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This is an index of adverse event reports related to Aricept (Donepezil). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the adverse reaction. Or scroll down to view a sample of recent reports further on this page.
Our database includes reports from Jan 2007 to Dec 2007. The information is not vetted and should not be cosidered as verified clinical evidence.
All cases (204)
Cases resulting in a serious event (187)
Cases resulting in death (33)
Cases resulting in life threatening events (35)
Cases resulting in hospitalization (118)
Cases resulting in disability (7)
Cases resulting in other serious reactions (47)
Below is a sample of adverse event reports reports related to Aricept (Donepezil). For a complete list and/or a specific selection of reports, please use the links in the index above.
Adverse event in female receiving Aricept (Donepezil)
Reported by a consumer/non-health professional from United States on 2007-10-30
Patient: female
Adverse reactions / side effects: Fatigue, Dementia Alzheimer's Type, Disorientation, Accidental Overdose
Suspect drug(s):
Aricept
Indication: Dementia Alzheimer's Type
Start date: 2007-07-01
Mirapex
Indication: Parkinson's Disease
Start date: 2006-11-01
Adverse event in 76 year old male receiving Aricept (Donepezil)
Reported by a physician from United States on 2007-10-26
Patient: 76 year old male, weighing 75.0 kg (165.0 pounds)
Adverse reactions / side effects: Chest Discomfort, Presyncope, Depressed Level of Consciousness, Drug Interaction, Blood Pressure Decreased
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Dosage: 5 mg, 1 in 1 d, oral; 10 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Dementia
End date: 2007-09-11
Aricept
Dosage: 5 mg, 1 in 1 d, oral; 10 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Dementia
Start date: 2007-09-12
Seroquel
Dosage: 12.5 mg, 1 in 1 d, oral
Administration route: Oral
End date: 2007-09-14
Other drugs received by patient: Sinemet; Entacapone (Entacapone); Tolcapone (Tolcapone); Coumadin; Imdur; Zoloft; Circline; Lasix; Pravastatin
Adverse event in 66 year old female receiving Aricept (Donepezil)
Reported by a physician from Japan on 2007-10-26
Patient: 66 year old female
Adverse reactions / side effects: Hepatic Function Abnormal, Metabolic Acidosis, Drug Ineffective, Disseminated Intravascular Coagulation, LIP Haemorrhage, Nephritis, Haematemesis, Renal Failure, Respiratory Failure, Pancreatic Enzymes Increased, White Blood Cell Count Increased
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aricept
Dosage: 3 mg, 1 in 1 d, oral, 5 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Dementia Alzheimer's Type
Start date: 2003-06-29
End date: 2003-08-08
Aricept
Dosage: 3 mg, 1 in 1 d, oral, 5 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Dementia Alzheimer's Type
Start date: 2003-08-09
End date: 2005-04-03
Pegasys
Dosage: 90 mcg, 1 in 1 d, subcutaneous
Indication: Hepatitis C
Start date: 2004-04-11
End date: 2005-04-01
Adverse event in 83 year old female receiving Aricept (Donepezil)
Reported by a physician from Japan on 2007-10-26
Patient: 83 year old female, weighing 58.0 kg (127.6 pounds)
Adverse reactions / side effects: Drug Ineffective, Electrocardiogram QT Shortened, Coronary Artery Stenosis, Atrial Fibrillation, Fall, Pallor, Hypokalaemia, Convulsion, Long QT Syndrome, Torsade DE Pointes, Sick Sinus Syndrome, Depressed Level of Consciousness, Bradycardia, Sinus Arrest, Myocardial Infarction
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aricept (Donepezil)
Other drugs received by patient: Acecol (Temocapril) (Temocapril Hydrochloride); Maintate (Bisoprolol Fumarate); Coniel (Benidipine Hydrochloride); Adalat; Amlodipine Besylate; Aspirin; Diart (Azosemide)
Adverse event in 82 year old female receiving Aricept (Donepezil)
Reported by a individual with unspecified qualification from France on 2007-10-22
Patient: 82 year old female
Adverse reactions / side effects: Dyspnoea, Coagulation Factor V Level Decreased, Hepatitis, Arrhythmia, Cardiomegaly, Oedema Peripheral, Dehydration, Pleural Effusion, Increased Bronchial Secretion, Electrocardiogram Repolarisation Abnormality, Blood Creatinine Increased
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Aricept
Dosage: 10 mg qd po
Administration route: Oral
Start date: 2006-07-15
End date: 2007-05-02
Cetornan (Ornithine Oxoglurate)
Dosage: 5 g bid po
Administration route: Oral
Start date: 2007-04-01
End date: 2007-05-02
Citalopram Hydrobromide
Dosage: 20 mg qd po
Administration route: Oral
Start date: 2006-07-15
End date: 2007-05-02
Omeprazole
Start date: 2006-07-15
End date: 2007-05-02
Other drugs received by patient: Silomat (Clobutinol Hydrochloride); Aldactone; NPH Insulin (Insulin Injection, Isophane); Nitriderm TTS (Glyceryl Trinitrate)
Adverse event in 89 year old female receiving Aricept (Donepezil)
Reported by a physician from Japan on 2007-10-22
Patient: 89 year old female, weighing 42.0 kg (92.4 pounds)
Adverse reactions / side effects: Eyelid Oedema, Atelectasis, Blood Bilirubin Increased, Respiratory Disorder, Hepatic Function Abnormal, Hyperkalaemia, Atrioventricular Block Complete, Sinus Bradycardia, Haematocrit Decreased, Gamma-Glutamyltransferase Increased, RED Blood Cell Count Decreased, Pleural Effusion, Blood Sodium Increased, Sinus Arrest, Blood Creatinine Increased, Blood Glucose Increased, Decreased Appetite, White Blood Cell Count Decreased, Blood Alkaline Phosphatase Increased, Blood Urea Increased, Hypotension, Blood Lactate Dehydrogenase Increased, Alanine Aminotransferase Increased, General Physical Health Deterioration, Blood Potassium Increased, Haemoglobin Decreased, Sick Sinus Syndrome, Cardiac Failure, Cardiac Pacemaker Insertion, Electrocardiogram Abnormal, Aspartate Aminotransferase Increased
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Dosage: 5mg
Administration route: Oral
Start date: 2007-03-16
Diltiazem HCL
Dosage: 100 mg/day
Administration route: Oral
Indication: Angina Pectoris
Start date: 2007-06-15
End date: 2007-08-17
Diovan
Dosage: 40 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 2007-07-20
End date: 2007-08-17
Other drugs received by patient: Famogast; Urso 250; Trepibutone; Coniel; Nitroderm; Sigmart; Lasix; Doxazosin Mesylate
Adverse event in 75 year old female receiving Aricept (Donepezil)
Reported by a individual with unspecified qualification from United States on 2007-10-16
Patient: 75 year old female, weighing 60.3 kg (132.7 pounds)
Adverse reactions / side effects: Agitation, Hallucination, Visual, Hallucination, Auditory, Dementia, Aggression
Suspect drug(s):
Aricept (Donepezil)
Adverse event in 73 year old male receiving Aricept (Donepezil)
Reported by a individual with unspecified qualification from Greece on 2007-10-15
Patient: 73 year old male, weighing 75.0 kg (165.0 pounds)
Adverse reactions / side effects: Cardiopulmonary Failure, General Physical Health Deterioration, Nodal Rhythm, Disease Progression
Adverse event resulted in: death
Suspect drug(s):
Aricept
Dosage: 10 mg; qd; po
Administration route: Oral
Start date: 2007-05-07
End date: 2007-05-19
Cubicin
Dosage: 4 mg/kg; q24h
Indication: Soft Tissue Infection
Start date: 2007-05-11
End date: 2007-05-19
Other drugs received by patient: Tazocin; Insulin Humulin; Primperan; Clexane; Saccharomyces Boulardii; Citalopram Hydrobromide; Alfuzosin Hydrochloride
Adverse event in 995 month old female receiving Aricept (Donepezil)
Reported by a health professional (non-physician/pharmacist) from France on 2007-10-12
Patient: 995 month old female
Adverse reactions / side effects: Cytolytic Hepatitis
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Aricept
Administration route: Oral
Start date: 2006-07-15
End date: 2007-05-02
Cetornan
Administration route: Oral
Start date: 2007-04-01
End date: 2007-05-02
Omeprazole
Administration route: Oral
Start date: 2006-07-15
End date: 2007-05-02
Seropram
Administration route: Oral
Start date: 2006-07-15
End date: 2007-05-02
Other drugs received by patient: Lasix; Hemigoxine; Aldactone; Insuline Profil 30; Nitroderm; Silomat
Adverse event in 82 year old female receiving Aricept (Donepezil)
Reported by a health professional (non-physician/pharmacist) from France on 2007-10-12
Patient: 82 year old female
Adverse reactions / side effects: Dyspnoea, Cytolytic Hepatitis, Dehydration, Oedema Peripheral, Acute Hepatic Failure, General Physical Health Deterioration, Heart Rate Irregular
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Aricept
Dosage: 10 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Dementia Alzheimer's Type
Start date: 2006-07-15
End date: 2007-05-02
Cetrornan (Orienthine Oxoglurate)
Dosage: 10 gm, oral
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
Start date: 2007-04-01
End date: 2007-05-02
Citalopram Hydrobromide
Dosage: 20 mg, oral
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
Start date: 2006-07-15
End date: 2007-05-02
Omeprazole
Dosage: oral
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
Start date: 2006-07-15
End date: 2007-05-02
Other drugs received by patient: Lasix; Digoxin; Aldactone; Insulin; Nitriderm (Glyceryl Trinitrate)
Adverse event in female receiving Aricept (Donepezil)
Reported by a consumer/non-health professional from United States on 2007-10-11
Patient: female
Adverse reactions / side effects: Pneumonia, Pneumonia Aspiration, Spondylolisthesis, Urinary Tract Infection, Abnormal Behaviour, Atrial Fibrillation, General Physical Health Deterioration, Platelet Count Increased, Fall, Fracture, Respiratory Failure, Blood Pressure Abnormal, Blindness
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Start date: 2003-11-01
End date: 2004-12-01
Neurontin
Indication: Agitation
Start date: 2003-11-01
End date: 2004-12-01
Other drugs received by patient: Glucotrol; Metformin HCL; Lisinopril; Insulin; Lantus; NPH Insulin; Zyprexa; Mirtazapine; Digoxin; Acetylsalicylic Acid; Ophthalmologicals
Adverse event in 90 year old female receiving Aricept (Donepezil)
Reported by a physician from Japan on 2007-10-09
Patient: 90 year old female, weighing 50.0 kg (110.0 pounds)
Adverse reactions / side effects: Dementia, Parkinsonism
Suspect drug(s):
Aricept
Dosage: 5 mg, uid/qd, oral; 5 mg/d, oral
Administration route: Oral
Indication: Dementia
Start date: 2004-07-09
End date: 2007-07-21
Aricept
Dosage: 5 mg, uid/qd, oral; 5 mg/d, oral
Administration route: Oral
Indication: Dementia
Start date: 2007-08-08
Paxil
Dosage: 20 mg, bid, oral
Administration route: Oral
Indication: Depression
Start date: 2005-09-07
End date: 2007-07-21
Vesicare
Dosage: 5 mg, uid/qd, oral; 10 mg, uid/qd,
Indication: Hypertonic Bladder
Start date: 2007-06-20
End date: 2007-07-03
Vesicare
Dosage: 5 mg, uid/qd, oral; 10 mg, uid/qd,
Indication: Hypertonic Bladder
Start date: 2007-07-04
End date: 2007-07-21
Other drugs received by patient: Calblock (Azelnidipine) Tablet; Tenormin; Blopress (Candesartan Cilexetil) Tablet
Adverse event in 79 year old female receiving Aricept (Donepezil)
Reported by a consumer/non-health professional from France on 2007-10-05
Patient: 79 year old female
Adverse reactions / side effects: Blood Urea Increased, Glossodynia, Lung Infection, Blood Osmolarity Increased, Somnolence, Miosis, Dehydration, Blood Creatinine Increased, Renal Failure Acute, Blood Glucose Increased
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Dosage: 10mg per day
Administration route: Oral
End date: 2007-08-14
Cotareg
Dosage: 1tab per day
Administration route: Oral
End date: 2007-08-14
Memantine HCL
Dosage: 10mg per day
Administration route: Oral
End date: 2007-08-14
Paroxetine
Dosage: 10mg per day
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
End date: 2007-08-14
Other drugs received by patient: Risperdal
Adverse event in 82 year old male receiving Aricept (Donepezil)
Reported by a pharmacist from Japan on 2007-10-04
Patient: 82 year old male
Adverse reactions / side effects: Blood Chloride Decreased, Hyponatraemia, Blood Sodium Decreased
Suspect drug(s):
Aricept
Dosage: 5 mg/day
Administration route: Oral
Start date: 2007-08-25
End date: 2007-09-18
Diovan
Dosage: 40 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 2006-05-26
Other drugs received by patient: Lansoprazole; Amlodipine; Depas
Adverse event in 85 year old female receiving Aricept (Donepezil)
Reported by a health professional (non-physician/pharmacist) from France on 2007-10-02
Patient: 85 year old female
Adverse reactions / side effects: Malnutrition, Dehydration, Depressed Level of Consciousness, Disorientation, Azotaemia
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Dosage: 10 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Dementia Alzheimer's Type
Start date: 2003-01-01
Aspirin
Dosage: 75 mg, oral
Administration route: Oral
Start date: 2003-01-01
Valsartan and Hydrochlorothiazide
Dosage: 80/12.5 mg, oral
Administration route: Oral
Start date: 2003-01-01
Other drugs received by patient: Digoxin; Hemidigoxine (Digoxin); Zolpidem Tartrate
Adverse event in 79 year old male receiving Aricept (Donepezil)
Reported by a health professional (non-physician/pharmacist) from France on 2007-10-02
Patient: 79 year old male
Adverse reactions / side effects: Dehydration, Lung Infection, Miosis, Blood Osmolarity Increased, Renal Failure Acute
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Dosage: 10 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Dementia Alzheimer's Type
End date: 2007-08-14
Diovan HCT
Dosage: 80/12.5 mg, oral
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
End date: 2007-08-14
Memantine HCL
Dosage: 10 mg, oral
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
End date: 2007-08-14
Paroxetine HCL
Dosage: 10 mg, oral
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
End date: 2007-08-14
Other drugs received by patient: Risperdal
Adverse event in 76 year old female receiving Aricept (Donepezil)
Reported by a physician from United Kingdom on 2007-10-02
Patient: 76 year old female
Adverse reactions / side effects: Blood Pressure Increased, Torsade DE Pointes, Essential Tremor, Bradycardia
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aricept
Dosage: 10 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Dementia Alzheimer's Type
Start date: 2003-09-01
End date: 2005-06-15
Escitalopram Oxalate
Dosage: 10 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Depression
Start date: 2005-06-09
End date: 2005-06-15
Inderal
Dosage: 80 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Anxiety
Start date: 2005-06-09
End date: 2005-06-15
Inderal
Dosage: 80 mg, 1 in 1 d, oral
Administration route: Oral
Indication: Essential Tremor
Start date: 2005-06-09
End date: 2005-06-15
Other drugs received by patient: Prochlorperazine Maleate; Omeprazole; Ferrous Sulfate TAB
Adverse event in male receiving Aricept (Donepezil)
Reported by a consumer/non-health professional from United States on 2007-07-30
Patient: male
Adverse reactions / side effects: Vomiting, Diarrhoea, Nausea, Flatulence, Apallic Syndrome
Suspect drug(s):
Aricept
Start date: 2007-02-26
End date: 2007-06-19
Dilantin
Start date: 2006-11-06
End date: 2007-02-01
Neurontin
Other drugs received by patient: Celexa
Adverse event in female receiving Aricept (Donepezil)
Reported by a consumer/non-health professional from United States on 2007-07-25
Patient: female, weighing 45.4 kg (99.8 pounds)
Adverse reactions / side effects: Blood Pressure Increased, Confusional State, Unresponsive TO Stimuli
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Dosage: daily orally
Administration route: Oral
Indication: Dementia
Seroquel
Dosage: 50 mg daily orally (25 mg, increased to 50mg)
Administration route: Oral
Indication: Anxiety
Seroquel
Dosage: 50 mg daily orally (25 mg, increased to 50mg)
Administration route: Oral
Indication: Disorientation
Other drugs received by patient: Synthroid; Digoxin
Adverse event in female receiving Aricept (Donepezil)
Reported by a physician from Austria on 2007-07-25
Patient: female, weighing 48.0 kg (105.6 pounds)
Adverse reactions / side effects: Extrapyramidal Disorder, Mobility Decreased
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
Start date: 2007-04-12
Cipralex
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
End date: 2007-04-29
Quilonorm Retard
Administration route: Oral
Indication: Depression
Start date: 2007-04-22
Risperdal
Administration route: Oral
Indication: Depression
Start date: 2007-04-02
End date: 2007-04-26
Other drugs received by patient: Abilify; Cymbalta; Edronax; Rivotril; Cerebrolysin; Nexium
Adverse event in 71 year old female receiving Aricept (Donepezil)
Reported by a physician from Austria on 2007-07-25
Patient: 71 year old female, weighing 48.0 kg (105.6 pounds)
Adverse reactions / side effects: Drug Interaction, Parkinsonism, Eating Disorder, Dysstasia, Activities of Daily Living Impaired, Musculoskeletal Stiffness, Gait Disturbance, Salivary Hypersecretion, Extrapyramidal Disorder, Mobility Decreased
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept
Dosage: 5mg per day
Administration route: Oral
Start date: 2007-04-12
End date: 2007-04-22
Cipralex
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
End date: 2007-04-29
Nexium
Dosage: 20mg per day
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
Start date: 2007-03-26
Quilonorm Retard
Administration route: Oral
Indication: Depression
Risperdal
Administration route: Oral
Start date: 2007-04-02
End date: 2007-04-26
Other drugs received by patient: Rivotril; Rivotril; Rivotril; Rivotril; Rivotril; Abilify; Cymbalta; Edronax; Cerebrolysin
Adverse event in 73 year old male receiving Aricept (Donepezil)
Reported by a health professional (non-physician/pharmacist) from Greece on 2007-07-24
Patient: 73 year old male, weighing 75.0 kg (165.0 pounds)
Adverse reactions / side effects: Cardiopulmonary Failure, Nodal Rhythm
Adverse event resulted in: death
Suspect drug(s):
Aricept
Dosage: 10 mg, 1 in 1 d, oral
Administration route: Oral
Start date: 2007-05-07
Cubicin
Dosage: 350 mg, 1 in 1 d, intravenous (not otherwise specified)
Start date: 2007-05-11
Other drugs received by patient: Tazocin (Pip / Tazo); Humulin (Novolin 20 / 80); Primperan TAB; Enoxaparin Sodium; Ultra-Levure (Saccharomyces Boulardii); Citalopram Hydrobromide; Alfural (Alfuzosin Hydrochloride)
Adverse event in 82 year old female receiving Aricept (Donepezil)
Reported by a physician from Japan on 2007-07-24
Patient: 82 year old female, weighing 45.5 kg (100.1 pounds)
Adverse reactions / side effects: Rhabdomyolysis, Hypertension, Gastritis
Adverse event resulted in: hospitalization
Suspect drug(s):
Aricept (Donepezil)
Other drugs received by patient: Norvasc; Aldactone; Mucosta (Rebamipide); Bredinin (Mizoribine); Teprenone (Teprenone)
Adverse event in 58 year old male receiving Aricept (Donepezil)
Reported by a pharmacist from United Kingdom on 2007-07-24
Patient: 58 year old male
Adverse reactions / side effects: Vomiting, Nausea, Neutrophil Count Abnormal, Blood Test Abnormal
Suspect drug(s):
Aricept (Donepezil)
Other drugs received by patient: Citalopram Hydrobromide; Lansoprazole; Heloperidol (Haloperidol); Lactulose
Adverse event in 69 year old male receiving Aricept (Donepezil)
Reported by a health professional (non-physician/pharmacist) from Denmark on 2007-07-24
Patient: 69 year old male
Adverse reactions / side effects: Confusional State, Bradyarrhythmia, Fall, Cerebrovascular Accident, Altered State of Consciousness
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aricept (Donepezil)
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