Diovan HCT (Valsartan / Hydrochlorothiazide) - Adverse Event Reports - Life Threatening Events

Hypotension (3),  Renal Failure (2),  Fatigue (2),  Blood Creatinine Increased (2),  Arterial Disorder (1),  Stent Placement (1),  Pulmonary Embolism (1),  Sepsis (1),  Asthenia (1),  Renal Failure Acute (1)

Adverse event in 59 year old female receiving Diovan HCT (Valsartan / Hydrochlorothiazide)

Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-15

Patient: 59 year old female, weighing 71.2 kg (156.6 pounds)

Adverse reactions / side effects: Blood Urea Increased, Pulmonary Artery Aneurysm, Liver Function Test Abnormal, Proteinuria, Sepsis, Blood Creatinine Increased, Renal Failure Acute, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Diovan HCT
    Administration route: Oral
    Indication: Hypertension

Ibuprofen
    Dosage: 600 mg, tid
    Administration route: Oral
    Indication: Headache
    End date: 2007-03-27

Other drugs received by patient: Crestor; Amitriptyline HCL; Fish OIL; Calcium with Vitamin D; Vitamin CAP

Adverse event in female receiving Diovan HCT (Valsartan / Hydrochlorothiazide)

Reported by a individual with unspecified qualification from United States on 2007-10-09

Patient: female

Adverse reactions / side effects: Embolism, Hypotension, Pulmonary Embolism, Oxygen Saturation Decreased

Adverse event resulted in: life threatening event

Suspect drug(s):
Diovan HCT
    Dosage: 80 mg val 12.5 hct, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2006-12-08
    End date: 2007-09-11

Premarin
    Dosage: unk, unk

Adverse event in 67 year old female receiving Diovan HCT (Valsartan / Hydrochlorothiazide)

Reported by a physician from United States on 2007-10-05

Patient: 67 year old female, weighing 52.2 kg (114.8 pounds)

Adverse reactions / side effects: Hypotension

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Diovan HCT
    Dosage: 160/25 qd, oral
    Administration route: Oral
    Indication: Hypertension

Tekturna
    Dosage: 150 mg, qd, oral
    Administration route: Oral
    Indication: Hypertension
    Start date: 2007-06-14
    End date: 2007-06-27

Other drugs received by patient: Chantix; Aciphex; Crestor

Adverse event in 69 year old male receiving Diovan HCT (Valsartan / Hydrochlorothiazide)

Reported by a individual with unspecified qualification from United States on 2007-07-19

Patient: 69 year old male, weighing 88.4 kg (194.6 pounds)

Adverse reactions / side effects: Surgery, Renal Failure, Fatigue, Neoplasm Malignant, Pollakiuria, Renal Cell Carcinoma Stage Unspecified, Gait Disturbance, Hypertension, Lung Infiltration, Blood Creatinine Increased, Decreased Appetite, Metastases TO Lung

Adverse event resulted in: life threatening event, hospitalization, disablity

Suspect drug(s):
Diovan HCT (Valsartan / Hydrochlorothiazide)

Other drugs received by patient: Indocin

Adverse event in female receiving Diovan HCT (Valsartan / Hydrochlorothiazide)

Reported by a consumer/non-health professional from United States on 2007-05-01

Patient: female, weighing 72.6 kg (159.7 pounds)

Adverse reactions / side effects: Food Aversion, Thinking Abnormal, Fear, Insomnia

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Diovan HCT (Valsartan / Hydrochlorothiazide)

Adverse event in 40 year old female receiving Diovan HCT (Valsartan / Hydrochlorothiazide)

Reported by a consumer/non-health professional from Venezuela on 2007-03-15

Patient: 40 year old female

Adverse reactions / side effects: Fatigue, Renal Failure, Respiratory Disorder, Arterial Disorder, Hypotension, Abdominal Distension, Asthenia, Cardiac Disorder, Hypertensive Crisis

Adverse event resulted in: death, life threatening event, hospitalization

Suspect drug(s):
Diovan HCT
    Dosage: 160/25 mg
    Indication: Hypertension
    End date: 2006-10-01

Foradil

Adverse event in 73 year old male receiving Diovan HCT (Valsartan / Hydrochlorothiazide)

Reported by a health professional (non-physician/pharmacist) from United States on 2007-01-23

Patient: 73 year old male

Adverse reactions / side effects: Jaundice, Stent Placement, Hepatic Enzyme Increased

Adverse event resulted in: life threatening event

Suspect drug(s):
Crestor
    Administration route: Oral
    End date: 2007-01-18

Diovan HCT
    Dosage: 12.5/160

Imdur

Temazepam

Vistaril

Zestril
    Administration route: Oral
    End date: 2007-01-18

Other drugs received by patient: Acetaminophen; Codeine Phos.; Aspirin; Coreg; Furosemide; Humulin N; Humulin 70 / 30; Klor-CON; Plavix