|
This is an index of reports of adverse events (side effects, adverse reactions, etc.) related to Combivir (Lamivudine / Zidovudine). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the side effect / adverse reaction. Or scroll down to view a sample of recent reports further on this page.
Our database includes reports from Jan 2007 to Dec 2007. The information is not vetted and should not be cosidered as verified clinical evidence.
All cases (389)
Cases resulting in a serious event (386)
Cases resulting in death (22)
Cases resulting in life threatening events (35)
Cases resulting in hospitalization (99)
Cases resulting in disability (30)
Cases resulting in other serious reactions (209)
Below is a sample of reports where side effects / adverse reactions may be related to Combivir (Lamivudine / Zidovudine). For a complete list and/or a specific selection of reports, please use the links in the index above.
Adverse event in 29 year old female receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from Botswana on 2007-10-29
Patient: 29 year old female, weighing 67.0 kg (147.4 pounds)
Adverse reactions / side effects: Intra-Uterine Death, Proteinuria, Stillbirth, PRE-Eclampsia
Adverse event resulted in: life threatening event
Suspect drug(s):
Combivir
Dosage: 450mg twice per day
Administration route: Oral
Indication: Antiviral Prophylaxis
Start date: 2007-08-17
Nevirapine
Dosage: 200mg twice per day
Administration route: Oral
Indication: Antiviral Prophylaxis
Start date: 2007-08-17
Adverse event in receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from United Kingdom on 2007-10-26
Patient:
Adverse reactions / side effects: Microcytic Anaemia
Suspect drug(s):
Septra
Nevirapine
Administration route: Oral
Indication: Prophylaxis Against HIV Infection
Combivir
Dosage: 1 tablet, qd
Indication: Prophylaxis Against HIV Infection
Adverse event in male receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from United States on 2007-10-26
Patient: male, weighing 0.1 kg (0.2 pounds)
Adverse reactions / side effects: Polydactyly, Drug Exposure During Pregnancy
Suspect drug(s):
Viracept
Dosage: daily dose:2500mg
Indication: HIV Infection
Combivir
Dosage: daily dose:900mg
Indication: HIV Infection
Start date: 2007-02-15
Adverse event in 28 year old male receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from United Kingdom on 2007-10-25
Patient: 28 year old male
Adverse reactions / side effects: Drug Toxicity
Suspect drug(s):
Combivir
Indication: HIV Infection
Efavirenz
Indication: HIV Infection
Adverse event in 54 year old female receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from United Kingdom on 2007-10-25
Patient: 54 year old female
Adverse reactions / side effects: Lipoatrophy
Suspect drug(s):
Combivir
Indication: HIV Infection
Efavirenz
Indication: HIV Infection
Adverse event in female receiving Combivir (Lamivudine / Zidovudine)
Reported by a consumer/non-health professional from United States on 2007-10-24
Patient: female
Adverse reactions / side effects: Type 2 Diabetes Mellitus
Suspect drug(s):
Sustiva
Combivir
Dosage: patient received combivir tablet for a period of 8 years.
Adverse event in 35 year old female receiving Combivir (Lamivudine / Zidovudine)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-24
Patient: 35 year old female
Adverse reactions / side effects: Drug Exposure During Pregnancy, Blighted Ovum, Abortion Induced
Suspect drug(s):
Combivir (Lamivudine / Zidovudine)
Other drugs received by patient: Reyataz; Ritonavir; Acyclovir; Folate
Adverse event in receiving Combivir (Lamivudine / Zidovudine)
Reported by a consumer/non-health professional from United States on 2007-10-23
Patient:
Adverse reactions / side effects: Anaemia
Suspect drug(s):
Septra
Zidovudine
Dosage: 10 mg/ml, unk
Administration route: Oral
Indication: Prophylaxis Against HIV Infection
Lamivudine
Dosage: 10 mg/ml, unk
Administration route: Oral
Indication: Prophylaxis Against HIV Infection
Nevirapine
Dosage: 50 mg/ml, unk
Administration route: Oral
Indication: Prophylaxis Against HIV Infection
Combivir
Dosage: 150/300 mg
Indication: Prophylaxis Against HIV Infection
Lamivudine
Dosage: 150 mg, unk
Stavudine
Indication: Prophylaxis Against HIV Infection
Kaletra
Dosage: 50 mg/200 mg
Indication: Prophylaxis Against HIV Infection
Nevirapine
Dosage: 200 mg, unk
Nelfinavir Mesilate
Dosage: unk, unk
Indication: Prophylaxis Against HIV Infection
Adverse event in 7 month old female receiving Combivir (Lamivudine / Zidovudine)
Reported by a individual with unspecified qualification on 2007-10-23
Patient: 7 month old female, weighing 5.0 kg (11.0 pounds)
Adverse reactions / side effects: Underweight, Metabolic Acidosis, Grunting, Rhinitis, Acidosis, Pallor, Eating Disorder, Vitamin B12 Deficiency, Drug Exposure During Pregnancy, Methylmalonic Aciduria, Depressed Level of Consciousness, Ammonia Increased, Foetal Growth Retardation, Lethargy
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Viramune
Indication: Retroviral Infection
Start date: 2005-09-22
End date: 2006-05-09
Viramune
Administration route: Oral
Combivir
Indication: HIV Infection
Start date: 2005-09-01
Zidovudine
Indication: Prophylaxis Against HIV Infection
Start date: 2006-07-01
End date: 2006-08-01
Ferrous Sulfate TAB
Adverse event in 7 month old female receiving Combivir (Lamivudine / Zidovudine)
Reported by a individual with unspecified qualification on 2007-10-19
Patient: 7 month old female, weighing 5.0 kg (11.0 pounds)
Adverse reactions / side effects: Underweight, Grunting, Rhinitis, Acidosis, Pallor, Eating Disorder, Vitamin B12 Deficiency, Methylmalonic Aciduria, Ammonia Increased, Depressed Level of Consciousness, Foetal Growth Retardation, Lethargy
Adverse event resulted in: hospitalization
Suspect drug(s):
Viramune
Indication: Retroviral Infection
Start date: 2005-09-22
End date: 2006-05-09
Viramune
Administration route: Oral
Combivir
Indication: HIV Infection
Start date: 2005-09-01
Zidovudine
Indication: Prophylaxis Against HIV Infection
Start date: 2006-07-01
End date: 2006-08-01
Ferrous Sulfate TAB
Adverse event in male receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from United States on 2007-10-17
Patient: male, weighing 2.6 kg (5.7 pounds)
Adverse reactions / side effects: Congenital Toxoplasmosis
Suspect drug(s):
Invirase
Indication: HIV Infection
Start date: 2002-05-23
Combivir
Indication: HIV Infection
Start date: 2002-02-12
Kaletra
Indication: HIV Infection
Start date: 2002-02-12
AZT
Indication: HIV Infection
Start date: 2002-06-10
End date: 2002-06-20
Adverse event in 22 year old female receiving Combivir (Lamivudine / Zidovudine)
Reported by a consumer/non-health professional from United States on 2007-10-16
Patient: 22 year old female
Adverse reactions / side effects: Intra-Uterine Death, Stillbirth
Suspect drug(s):
Combivir (Lamivudine / Zidovudine)
Other drugs received by patient: Viracept
Adverse event in receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from Malawi on 2007-10-16
Patient:
Adverse reactions / side effects: Alanine Aminotransferase Abnormal
Suspect drug(s):
Zidovudine
Administration route: Oral
Indication: Antiviral Prophylaxis
Lamivudine
Administration route: Oral
Indication: Antiviral Prophylaxis
Nevirapine
Administration route: Oral
Indication: Antiviral Prophylaxis
Combivir
Indication: Antiviral Prophylaxis
Lamivudine
Stavudine
Indication: Antiviral Prophylaxis
Nelfinavir
Indication: Antiviral Prophylaxis
Kaletra
Indication: Antiviral Prophylaxis
Nevirapine
Adverse event in 30 year old male receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from Mexico on 2007-10-16
Patient: 30 year old male, weighing 70.0 kg (154.0 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Lactate Dehydrogenase Increased
Suspect drug(s):
Combivir
Dosage: 2tab per day
Administration route: Oral
Start date: 2006-09-20
End date: 2007-06-28
Blinded Trial Medication
Dosage: 2u per day
Administration route: Oral
Start date: 2006-09-20
End date: 2007-06-28
Adverse event in male receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from France on 2007-10-16
Patient: male
Adverse reactions / side effects: Death
Adverse event resulted in: death
Suspect drug(s):
Viracept
Dosage: text:3 x per 1 day
Administration route: Oral
Start date: 1997-12-15
End date: 2007-06-08
Combivir
Dosage: text:2 x per 1 day
Administration route: Oral
Start date: 2007-06-08
End date: 2007-07-15
Kaletra
Dosage: text:2 x per 1 day
Administration route: Oral
Start date: 2007-06-08
End date: 2007-07-15
Other drugs received by patient: Elisor; Kardegic; ALL Other Therapeutic Products
Adverse event in female receiving Combivir (Lamivudine / Zidovudine)
Reported by a pharmacist from United Kingdom on 2007-10-16
Patient: female
Adverse reactions / side effects: Drug Exposure During Pregnancy, Ventricular Septal Defect
Suspect drug(s):
Combivir (Lamivudine / Zidovudine)
Other drugs received by patient: Unknown Medication; Iron Supplements
Adverse event in 52 year old male receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from France on 2007-10-15
Patient: 52 year old male
Adverse reactions / side effects: Optic Neuritis Retrobulbar
Adverse event resulted in: disablity
Suspect drug(s):
Invirase
Dosage: reported dosing amount: 4 doses daily.
Start date: 2006-06-23
Invirase
Start date: 2002-03-18
Bactrim DS
Dosage: also received on 28 september 2005 and 23 june 2006.
Indication: Drug USE FOR Unknown Indication
Start date: 1998-10-27
Combivir
Dosage: reported dosing amount: 2 doses daily.
Start date: 2005-09-28
End date: 2006-06-23
Combivir
Start date: 1999-05-11
End date: 1999-08-01
Combivir
Start date: 2001-03-23
Telzir
Dosage: reported dosing amount: 2 doses daily. also received on 17 june 2005.
Start date: 2005-03-29
End date: 2006-06-23
Norvir
Dosage: also received on 15 october 2004, 29 march 2005, 28 september 2005, 17 june 2005 and 23 june 2006.
Start date: 2004-04-17
Norvir
Start date: 1999-09-21
Norvir
Start date: 2000-06-06
Norvir
Start date: 2001-03-23
Norvir
Start date: 2002-03-18
Neurontin
Indication: Trigeminal Neuralgia
Start date: 2006-01-01
Lyrica
Indication: Trigeminal Neuralgia
Start date: 2006-06-23
Retrovir
Indication: Drug USE FOR Unknown Indication
Start date: 2006-06-23
Retrovir
Start date: 2005-06-17
Viread
Indication: Drug USE FOR Unknown Indication
Start date: 2006-06-23
Viread
Start date: 2003-01-03
Viread
Start date: 2003-09-12
Viread
Start date: 2004-04-17
Viread
Start date: 2004-10-15
Viread
Start date: 2005-03-29
Viread
Start date: 2005-06-17
Other drugs received by patient: Sustiva; Videx; Videx; Videx; Zerit; Zerit; Zerit; Zerit; Hivid; Hivid; Crixivan; Crixivan; 1 Concomitant Drug; Epivir; Agenerase; Kaletra; Kaletra; Fuzeon; Fuzeon; 1 Concomitant Drug; 1 Concomitant Drug; Ziagen; Tercian; Laroxyl; Tenofovir
Adverse event in male receiving Combivir (Lamivudine / Zidovudine)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-15
Patient: male
Adverse reactions / side effects: Abdominal Hernia, Cardiac Murmur, Cryptorchism, Abdominal Distension
Suspect drug(s):
Viread
Indication: HIV Infection
Start date: 2004-06-01
End date: 2004-07-20
Combivir
Indication: HIV Infection
Start date: 2004-01-30
End date: 2004-06-01
Viracept
Indication: HIV Infection
Start date: 2004-01-30
End date: 2004-07-20
Kaletra
Indication: HIV Infection
Start date: 2004-06-01
Retrovir
Indication: HIV Infection
Start date: 2004-06-01
End date: 2004-07-20
Other drugs received by patient: Folic Acid
Adverse event in 46 year old male receiving Combivir (Lamivudine / Zidovudine)
Reported by a health professional (non-physician/pharmacist) from France on 2007-10-15
Patient: 46 year old male, weighing 60.0 kg (132.0 pounds)
Adverse reactions / side effects: Coronary Artery Disease
Adverse event resulted in: disablity
Suspect drug(s):
Zerit
Indication: HIV Infection
Start date: 1998-12-30
End date: 2004-10-25
Invirase
Indication: HIV Infection
Start date: 1998-12-30
End date: 2004-10-25
Combivir
Indication: HIV Infection
Start date: 2005-01-31
End date: 2005-09-21
Kaletra
Indication: HIV Infection
Start date: 2005-01-31
Trizivir
Indication: HIV Infection
Start date: 2005-09-21
Norvir
Indication: HIV Infection
Start date: 2006-01-11
Adverse event in 30 year old male receiving Combivir (Lamivudine / Zidovudine)
Reported by a consumer/non-health professional from United States on 2007-10-12
Patient: 30 year old male, weighing 70.0 kg (154.0 pounds)
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Blood Lactate Dehydrogenase Increased, Hepatic Enzyme Increased
Suspect drug(s):
Efavirenz
Administration route: Oral
Indication: HIV Test Positive
Start date: 2007-04-26
End date: 2007-06-28
Combivir
Administration route: Oral
Indication: HIV Test Positive
Start date: 2007-04-26
End date: 2007-06-28
Adverse event in male receiving Combivir (Lamivudine / Zidovudine)
Reported by a individual with unspecified qualification from United States on 2007-10-12
Patient: male
Adverse reactions / side effects: Congenital Toxoplasmosis, Cerebral Ventricle Dilatation, Hepatosplenomegaly
Suspect drug(s):
Kaletra
Indication: Drug Exposure During Pregnancy
Invirase
Indication: Drug Exposure During Pregnancy
Combivir
Indication: Drug Exposure During Pregnancy
Retrovir
Indication: Drug Exposure During Pregnancy
Adverse event in 44 year old male receiving Combivir (Lamivudine / Zidovudine)
Reported by a consumer/non-health professional from France on 2007-10-11
Patient: 44 year old male
Adverse reactions / side effects: Optic Atrophy, Glaucoma, Optic Nerve Disorder, Drug Ineffective, Tooth Abscess, Trigeminal Neuralgia, Sciatica, Tooth Extraction, Visual Acuity Reduced, Treatment Noncompliance, Balance Disorder, Leukoencephalopathy, Depression, Optic Neuritis Retrobulbar, Facial Pain, Mononeuropathy Multiplex, Visual Disturbance, Gastrointestinal Disorder, Memory Impairment, Neuralgia
Adverse event resulted in: hospitalization, disablity
Suspect drug(s):
Retrovir
Indication: HIV Infection
Start date: 2006-06-23
Telzir
Indication: HIV Infection
Start date: 2005-03-29
End date: 2006-06-23
Combivir
Indication: HIV Infection
Start date: 2005-09-28
End date: 2006-06-23
Epivir
Indication: HIV Infection
Start date: 1998-04-01
Viread
Indication: HIV Infection
Start date: 2006-06-23
Invirase
Indication: HIV Infection
Start date: 2006-06-23
Lyrica
Indication: Trigeminal Neuralgia
Start date: 2006-06-23
End date: 2006-07-01
Neurontin
Indication: Trigeminal Neuralgia
Start date: 2006-01-01
End date: 2006-01-01
Bactrim
Start date: 1998-09-01
Norvir
Indication: HIV Infection
Start date: 2004-04-17
Other drugs received by patient: Viracept; Zerit
Adverse event in 17 year old female receiving Combivir (Lamivudine / Zidovudine)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-10
Patient: 17 year old female
Adverse reactions / side effects: Abortion Spontaneous
Suspect drug(s):
Combivir (Lamivudine / Zidovudine)
Adverse event in male receiving Combivir (Lamivudine / Zidovudine)
Reported by a physician from France on 2007-10-09
Patient: male
Adverse reactions / side effects: Mononeuropathy Multiplex, Glaucoma, Optic Neuropathy, Trigeminal Neuralgia, Optic Neuritis Retrobulbar, Encephalopathy
Adverse event resulted in: disablity
Suspect drug(s):
Viread
Administration route: Oral
Indication: HIV Infection
Start date: 2002-03-18
Viread
Start date: 2006-06-23
Retrovir
Start date: 1992-01-01
End date: 1997-01-01
Retrovir
Start date: 2005-06-17
Bactrim
Start date: 1998-10-27
Combivir
Administration route: Oral
Indication: HIV Infection
Start date: 2000-09-01
End date: 2006-06-23
Norvir
Administration route: Oral
Indication: HIV Infection
Start date: 1999-09-21
Norvir
Administration route: Oral
Start date: 2004-04-17
Telzir
Administration route: Oral
Indication: HIV Infection
Start date: 2005-03-29
End date: 2006-06-23
Bactrim DS
Start date: 2002-03-18
Neurontin
Indication: Trigeminal Neuralgia
Start date: 2006-01-01
End date: 2006-07-20
Lyrica
Indication: Trigeminal Neuralgia
Start date: 2006-06-01
End date: 2006-07-20
Other drugs received by patient: Invirase; Invirase; Kaletra; Fuzeon; Reyataz; Ziagen; Tercian; Laroxyl
Adverse event in 46 year old male receiving Combivir (Lamivudine / Zidovudine)
Reported by a health professional (non-physician/pharmacist) from France on 2007-10-09
Patient: 46 year old male, weighing 60.0 kg (132.0 pounds)
Adverse reactions / side effects: Coronary Artery Disease
Adverse event resulted in: disablity
Suspect drug(s):
Invirase
Administration route: Oral
Indication: HIV Infection
Start date: 1998-12-30
End date: 2004-10-25
Trizivir
Administration route: Oral
Indication: HIV Infection
Start date: 2005-09-21
Kaletra
Administration route: Oral
Indication: HIV Infection
Start date: 2005-01-31
Combivir
Administration route: Oral
Indication: HIV Infection
Start date: 2005-01-31
End date: 2005-09-21
Zerit
Administration route: Oral
Indication: HIV Infection
Start date: 1998-12-30
End date: 2004-10-25
Norvir
Administration route: Oral
Indication: HIV Infection
Start date: 2006-01-11
Norvir
Administration route: Oral
Start date: 1998-12-30
End date: 2004-10-25
Other drugs received by patient: Zelitrex; Escitalopram; Seresta
|
