resulted in: death

Suspect drug(s):
Gemzar
    Dosage: 2000 mg, other
    Indication: Bladder Cancer Stage IV
    Start date: 2005-10-01

Gemzar
    Dosage: 1500 mg/m2, other
    Start date: 2005-01-01
    End date: 2005-01-01

Gemzar
    Dosage: 1000 mg/m2, other
    Start date: 2005-01-01
    End date: 2005-12-01

Other drugs received by patient: Cisplatin; Taxol; Carboplatin

Adverse event in 71 year old male receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-02-16

Patient: 71 year old male, weighing 63.0 kg (138.6 pounds)

Adverse reactions / side effects: Weight Decreased, Nausea, Pain, Disseminated Intravascular Coagulation, Malignant Neoplasm Progression, Malaise, Interstitial Lung Disease, Bile Duct Stenosis, Anorexia, Bone Marrow Failure, Oedema, Pancreatitis

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Gemzar
    Dosage: 1000 mg, other
    Indication: Pancreatic Carcinoma
    Start date: 2006-06-07
    End date: 2006-06-07

Gemzar
    Dosage: 600 mg, other
    Start date: 2006-07-05
    End date: 2006-08-30

Gemzar
    Dosage: 200 mg, other
    Start date: 2006-09-06
    End date: 2006-10-04

Other drugs received by patient: Omepral; Camostat Mesilate; Furosemide; Pentagin; Pentagin; Magmitt; Sigmart; Cyanocobalamin; Diltiazem HCL; Pentagin; Kentan; Sennoside; Prednisolone; Prednisolone; Nafamostat Mesilate; Pioglitazone HCL; Nasea; Nafamostat Mesilate; Corticosteroids; Corticosteroids

Adverse event in male receiving Gemzar (Gemcitabine)

Reported by a physician from Japan on 2007-02-13

Patient: male

Adverse reactions / side effects: Disseminated Intravascular Coagulation, Malignant Neoplasm Progression, Platelet Count Decreased, Liver Disorder

Adverse event resulted in: death

Suspect drug(s):
Gemzar (Gemcitabine)

Other drugs received by patient: Irinotecan HCL