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Index of reports
> Cases resulting in life threatening events (51)
> Cases with Blood Lactate Dehydrogenase Increased (18)
Below is the selection of adverse event reports related to Diovan (Valsartan) that includes cases resulting in life threatening events where reactions include blood lactate dehydrogenase increased.
Adverse event in 35 year old male receiving Diovan (Valsartan)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-30
Patient: 35 year old male
Adverse reactions / side effects: Blood Alkaline Phosphatase Decreased, Vomiting, Blood Lactate Dehydrogenase Increased, Paralysis, Overdose, Fibrin Increased, Shock, White Blood Cell Count Increased
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Adalat
Dosage: oral
Administration route: Oral
Start date: 2007-08-18
End date: 2007-08-18
Allopurinol
Dosage: oral
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Carvedilol
Dosage: oral
Administration route: Oral
Start date: 2007-08-18
End date: 2007-08-18
Diovan
Dosage: oral
Administration route: Oral
Start date: 2007-08-18
End date: 2007-08-18
Olmesartan Medoxomil
Dosage: oral
Administration route: Oral
Start date: 2007-08-18
End date: 2007-08-18
Adverse event in 35 year old male receiving Diovan (Valsartan)
Reported by a individual with unspecified qualification from United Kingdom on 2007-10-19
Patient: 35 year old male
Adverse reactions / side effects: Blood Alkaline Phosphatase Decreased, Vomiting, Hypotension, Blood Lactate Dehydrogenase Increased, Paralysis, Gastrointestinal Tube Insertion, Respiratory Rate Decreased, Overdose, Heart Rate Decreased, White Blood Cell Count Increased, Shock, Fibrin Increased
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Adalat
Dosage: 40 mg x 40 tablets
Administration route: Oral
Start date: 2007-08-18
End date: 2007-08-18
Allopurinol
Dosage: 100 mg x 32 tablets
Administration route: Oral
Start date: 2007-08-18
End date: 2007-08-18
Carvedilol
Dosage: 10 mg x 32 tablets
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Diovan
Dosage: 40mgx 8 tablets
Administration route: Oral
Start date: 2007-08-18
End date: 2007-08-18
Olmetec
Dosage: 20 mg x 74 tablets
Administration route: Oral
Start date: 2007-08-18
End date: 2007-08-18
Other drugs received by patient: Alcohol
Adverse event in 35 year old male receiving Diovan (Valsartan)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-09
Patient: 35 year old male
Adverse reactions / side effects: Blood Alkaline Phosphatase Decreased, Vomiting, Blood Lactate Dehydrogenase Increased, Paralysis, Overdose, Fibrin Increased, Shock, White Blood Cell Count Increased
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Adalat
Dosage: 1920mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Allopurinol
Dosage: 32000mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Artist
Dosage: 320mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Diovan
Dosage: 320mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Olmetec
Dosage: 1480mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Adverse event in 35 year old male receiving Diovan (Valsartan)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-09
Patient: 35 year old male
Adverse reactions / side effects: Blood Alkaline Phosphatase Decreased, Vomiting, Blood Lactate Dehydrogenase Increased, Paralysis, Overdose, Fibrin Increased, Shock, White Blood Cell Count Increased
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Adalat
Dosage: 1920mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Allopurinol
Dosage: 32000mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Artist
Dosage: 320mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Diovan
Dosage: 320mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Olmetec
Dosage: 1480mg per day
Administration route: Oral
Indication: Self Mutilation
Start date: 2007-08-18
End date: 2007-08-18
Adverse event in 78 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-07-26
Patient: 78 year old male, weighing 52.0 kg (114.4 pounds)
Adverse reactions / side effects: Jaundice, Eosinophil Count Decreased, Blood Bilirubin Increased, Nasopharyngitis, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Liver Disorder, Weight Increased, Haemoglobin Decreased, Haematocrit Decreased, Malaise, Gamma-Glutamyltransferase Increased, RED Blood Cell Count Decreased, Aspartate Aminotransferase Increased, Peritoneal Effusion
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan
Dosage: 40 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 2006-11-01
Flomox
Dosage: 300 mg/day
Administration route: Oral
Indication: Upper Respiratory Tract Inflammation
Start date: 2007-05-21
End date: 2007-05-25
Kakkon-TO
Dosage: 7.5 g/day
Administration route: Oral
Indication: Upper Respiratory Tract Inflammation
Start date: 2007-05-21
End date: 2007-05-25
Adverse event in 84 year old female receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-07-25
Patient: 84 year old female, weighing 38.0 kg (83.6 pounds)
Adverse reactions / side effects: Blood Bilirubin Increased, Blood Alkaline Phosphatase Increased, Hepatic Function Abnormal, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Purpura, Eosinophilia, Cholelithiasis, Gamma-Glutamyltransferase Increased, Aspartate Aminotransferase Increased, Platelet Count Decreased, Thrombocytopenia, Bilirubin Conjugated Increased
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan (Valsartan)
Other drugs received by patient: Spiriva; Frandol
Adverse event in 78 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-07-24
Patient: 78 year old male, weighing 52.0 kg (114.4 pounds)
Adverse reactions / side effects: Jaundice, Eosinophil Count Decreased, Blood Bilirubin Increased, Nasopharyngitis, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Liver Disorder, Weight Increased, Haemoglobin Decreased, Haematocrit Decreased, Malaise, Gamma-Glutamyltransferase Increased, RED Blood Cell Count Decreased, Aspartate Aminotransferase Increased, Peritoneal Effusion
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan
Dosage: 40 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 2006-11-01
Flomox
Dosage: 300 mg/day
Administration route: Oral
Indication: Upper Respiratory Tract Inflammation
Start date: 2007-05-21
End date: 2007-05-25
Kakkon-TO
Dosage: 7.5 g/day
Administration route: Oral
Indication: Upper Respiratory Tract Inflammation
Start date: 2007-05-21
End date: 2007-05-25
Adverse event in 87 year old female receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-07-23
Patient: 87 year old female, weighing 35.0 kg (77.0 pounds)
Adverse reactions / side effects: Blood Bilirubin Increased, Coagulopathy, Cholestasis, Coma, Hepatic Failure, Gastrointestinal Tube Insertion, Liver Disorder, Hepatic Encephalopathy, Subdural Haematoma, Malaise, Gamma-Glutamyltransferase Increased, Cholecystitis, Gallbladder Disorder, Prothrombin Time Ratio Increased, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Tremor, Cholelithiasis, Anorexia, Aspartate Aminotransferase Increased, Gallbladder Polyp
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Amaryl
Dosage: 1 mg/day
Administration route: Oral
Indication: Diabetes Mellitus
Start date: 2007-04-01
End date: 2007-05-17
Aspirin
Dosage: 100 mg/day
Administration route: Oral
Indication: Angina Pectoris
Start date: 2007-04-01
End date: 2007-05-26
Diovan
Dosage: 40 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 2006-06-14
End date: 2007-05-23
Norvasc
Dosage: 2.5 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 1999-05-01
End date: 2007-05-25
Other drugs received by patient: Roxatidine Acetate HCL; Nateglinide; Triazolam; Lisinopril; Lisinopril
Adverse event in 79 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-07-09
Patient: 79 year old male
Adverse reactions / side effects: Blood Bilirubin Increased, Pyrexia, Liver Disorder, Malaise, Haematocrit Decreased, RED Blood Cell Count Decreased, Gamma-Glutamyltransferase Increased, White Blood Cell Count Increased, Blood Glucose Increased, Lymphocyte Count Decreased, Blood Alkaline Phosphatase Increased, Blood Urea Increased, Pneumonia, Blood Lactate Dehydrogenase Increased, Alanine Aminotransferase Increased, Urine Output Decreased, Haemoglobin Decreased, Aspartate Aminotransferase Increased, Platelet Count Decreased
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan (Valsartan)
Other drugs received by patient: Lendormin; Pariet; Norvasc; Rinderon; Aspirin; Clarithromycin; Rizaben
Adverse event in 51 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-06-27
Patient: 51 year old male
Adverse reactions / side effects: Drug Eruption, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Toxic Epidermal Necrolysis, Cerebral Haemorrhage, Hypoalbuminaemia, Stevens-Johnson Syndrome, Infection
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan
Dosage: 1 dosage forms, 1 in 1 d, oral
Administration route: Oral
Indication: Hypertension
Start date: 2006-12-31
End date: 2007-03-17
Zonisamide
Dosage: 200 mg, 2 in 1 d, oral
Administration route: Oral
Indication: Cerebral Haemorrhage
Start date: 2007-01-04
End date: 2007-02-07
Other drugs received by patient: Takepron (Lansoprazole) (Lansoprazole); NI (Magnesium Oxide) (Magnesium Oxide); Pursennid (Sennoside) (Senna Leaf)
Adverse event in 51 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-06-19
Patient: 51 year old male
Adverse reactions / side effects: Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Toxic Epidermal Necrolysis, Varicella, Mycoplasma Infection, Staphylococcal Infection, NO Therapeutic Response, Hypoalbuminaemia, Dermatitis Exfoliative, White Blood Cell Count Increased, Infection
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan
Dosage: 1 dosage forms, 1 in 1 d, oral
Administration route: Oral
Indication: Hypertension
Start date: 2006-12-31
End date: 2007-03-17
Zonisamide
Dosage: 200 mg, 2 in 1 d, oral
Administration route: Oral
Indication: Cerebral Haemorrhage
Start date: 2007-01-04
End date: 2007-02-07
Other drugs received by patient: Lansoprazole; NI (Magnesium Oxide); Pursennid (Sennoside) (Senna Leaf)
Adverse event in 51 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-05-29
Patient: 51 year old male
Adverse reactions / side effects: Drug Eruption, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, NO Therapeutic Response, Toxic Epidermal Necrolysis
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan
Dosage: 1 in 1 d; oral
Administration route: Oral
Indication: Hypertension
Start date: 2006-12-31
End date: 2007-03-17
Diovan
Dosage: 1 in 1 d; oral
Administration route: Oral
Indication: Hypertension
Start date: 2006-12-31
End date: 2007-03-17
Zonisamide
Dosage: 200 mg, 2 in 1 d; oral
Administration route: Oral
Indication: Cerebral Haemorrhage
Start date: 2007-01-04
End date: 2007-02-07
Zonisamide
Dosage: 200 mg, 2 in 1 d; oral
Administration route: Oral
Indication: Cerebral Haemorrhage
Start date: 2007-01-04
End date: 2007-02-07
Other drugs received by patient: Takepron (Lansoprazole) (Lansoprazole); NI (Magnesium Oxide ) (Magnesium Oxide); Pursennid (Sennoside) (Senna Leaf); Takepron (Lansoprazole) (Lansoprazole); NI (Magnesium Oxide ) (Magnesium Oxide); Pursennid (Sennoside) (Senna Leaf)
Adverse event in 51 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-05-22
Patient: 51 year old male
Adverse reactions / side effects: Drug Eruption, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Toxic Epidermal Necrolysis, Pyrexia, Dermatitis Exfoliative, Stevens-Johnson Syndrome
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan
Dosage: 1 in 1 d, oral
Administration route: Oral
Indication: Hypertension
Start date: 2006-12-31
End date: 2007-03-17
Zonisamide
Dosage: 200 mg, 2 in 1 d, oral
Administration route: Oral
Indication: Cerebral Haemorrhage
Start date: 2007-01-04
End date: 2007-02-07
Other drugs received by patient: Takepron (Lansoprazole) (Lansoprazole); NI (Magnesium Oxide) (Magnesium Oxide); Pursennid (Sennoside) (Senna Leaf)
Adverse event in 51 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-05-14
Patient: 51 year old male
Adverse reactions / side effects: Drug Eruption, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Toxic Epidermal Necrolysis, Pyrexia, White Blood Cell Count Increased
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Diovan
Dosage: 1 in 1 d, oral
Administration route: Oral
Indication: Hypertension
Start date: 2006-12-31
End date: 2007-03-17
Zonisamide
Dosage: 200 mg, 2 in 1 d, oral
Administration route: Oral
Indication: Cerebral Haemorrhage
Start date: 2007-01-04
End date: 2007-02-07
Other drugs received by patient: Lansoprazole; (Magnesium Oxide) (Magnesium Oxide); Pursennid (Sennoside) (Senna Leaf)
Adverse event in 76 year old male receiving Diovan (Valsartan)
Reported by a pharmacist from Japan on 2007-03-05
Patient: 76 year old male
Adverse reactions / side effects: Choking Sensation, PO2 Decreased, Interstitial Lung Disease, C-Reactive Protein Increased, Palpitations, Tracheostomy, Blood Bicarbonate Increased, Cell Marker Increased, Acute Respiratory Failure, White Blood Cell Count Increased, Oxygen Saturation Decreased, Blood Alkaline Phosphatase Increased, Dyspnoea, Blood Lactate Dehydrogenase Increased, Lung Disorder, Hypertension, Inflammation
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Diovan (Valsartan)
Other drugs received by patient: Adalat; Actos; Lasix
Adverse event in 76 year old male receiving Diovan (Valsartan)
Reported by a pharmacist from Japan on 2007-02-27
Patient: 76 year old male
Adverse reactions / side effects: Choking Sensation, PO2 Decreased, Interstitial Lung Disease, C-Reactive Protein Increased, Palpitations, Tracheostomy, Blood Bicarbonate Increased, Cell Marker Increased, Acute Respiratory Failure, White Blood Cell Count Increased, Oxygen Saturation Decreased, Blood Alkaline Phosphatase Increased, Dyspnoea, Blood Lactate Dehydrogenase Increased, Lung Disorder, Hypertension, Inflammation
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Diovan (Valsartan)
Other drugs received by patient: Adalat; Actos; Lasix
Adverse event in 76 year old male receiving Diovan (Valsartan)
Reported by a pharmacist from Japan on 2007-02-19
Patient: 76 year old male
Adverse reactions / side effects: Choking Sensation, PO2 Decreased, Interstitial Lung Disease, C-Reactive Protein Increased, Palpitations, Tracheostomy, Blood Bicarbonate Increased, Acute Respiratory Failure, Cell Marker Increased, Oxygen Saturation Decreased, White Blood Cell Count Increased, Blood Alkaline Phosphatase Increased, Dyspnoea, Blood Lactate Dehydrogenase Increased, Lung Disorder, Hypertension, Inflammation
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Actos
Dosage: 15 mg/day
Administration route: Oral
Indication: Diabetes Mellitus
Start date: 2005-08-29
End date: 2006-10-16
Adalat
Dosage: 40 mg/ day
Administration route: Oral
Indication: Hypertension
Start date: 2005-08-29
End date: 2006-10-16
Diovan
Dosage: 80 mg, tid
Administration route: Oral
Indication: Hypertension
Start date: 2005-08-25
End date: 2006-10-16
Lasix
Dosage: 20 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 2005-08-29
End date: 2006-10-16
Adverse event in 76 year old male receiving Diovan (Valsartan)
Reported by a physician from Japan on 2007-02-12
Patient: 76 year old male
Adverse reactions / side effects: Choking Sensation, PO2 Decreased, Palpitations, Interstitial Lung Disease, Tracheostomy, Blood Bicarbonate Increased, Cell Marker Increased, Acute Respiratory Failure, White Blood Cell Count Increased, Oxygen Saturation Decreased, Blood Alkaline Phosphatase Increased, Dyspnoea, Blood Lactate Dehydrogenase Increased, Lung Disorder, Hypertension, Inflammation
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Diovan (Valsartan)
Other drugs received by patient: Adalat; Actos; Lasix
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