|
This is an index of adverse event reports related to Comtan (Entacapone). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the adverse reaction. Or scroll down to view a sample of recent reports further on this page.
Our database includes reports from Jan 2007 to Dec 2007. The information is not vetted and should not be cosidered as verified clinical evidence.
All cases (98)
Cases resulting in a serious event (95)
Cases resulting in death (25)
Cases resulting in life threatening events (5)
Cases resulting in hospitalization (36)
Cases resulting in other serious reactions (45)
Below is a sample of adverse event reports reports related to Comtan (Entacapone). For a complete list and/or a specific selection of reports, please use the links in the index above.
Adverse event in 70 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Italy on 2007-10-31
Patient: 70 year old male
Adverse reactions / side effects: Completed Suicide
Adverse event resulted in: death
Suspect drug(s):
Apomorphine Hydrochloride
Dosage: 28.8 mg/day
Indication: Parkinson's Disease
Start date: 2007-01-23
End date: 2007-10-01
Comtan
Dosage: 1400 mg/day
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2002-04-24
End date: 2007-10-01
Madopar
Dosage: 1025 mg/day
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2001-11-13
End date: 2007-10-02
Other drugs received by patient: Lexotan
Adverse event in 70 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Italy on 2007-10-30
Patient: 70 year old male
Adverse reactions / side effects: Completed Suicide
Adverse event resulted in: death
Suspect drug(s):
Apofin
Dosage: 28.8 mg subcutaneous
Indication: Parkinson's Disease
Start date: 2007-01-23
End date: 2007-10-01
Comtan
Dosage: 1400 mg oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2002-04-24
End date: 2007-10-01
Madopar
Dosage: 1025 mg oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2001-11-13
End date: 2007-10-02
Other drugs received by patient: Lexotan
Adverse event in 62 year old female receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-30
Patient: 62 year old female
Adverse reactions / side effects: Cerebral Haemorrhage
Adverse event resulted in: death
Suspect drug(s):
Comtan
Dosage: 300 mg oral
Administration route: Oral
Indication: Drug Effect Decreased
Start date: 2007-07-06
End date: 2007-07-10
Dopacol
Dosage: 4.5 df/d oral, 5 df/d oral, 5.5 df/d oral, 6.5 df/d oral, 8 df/d oral, 7 df/d oral, 6 df/d oral
Administration route: Oral
Start date: 2002-04-05
End date: 2002-11-07
Dopacol
Dosage: 4.5 df/d oral, 5 df/d oral, 5.5 df/d oral, 6.5 df/d oral, 8 df/d oral, 7 df/d oral, 6 df/d oral
Administration route: Oral
Start date: 2002-11-08
End date: 2004-01-14
Dopacol
Dosage: 4.5 df/d oral, 5 df/d oral, 5.5 df/d oral, 6.5 df/d oral, 8 df/d oral, 7 df/d oral, 6 df/d oral
Administration route: Oral
Start date: 2004-01-15
End date: 2004-10-21
Dopacol
Dosage: 4.5 df/d oral, 5 df/d oral, 5.5 df/d oral, 6.5 df/d oral, 8 df/d oral, 7 df/d oral, 6 df/d oral
Administration route: Oral
Start date: 2004-10-22
End date: 2006-01-05
Dopacol
Dosage: 4.5 df/d oral, 5 df/d oral, 5.5 df/d oral, 6.5 df/d oral, 8 df/d oral, 7 df/d oral, 6 df/d oral
Administration route: Oral
Start date: 2006-01-06
End date: 2007-04-19
Dopacol
Dosage: 4.5 df/d oral, 5 df/d oral, 5.5 df/d oral, 6.5 df/d oral, 8 df/d oral, 7 df/d oral, 6 df/d oral
Administration route: Oral
Start date: 2007-04-20
End date: 2007-07-05
Dopacol
Dosage: 4.5 df/d oral, 5 df/d oral, 5.5 df/d oral, 6.5 df/d oral, 8 df/d oral, 7 df/d oral, 6 df/d oral
Administration route: Oral
Start date: 2007-07-06
Other drugs received by patient: Ferromia
Adverse event in 72 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-29
Patient: 72 year old male
Adverse reactions / side effects: Pneumonia Aspiration, General Physical Health Deterioration, Somnolence
Adverse event resulted in: hospitalization
Suspect drug(s):
Comtan (Entacapone)
Other drugs received by patient: NEO Dopaston; Cabergoline; Warfarin Sodium
Adverse event in 71 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-29
Patient: 71 year old male
Adverse reactions / side effects: Blood Pressure Systolic Increased, Tachycardia, Blood Pressure Fluctuation
Suspect drug(s):
Comtan (Entacapone)
Adverse event in 62 year old female receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-29
Patient: 62 year old female
Adverse reactions / side effects: Cardio-Respiratory Arrest, Excoriation, Sudden Death, Cardiogenic Shock, Chest Injury, Fall, Haemolysis, Organ Failure
Adverse event resulted in: death
Suspect drug(s):
Alfarol
Dosage: 0.5 mg oral
Administration route: Oral
Clonazepam
Dosage: 1 mg oral
Administration route: Oral
Indication: Hypoaesthesia
Comtan
Dosage: 300 mg (100 mg, 3 in 1 d) oral
Administration route: Oral
Indication: Drug Effect Decreased
Start date: 2007-08-09
Comtan
Dosage: 300 mg (100 mg, 3 in 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-08-09
Depas
Dosage: 0.5 mg oral
Administration route: Oral
Indication: Insomnia
End date: 2007-09-01
Dops
Dosage: 300 mg oral
Administration route: Oral
Indication: Hypotension
Start date: 1993-02-24
LAC B
Dosage: 3 g oral
Administration route: Oral
Indication: Constipation
Start date: 2003-07-15
Maglax
Dosage: 990 mg oral
Administration route: Oral
Indication: Constipation
Neodopasol
Dosage: 300 mg oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 1993-06-03
Pantosin
Dosage: 300 mg oral
Administration route: Oral
Indication: Constipation
Pramipexole Dihydrochloride
Dosage: 1.5 mg oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2005-07-07
Adverse event in 57 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-25
Patient: 57 year old male
Adverse reactions / side effects: Incoherent, Delusional Disorder, Unspecified Type, Legal Problem, Psychiatric Symptom, Abnormal Behaviour, Amnesia, Constipation
Adverse event resulted in: hospitalization
Suspect drug(s):
Artane
Dosage: 6 mg (2 mg, 3 in 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Comtan
Dosage: 300 mg (100 mg, 3 in 1 d) oral
Administration route: Oral
Indication: Drug Effect Decreased
Start date: 2007-07-19
FP
Dosage: 7.5 mg (2.5 mg, 3 in 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-06-14
Menesit
Dosage: 500 mg (100 mg, 5 in 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Requip
Dosage: 6 mg (2 mg, 3 in 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Rivotril
Dosage: 6 mg (2 mg, 3 in 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Other drugs received by patient: Ternelin; Milmag
Adverse event in male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from United States on 2007-10-25
Patient: male
Adverse reactions / side effects: Drug Ineffective, Paralysis, Pharmaceutical Product Complaint
Suspect drug(s):
Comtan (Entacapone)
Adverse event in 75 year old female receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-25
Patient: 75 year old female
Adverse reactions / side effects: Treatment Noncompliance, Hallucination
Suspect drug(s):
Comtan
Dosage: 300 mg oral, 500 mg, 400 mg
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-07-09
End date: 2007-07-29
Comtan
Dosage: 300 mg oral, 500 mg, 400 mg
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-07-30
End date: 2007-09-09
Comtan
Dosage: 300 mg oral, 500 mg, 400 mg
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-09-10
End date: 2007-10-02
Other drugs received by patient: NEO Dopaston
Adverse event in 65 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-25
Patient: 65 year old male
Adverse reactions / side effects: Anxiety, Rhabdomyolysis, Heat Stroke, Dehydration, Abasia, Dyskinesia, Muscular Weakness
Adverse event resulted in: hospitalization
Suspect drug(s):
Comtan (Entacapone)
Other drugs received by patient: Symmetrel; Madopar; Aspirin; Raden; Theo Slow; FP; Biofermin
Adverse event in 70 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Italy on 2007-10-25
Patient: 70 year old male
Adverse reactions / side effects: Completed Suicide
Adverse event resulted in: death
Suspect drug(s):
Apomorphine Hydrochloride
Dosage: 28.8 mg/day
Indication: Parkinson's Disease
Start date: 2007-01-23
End date: 2007-10-01
Comtan
Dosage: 1400 mg/day
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2002-04-24
End date: 2007-10-01
Madopar
Dosage: 1025 mg/day
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2001-11-13
End date: 2007-10-02
Other drugs received by patient: Lexotan
Adverse event in 74 year old male receiving Comtan (Entacapone)
Reported by a pharmacist from Japan on 2007-10-19
Patient: 74 year old male
Adverse reactions / side effects: Confusional State, Restlessness, Hallucination, Delusion
Suspect drug(s):
Comtan
Dosage: see image
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-07-07
End date: 2007-08-07
Comtan
Dosage: see image
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-08-08
End date: 2007-08-15
Comtan
Dosage: see image
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-08-20
Pramipexole Dihydrochloride
Dosage: 1.5 mg; 3 mg; 1.5 mg, 3 mg
Administration route: Oral
End date: 2007-08-01
Pramipexole Dihydrochloride
Dosage: 1.5 mg; 3 mg; 1.5 mg, 3 mg
Administration route: Oral
Start date: 2007-08-01
End date: 2007-08-16
Pramipexole Dihydrochloride
Dosage: 1.5 mg; 3 mg; 1.5 mg, 3 mg
Administration route: Oral
Start date: 2007-08-17
End date: 2007-08-26
Pramipexole Dihydrochloride
Dosage: 1.5 mg; 3 mg; 1.5 mg, 3 mg
Administration route: Oral
Start date: 2007-08-27
Other drugs received by patient: Carbidopa and Levodopa; Madopar; FP
Adverse event in 57 year old male receiving Comtan (Entacapone)
Reported by a physician from Japan on 2007-10-18
Patient: 57 year old male
Adverse reactions / side effects: Incoherent, Mental Impairment, Psychiatric Symptom, Abnormal Behaviour
Adverse event resulted in: hospitalization
Suspect drug(s):
Artane
Dosage: 2 mg, tid
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Comtan
Dosage: 100 mg, tid
Administration route: Oral
Indication: Drug Effect Decreased
Start date: 2007-07-19
FP
Dosage: 2.5 mg, tid
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-06-14
Menesit
Dosage: 100 mg, 5qd
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Requip
Dosage: 2 mg, tid
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Rivotril
Dosage: 2 mg, tid
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Other drugs received by patient: Ternelin; Milmag
Adverse event in 70 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Italy on 2007-10-16
Patient: 70 year old male
Adverse reactions / side effects: Completed Suicide
Adverse event resulted in: death
Suspect drug(s):
Apomorphine Hydrochloride
Dosage: 28.8 mg/day
Indication: Parkinson's Disease
Start date: 2007-01-23
End date: 2007-10-01
Comtan
Dosage: 1400 mg/day
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2002-04-24
End date: 2007-10-01
Madopar
Dosage: 1025 mg/day
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2001-11-13
End date: 2007-10-02
Other drugs received by patient: Lexotan
Adverse event in 62 year old female receiving Comtan (Entacapone)
Reported by a physician from Japan on 2007-10-16
Patient: 62 year old female, weighing 43.0 kg (94.6 pounds)
Adverse reactions / side effects: Hypertension, Cerebral Haemorrhage
Adverse event resulted in: death
Suspect drug(s):
Comtan
Dosage: 300 mg/day
Administration route: Oral
Indication: Drug Effect Decreased
Start date: 2007-07-06
Dopacol
Dosage: 4.5 df/d
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2002-04-05
End date: 2002-11-07
Dopacol
Dosage: 5 df/d
Administration route: Oral
Start date: 2002-11-08
End date: 2004-01-14
Dopacol
Dosage: 5.5 df/d
Administration route: Oral
Start date: 2004-01-15
End date: 2004-10-21
Dopacol
Dosage: 6.5 df/d
Administration route: Oral
Start date: 2004-10-22
End date: 2006-01-05
Dopacol
Dosage: 8 df/d
Administration route: Oral
Start date: 2006-01-06
End date: 2007-04-19
Dopacol
Dosage: 7 df/d
Administration route: Oral
Start date: 2007-04-20
End date: 2007-07-05
Dopacol
Dosage: 6 df/d
Administration route: Oral
Start date: 2007-07-06
Other drugs received by patient: Ferromia
Adverse event in 84 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Canada on 2007-10-15
Patient: 84 year old male
Adverse reactions / side effects: Dysphagia, Fall
Adverse event resulted in: hospitalization
Suspect drug(s):
Comtan (Entacapone)
Other drugs received by patient: Sinemet
Adverse event in 74 year old female receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-15
Patient: 74 year old female
Adverse reactions / side effects: Somnolence, Sudden Onset of Sleep
Suspect drug(s):
Comtan (Entacapone)
Other drugs received by patient: Symmetrel; Sifrol; Dopacol; Boidan
Adverse event in 62 year old female receiving Comtan (Entacapone)
Reported by a physician from Japan on 2007-10-15
Patient: 62 year old female, weighing 56.0 kg (123.2 pounds)
Adverse reactions / side effects: Cardio-Respiratory Arrest, Intubation, Fall, Cardiac Disorder, Resuscitation, Shock
Adverse event resulted in: death
Suspect drug(s):
Alfarol
Dosage: 0.5 ug/day
Administration route: Oral
Clonazepam
Dosage: 1 mg/day
Administration route: Oral
Indication: Hypoaesthesia
Comtan
Dosage: 100 mg, tid
Administration route: Oral
Indication: Drug Effect Decreased
Start date: 2007-08-09
Depas
Dosage: 0.5 mg/d
Administration route: Oral
Indication: Insomnia
End date: 2007-09-01
Dops
Dosage: 300 mg/d
Administration route: Oral
Indication: Hypotension
Start date: 1993-02-24
LAC B
Dosage: 3 g/day
Administration route: Oral
Indication: Constipation
Start date: 2003-07-15
Maglax
Dosage: 990 mg/day
Administration route: Oral
Indication: Constipation
Neodopasol
Dosage: 300 mg/d
Administration route: Oral
Indication: Parkinson's Disease
Start date: 1993-06-03
Pantosin
Dosage: 300 mg/day
Administration route: Oral
Indication: Constipation
Pramipexole Dihydrochloride
Dosage: 1.5 mg/d
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2005-07-07
Other drugs received by patient: FP
Adverse event in 71 year old male receiving Comtan (Entacapone)
Reported by a physician from Japan on 2007-10-11
Patient: 71 year old male
Adverse reactions / side effects: Blood Pressure Systolic Increased, Palpitations, Tachycardia, Blood Pressure Fluctuation
Suspect drug(s):
Comtan (Entacapone)
Adverse event in 72 year old male receiving Comtan (Entacapone)
Reported by a physician from Japan on 2007-10-11
Patient: 72 year old male
Adverse reactions / side effects: Pneumonia Aspiration, Somnolence, Cough
Adverse event resulted in: hospitalization
Suspect drug(s):
Comtan (Entacapone)
Other drugs received by patient: NEO Dopaston; Cabergoline; Warfarin Sodium
Adverse event in 57 year old male receiving Comtan (Entacapone)
Reported by a physician from Japan on 2007-10-10
Patient: 57 year old male
Adverse reactions / side effects: Incoherent, Mental Impairment, Psychiatric Symptom, Abnormal Behaviour
Adverse event resulted in: hospitalization
Suspect drug(s):
Artane
Dosage: 2 mg, tid
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Comtan
Dosage: 100 mg, tid
Administration route: Oral
Indication: Drug Effect Decreased
Start date: 2007-07-19
FP
Dosage: 2.5 mg, tid
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-06-14
Menesit
Dosage: 100 mg, 5qd
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Requip
Dosage: 2 mg, tid
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Rivotril
Dosage: 2 mg, tid
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-04-14
Other drugs received by patient: Ternelin; Milmag
Adverse event in 65 year old male receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-09
Patient: 65 year old male
Adverse reactions / side effects: Nasopharyngitis, Diarrhoea, Hypokalaemia
Suspect drug(s):
Comtan
Dosage: 200 mg (100 mg, 2 in 1 d) oral, 300 mg (100 mg, 3 in 1n 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-07-10
End date: 2007-08-13
Comtan
Dosage: 200 mg (100 mg, 2 in 1 d) oral, 300 mg (100 mg, 3 in 1n 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-08-14
End date: 2007-09-04
Other drugs received by patient: Menesit
Adverse event in 62 year old female receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from Japan on 2007-10-09
Patient: 62 year old female
Adverse reactions / side effects: Wheelchair User, General Physical Health Deterioration, Sudden Death, Cardiogenic Shock, Chest Injury, Fall, Haemolysis, Organ Failure, Cardio-Respiratory Arrest
Adverse event resulted in: death
Suspect drug(s):
Comtan
Dosage: 300 mg (100 mg, 3 in 1 d) oral
Administration route: Oral
Indication: Parkinson's Disease
Start date: 2007-08-09
Pantosin
Dosage: 300 mg oral
Administration route: Oral
Other drugs received by patient: BI-Sifrol; Neodopasol; Dops; Depas; Clonazepam; Maglax; LAC B; Alfarol
Adverse event in male receiving Comtan (Entacapone)
Reported by a pharmacist from United States on 2007-10-09
Patient: male
Adverse reactions / side effects: Drug Ineffective, Paralysis
Suspect drug(s):
Comtan (Entacapone)
Adverse event in 70 year old female receiving Comtan (Entacapone)
Reported by a individual with unspecified qualification from United States on 2007-10-09
Patient: 70 year old female
Adverse reactions / side effects: Blood Pressure Increased, Hot Flush, Palpitations, Feeling Jittery, Vision Blurred
Suspect drug(s):
Comtan (Entacapone)
Other drugs received by patient: Sinemet; Pramipexole (Unknown); Selegiline (Unknown); Trihexyphenidyl HCL; Amlodipine; Metoprolol Slow Release (Unknown); Etodolac (Unknown); Protriptyline (Unknown); Loperamide (Unknown); MVI (Unknown)
|
