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Amaryl (Glimepiride) - Adverse Event Reports - Life Threatening Events - Blood Bilirubin Increased

 



Index of reports > Cases resulting in life threatening events (7) > Cases with Blood Bilirubin Increased (2)

Below is the selection of adverse event reports related to Amaryl (Glimepiride) that includes cases resulting in life threatening events where reactions include blood bilirubin increased.

Adverse event in 87 year old female receiving Amaryl (Glimepiride)

Reported by a physician from Japan on 2007-07-23

Patient: 87 year old female, weighing 35.0 kg (77.0 pounds)

Adverse reactions / side effects: Blood Bilirubin Increased, Coagulopathy, Cholestasis, Coma, Hepatic Failure, Gastrointestinal Tube Insertion, Liver Disorder, Hepatic Encephalopathy, Subdural Haematoma, Malaise, Gamma-Glutamyltransferase Increased, Cholecystitis, Gallbladder Disorder, Prothrombin Time Ratio Increased, Alanine Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Tremor, Cholelithiasis, Anorexia, Aspartate Aminotransferase Increased, Gallbladder Polyp

Adverse event resulted in: death, life threatening event, hospitalization

Suspect drug(s):
Norvasc
    Dosage: 2.5 mg/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 1999-05-01
    End date: 2007-05-25

Amaryl
    Dosage: 1 mg/day
    Administration route: Oral
    Indication: Diabetes Mellitus
    Start date: 2007-04-01
    End date: 2007-05-17

Aspirin
    Dosage: 100 mg/day
    Administration route: Oral
    Indication: Angina Pectoris
    Start date: 2007-04-01
    End date: 2007-05-26

Diovan
    Dosage: 40 mg/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2006-06-14
    End date: 2007-05-23

Other drugs received by patient: Roxatidine Acetate HCL; Nateglinide; Triazolam; Lisinopril; Lisinopril



Adverse event in 87 year old female receiving Amaryl (Glimepiride)

Reported by a physician from Japan on 2007-06-11

Patient: 87 year old female

Adverse reactions / side effects: Blood Bilirubin Increased, Jaundice, Hepatic Encephalopathy, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Hepatic Failure, Tremor

Adverse event resulted in: life threatening event

Suspect drug(s):
Norvasc
    Dosage: 2.5 mg/day
    Administration route: Oral

Amaryl
    Dosage: 1 mg/day
    Administration route: Oral

Aspirin
    Dosage: 100 mg/day
    Administration route: Oral

Diovan
    Dosage: 40 mg/day
    Administration route: Oral
    Indication: Hypertension
    End date: 2007-05-23

Other drugs received by patient: Urso 250

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