Elavil (Amitriptyline) - Adverse Event Reports - Death

Confusional State (2),  Drug Ineffective (2),  Multiple Drug Overdose Accidental (2),  Completed Suicide (2),  Respiratory Arrest (2),  Pain in Extremity (1),  Sensory Loss (1),  DRY Skin (1),  Depression (1),  Asthenia (1)

Adverse event in 74 year old female receiving Elavil (Amitriptyline)

Reported by a pharmacist from Canada on 2007-06-05

Patient: 74 year old female, weighing 86.0 kg (189.2 pounds)

Adverse reactions / side effects: Confusional State, Death, Tachycardia, Hyperthermia Malignant, DRY Skin, Lung Infiltration, Muscle Rigidity

Adverse event resulted in: death

Suspect drug(s):
Paxil
    Dosage: 10mg per day
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Fentanyl
    Dosage: 25mg per day

Elavil
    Dosage: 25mg as required

Other drugs received by patient: Avandia; Novasen; Ferrous Sulfate; Adalat; Prevacid; Flovent; Novolin 50 / 50; Pulmicort; Quinine Sulfate

Adverse event in female receiving Elavil (Amitriptyline)

Reported by a physician from United States on 2007-04-03

Patient: female, weighing 60.8 kg (133.7 pounds)

Adverse reactions / side effects: Confusional State, Medication Error, Completed Suicide, Respiratory Arrest, Drug Interaction, Narcotic Intoxication

Adverse event resulted in: death

Suspect drug(s):
Duragesic-100
    Indication: Pain

Elavil
    Indication: Depression

Nexium
    Indication: Gastrooesophageal Reflux Disease

Other drugs received by patient possibly interacting with the suspect drug:
Carisoprodol
    Indication: Muscle Relaxant Therapy

Adverse event in male receiving Elavil (Amitriptyline)

Reported by a lawyer from United States on 2007-03-08

Patient: male

Adverse reactions / side effects: Multiple Drug Overdose Accidental, Drug Ineffective, Completed Suicide, Prescribed Overdose, Cardiac Arrest

Adverse event resulted in: death

Suspect drug(s):
Neurontin
    Indication: Necrosis

Neurontin
    Indication: Pain

Oxycontin

Hydrocodone

Endocet

Elavil

Adverse event in 42 year old female receiving Elavil (Amitriptyline)

Reported by a individual with unspecified qualification from United States on 2007-01-26

Patient: 42 year old female, weighing 92.0 kg (202.4 pounds)

Adverse reactions / side effects: Drug Ineffective, Pain in Extremity, Pain, Sensory Loss, Drug Withdrawal Syndrome, Headache, Suicidal Ideation, Anxiety, Overdose, Multiple Drug Overdose Accidental, Areflexia, Mental Disorder, Depression, Drug Dependence, Asthenia

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Oxycontin
    Dosage: 10 mg, bid
    Indication: Drug USE FOR Unknown Indication
    Start date: 2001-05-01
    End date: 2002-06-26

Oxycontin
    Dosage: 20 mg, tid

Ethanol
    Dosage: unk unk, unk
    Indication: Alcohol USE

Elavil
    Dosage: unk unk, unk
    Indication: Drug USE FOR Unknown Indication

Nortriptyline HCL
    Dosage: unk unk, unk
    Indication: Drug USE FOR Unknown Indication

Paxil
    Dosage: unk unk, unk
    Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Neomycin; Tegretol; Neurontin; Aciphex; Estratest; Bellergal-S; Propoxyphene Hydrochloride; Atenolol; Imitrex ^cerenex^; Lorazepam; Reglan; Trimethobenzamide; Hydroxyzine; Tenormin; Premarin; Prilosec; Zonegran; Topamax; Lamictal; Vitamins

Adverse event in 27 year old male receiving Elavil (Amitriptyline)

Reported by a health professional (non-physician/pharmacist) from United States on 2007-01-12

Patient: 27 year old male

Adverse reactions / side effects: Respiratory Arrest, Accidental Overdose

Adverse event resulted in: death, life threatening event, hospitalization

Suspect drug(s):
Elavil
    Dosage: dose unknown at bedtime oral (duration: one dose )
    Administration route: Oral
    Start date: 2004-11-01

Methadone
    Dosage: ? dose - total of 3 tablets a day oral
    Administration route: Oral
    Indication: Arthralgia
    Start date: 2004-11-01
    End date: 2005-01-23

Other drugs received by patient: Lexapro