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This is an index of reports of adverse events (side effects, adverse reactions, etc.) related to Clozaril (Clozapine). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the side effect / adverse reaction. Or scroll down to view a sample of recent reports further on this page.
Our database includes reports from Jan 2007 to Dec 2007. The information is not vetted and should not be cosidered as verified clinical evidence.
All cases (396)
Cases resulting in a serious event (392)
Cases resulting in death (66)
Cases resulting in life threatening events (32)
Cases resulting in hospitalization (150)
Cases resulting in disability (20)
Cases resulting in other serious reactions (271)
Below is a sample of reports where side effects / adverse reactions may be related to Clozaril (Clozapine). For a complete list and/or a specific selection of reports, please use the links in the index above.
Adverse event in 39 year old male receiving Clozaril (Clozapine)
Reported by a physician from United Kingdom on 2007-10-29
Patient: 39 year old male
Adverse reactions / side effects: Electrocardiogram T Wave Amplitude Decreased, Tachycardia, Chest Pain, Circulatory Collapse, Myocarditis, Cardiomegaly, Pericardial Effusion
Adverse event resulted in: hospitalization
Suspect drug(s):
Clozaril (Clozapine)
Other drugs received by patient: Valproate Sodium
Adverse event in male receiving Clozaril (Clozapine)
Reported by a consumer/non-health professional from United States on 2007-10-29
Patient: male
Adverse reactions / side effects: Therapeutic Agent Toxicity, Dehydration
Adverse event resulted in: death
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 63 year old female receiving Clozaril (Clozapine)
Reported by a physician from Australia on 2007-10-29
Patient: 63 year old female
Adverse reactions / side effects: Drug Level Below Therapeutic, Condition Aggravated, Neutropenia, Convulsion, Leukopenia
Adverse event resulted in: hospitalization
Suspect drug(s):
Clozaril
Dosage: 0 - 700mg daily
Indication: Schizophrenia
Start date: 1995-09-15
End date: 1999-05-25
Clozaril
Dosage: 0 - 350mg daily
Start date: 2001-11-23
End date: 2007-04-02
Clozaril
Dosage: 200mg daily
Start date: 2007-04-02
End date: 2007-09-19
Other drugs received by patient: Flixotide; Acimax; Losec
Adverse event in 47 year old male receiving Clozaril (Clozapine)
Reported by a individual with unspecified qualification from United States on 2007-10-29
Patient: 47 year old male
Adverse reactions / side effects: Pneumonia, Myocardial Infarction
Adverse event resulted in: death
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 22 year old female receiving Clozaril (Clozapine)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-26
Patient: 22 year old female
Adverse reactions / side effects: Weight Increased, Petechiae, Skin Striae
Suspect drug(s):
Lustral
Administration route: Oral
Indication: Depressed Mood
Clozaril
Administration route: Oral
Indication: Schizophrenia
Start date: 2002-01-22
End date: 2002-08-01
Adverse event in male receiving Clozaril (Clozapine)
Reported by a health professional (non-physician/pharmacist) from Australia on 2007-10-26
Patient: male
Adverse reactions / side effects: Tachycardia, Heart Rate Increased, Bundle Branch Block, Electrocardiogram Abnormal, Sinus Tachycardia
Suspect drug(s):
Clozaril
Dosage: up to 100 mg/day
Administration route: Oral
Start date: 2005-11-16
End date: 2005-12-01
Clozaril
Dosage: 12.5 - 75 mg per day
Start date: 2006-02-13
End date: 2006-02-20
Clozaril
Dosage: 12.5mg per day
Start date: 2007-10-22
Adverse event in 53 year old male receiving Clozaril (Clozapine)
Reported by a pharmacist from Australia on 2007-10-25
Patient: 53 year old male
Adverse reactions / side effects: Neutrophil Count Increased, Pleural Effusion, White Blood Cell Count Increased, Lower Respiratory Tract Infection
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in male receiving Clozaril (Clozapine)
Reported by a individual with unspecified qualification from Canada on 2007-10-24
Patient: male
Adverse reactions / side effects: Dysstasia, Heart Rate Increased, Blood Pressure Decreased, Feeling Abnormal
Adverse event resulted in: life threatening event
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 56 year old female receiving Clozaril (Clozapine)
Reported by a physician from United Kingdom on 2007-10-23
Patient: 56 year old female
Adverse reactions / side effects: Confusional State, Blood Creatine Phosphokinase Increased, C-Reactive Protein Increased, Body Temperature Increased, Neuroleptic Malignant Syndrome, Somnolence, Muscle Rigidity
Suspect drug(s):
Clozaril (Clozapine)
Other drugs received by patient: Citalopram Hydrobromide; Quetiapine Fumarate; Ramipril; Atenolol; Trifluoperazine
Adverse event in 49 year old male receiving Clozaril (Clozapine)
Reported by a physician from United Kingdom on 2007-10-23
Patient: 49 year old male, weighing 88.0 kg (193.6 pounds)
Adverse reactions / side effects: Overdose, Sedation, Hypersomnia
Suspect drug(s):
Cipralex
Clozaril
Dosage: 450 mg/day
Administration route: Oral
Indication: Schizophrenia
Start date: 2005-07-11
Clozaril
Dosage: 1700 mg overdose
Administration route: Oral
Start date: 2005-10-08
Clozaril
Dosage: overdose - 3 days supply
Administration route: Oral
Abilify
Dosage: overdose - 3 days supply
Mirtazapine
Dosage: overdose - 3 days supply
Adverse event in male receiving Clozaril (Clozapine)
Reported by a individual with unspecified qualification from NEW Zealand on 2007-10-22
Patient: male
Adverse reactions / side effects: Cardio-Respiratory Arrest, Anorexia
Adverse event resulted in: death
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 27 year old male receiving Clozaril (Clozapine)
Reported by a physician from United Kingdom on 2007-10-22
Patient: 27 year old male
Adverse reactions / side effects: Haemoglobin Decreased, Diarrhoea, Anaemia
Suspect drug(s):
Clozaril
Dosage: unk, unk
Administration route: Oral
Indication: Schizophrenia
Start date: 2002-03-19
Clozaril
Dosage: 450mg/day
Administration route: Oral
Start date: 2005-01-01
Adverse event in 35 year old female receiving Clozaril (Clozapine)
Reported by a individual with unspecified qualification from United States on 2007-10-22
Patient: 35 year old female, weighing 83.5 kg (183.6 pounds)
Adverse reactions / side effects: Akathisia, Confusional State, Hallucination, Auditory, Paralysis, Pallor, Somnolence, Fatigue, Dizziness, Musculoskeletal Stiffness, Depression, Heart Rate Irregular, Nervousness, Blood Pressure Increased, Dyspnoea, Dysphagia, Drooling, Restlessness, Abnormal Behaviour, Tremor, Anxiety, Heart Rate Increased, Blood Pressure Decreased, Drug Dependence, Asthenia
Adverse event resulted in: life threatening event
Suspect drug(s):
Clozaril
Dosage: 400 mgs at bedtime oral
Administration route: Oral
Indication: Asperger's Disorder
Clozaril
Dosage: 400 mgs at bedtime oral
Administration route: Oral
Indication: Hallucination, Auditory
Other drugs received by patient: Supplements; Multi-Vitamin; Omega 3; Taurine; Magnesium Sulfate; Zinc; Vita D
Adverse event in 59 year old male receiving Clozaril (Clozapine)
Reported by a pharmacist from Australia on 2007-10-19
Patient: 59 year old male
Adverse reactions / side effects: RED Cell Distribution Width Increased, Pneumonia Aspiration, Intestinal Obstruction, Neutrophil Count Decreased, Constipation, Lymphocyte Count Decreased
Adverse event resulted in: hospitalization
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 39 year old male receiving Clozaril (Clozapine)
Reported by a physician from United Kingdom on 2007-10-19
Patient: 39 year old male
Adverse reactions / side effects: Electrocardiogram T Wave Amplitude Decreased, Tachycardia, Circulatory Collapse, Cardiomegaly, Pericardial Effusion
Adverse event resulted in: hospitalization
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 39 year old male receiving Clozaril (Clozapine)
Reported by a individual with unspecified qualification from Ireland on 2007-10-19
Patient: 39 year old male
Adverse reactions / side effects: White Blood Cell Count Decreased, Mental Impairment, Platelet Count Decreased, Neutrophil Count Decreased, Lymphocyte Count Decreased
Suspect drug(s):
Clozaril
Dosage: unk, unk
Administration route: Oral
Indication: Schizophrenia
Start date: 1994-01-01
End date: 2007-06-01
Clozaril
Dosage: 550 mg, qd
Administration route: Oral
Start date: 2007-07-25
Solian
Start date: 2007-09-01
Adverse event in 20 year old male receiving Clozaril (Clozapine)
Reported by a health professional (non-physician/pharmacist) from Canada on 2007-10-19
Patient: 20 year old male
Adverse reactions / side effects: Blood Creatine Phosphokinase Increased, Hyperpyrexia, Urinary Incontinence, Stupor, Convulsion, Myalgia, Eye Rolling, Sepsis, Neuroleptic Malignant Syndrome, Gait Disturbance
Suspect drug(s):
Seroquel
Administration route: Oral
Clozaril
Administration route: Oral
Other drugs received by patient: Allertec; Clonazepam
Adverse event in 61 year old male receiving Clozaril (Clozapine)
Reported by a physician from Ireland on 2007-10-19
Patient: 61 year old male
Adverse reactions / side effects: Urinary Tract Infection, Pyrexia, Blood Pressure Fluctuation
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 70 year old female receiving Clozaril (Clozapine)
Reported by a pharmacist from United Kingdom on 2007-10-19
Patient: 70 year old female
Adverse reactions / side effects: Urinary Tract Infection
Adverse event resulted in: hospitalization
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 63 year old female receiving Clozaril (Clozapine)
Reported by a physician from Australia on 2007-10-18
Patient: 63 year old female
Adverse reactions / side effects: Drug Level Below Therapeutic, Condition Aggravated, Neutropenia, Convulsion, Leukopenia
Adverse event resulted in: hospitalization
Suspect drug(s):
Clozaril
Dosage: 0 - 700mg daily
Indication: Schizophrenia
Start date: 1995-09-15
End date: 1999-05-25
Clozaril
Dosage: 0 - 350mg daily
Start date: 2001-11-23
End date: 2007-04-02
Clozaril
Dosage: 200mg daily
Start date: 2007-04-02
End date: 2007-09-19
Other drugs received by patient: Flixotide; Acimax; Losec
Adverse event in 72 year old male receiving Clozaril (Clozapine)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-18
Patient: 72 year old male
Adverse reactions / side effects: Diabetes Mellitus, Restless Legs Syndrome, Myelodysplastic Syndrome, Platelet Count Increased, Pyrexia, Pallor, Gastritis, Lower Respiratory Tract Infection, Fatigue, Malaise, Aspiration, Oesophagitis, RED Blood Cell Count Decreased, Sedation, Dizziness, Crepitations, Cough, White Blood Cell Count Increased, Neutrophil Count Increased, Pneumonia, Polyp, Mental Impairment, Haemoglobin Decreased, Anorexia, Depressed Level of Consciousness, Gait Disturbance, Sputum Discoloured, Tardive Dyskinesia
Adverse event resulted in: hospitalization, disablity
Suspect drug(s):
Aripiprazole
Dosage: 5 mg
Clozaril
Dosage: 300mg daily
Administration route: Oral
Indication: Schizophrenia
Start date: 1999-04-09
Other drugs received by patient: Clonazepam; Paracetamol; Esomeprazole; Esomeprazole; Domperidone; Aspirin; Atorvastatin Calcium; Furosemide; Gliclazide; Perindopril Erbumine; Isosorbide Mononitrate; Escitalopram Oxalate; Salbutamol
Adverse event in 65 year old female receiving Clozaril (Clozapine)
Reported by a individual with unspecified qualification from United Kingdom on 2007-10-18
Patient: 65 year old female
Adverse reactions / side effects: Lymphocyte Count Increased, Drug Level Below Therapeutic, Chronic Lymphocytic Leukaemia, Haemoglobin Decreased, Overweight, White Blood Cell Count Increased
Suspect drug(s):
Clozaril (Clozapine)
Other drugs received by patient: Lansoprazole
Adverse event in male receiving Clozaril (Clozapine)
Reported by a consumer/non-health professional from Canada on 2007-10-18
Patient: male
Adverse reactions / side effects: Heart Rate Increased, Blood Pressure Decreased, Feeling Abnormal
Adverse event resulted in: life threatening event
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in 28 year old male receiving Clozaril (Clozapine)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-18
Patient: 28 year old male
Adverse reactions / side effects: Vomiting, Aspiration
Adverse event resulted in: death
Suspect drug(s):
Clozaril (Clozapine)
Adverse event in female receiving Clozaril (Clozapine)
Reported by a physician from NEW Zealand on 2007-10-17
Patient: female
Adverse reactions / side effects: Wrong Drug Administered, Circulatory Collapse
Suspect drug(s):
Clozaril (Clozapine)
Other drugs received by patient: Chlorpromazine
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