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Index of reports
> Cases resulting in life threatening events (36)
> Cases with Hyperkalaemia (17)
Below is the selection of adverse event reports related to Aldactone (Spironolactone) that includes cases resulting in life threatening events where reactions include hyperkalaemia.
Adverse event in female receiving Aldactone (Spironolactone)
Reported by a physician from Japan on 2007-07-24
Patient: female, weighing 61.5 kg (135.3 pounds)
Adverse reactions / side effects: Hyperkalaemia, Bradyarrhythmia, Hypotension
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Administration route: Oral
Indication: Cardiac Failure
Start date: 2007-02-01
End date: 2007-06-27
Micardis
Indication: Hypertension
Start date: 2005-01-01
End date: 2007-06-27
Other drugs received by patient: Amaryl; Basen; Aspirin; Lasix; Artist; Frandol; Magnesium Oxide
Adverse event in 85 year old female receiving Aldactone (Spironolactone)
Reported by a pharmacist from Spain on 2007-07-06
Patient: 85 year old female, weighing 55.0 kg (121.0 pounds)
Adverse reactions / side effects: Syncope, Hyperkalaemia, Dizziness, Drug Interaction, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone (Spironolactone)
Other drugs received by patient possibly interacting with the suspect drug:
Olmesartan Medoxomil
Administration route: Oral
Indication: Hypertension
Start date: 2006-02-07
End date: 2007-05-15
Other drugs received by patient: Amitriptyline HCL; Omeprazole; Ferrous Sulfate; Folic Acid; Diltiazem
Adverse event in 82 year old female receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification from Japan on 2007-07-02
Patient: 82 year old female, weighing 56.0 kg (123.2 pounds)
Adverse reactions / side effects: Hyperkalaemia, Feeling Cold, Blood Pressure Inadequately Controlled, Sinus Arrest, Blood Creatinine Increased, White Blood Cell Count Increased, Renal Failure Acute, Ventricular Extrasystoles, Blood Urea Increased, Muscular Weakness, Blood Potassium Increased, Blood Bicarbonate Decreased, Computerised Tomogram Abnormal, Tremor, Haemodialysis, Haemoglobin Decreased, Anorexia, Renal Hypertension, Electrocardiogram Abnormal, Bradycardia, Gait Disturbance, Blood Pressure Decreased, Asthenia
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Dosage: 25 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 2002-11-18
End date: 2003-01-06
Diovan
Dosage: 80 mg, qd
Administration route: Oral
Indication: Hypertension
Start date: 2002-12-01
Diovan
Start date: 2002-12-12
End date: 2003-01-06
Landel
Dosage: 60 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 2001-02-27
End date: 2003-01-06
Landel
Dosage: 20 mg/day
Administration route: Oral
Start date: 2003-01-10
Odrik
Dosage: 2 mg/day
Administration route: Oral
Indication: Hypertension
Start date: 1997-11-06
End date: 2003-01-06
Pimenol
Dosage: 100 mg/day
Administration route: Oral
Indication: Ventricular Arrhythmia
Start date: 1997-11-06
End date: 2003-01-06
Salobel
Dosage: 100 mg/day
Administration route: Oral
Indication: Hyperuricaemia
Start date: 1997-02-25
End date: 2003-01-06
Spironolactone
Dosage: unk, unk
Administration route: Oral
Indication: Hypertension
Start date: 2002-11-01
Trandolapril
Administration route: Oral
Indication: Hypertension
Start date: 1982-01-01
Adverse event in 79 year old male receiving Aldactone (Spironolactone)
Reported by a pharmacist from Spain on 2007-05-18
Patient: 79 year old male
Adverse reactions / side effects: Hyperkalaemia
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Dosage: daily dose:100mg-freq:daily
Administration route: Oral
Norvasc
Dosage: daily dose:10mg-freq:daily
Administration route: Oral
Adverse event in 72 year old male receiving Aldactone (Spironolactone)
Reported by a pharmacist from Spain on 2007-05-03
Patient: 72 year old male
Adverse reactions / side effects: Hyperkalaemia, Atrioventricular Block Complete, Drug Interaction, Renal Failure Acute, Haemodialysis
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone (Spironolactone)
Other drugs received by patient possibly interacting with the suspect drug:
Furosemide
Dosage: daily dose:40mg-text:40 mg once daily
Administration route: Oral
Indication: Essential Hypertension
Manidon
Dosage: daily dose:240mg-text:240 mg daily
Administration route: Oral
Indication: Cardiac Disorder
Renitec
Dosage: daily dose:80mg-text:40 mg twice daily
Administration route: Oral
Indication: Essential Hypertension
Other drugs received by patient: Allopurinol; Atorvastatin Calcium
Adverse event in 59 year old male receiving Aldactone (Spironolactone)
Reported by a pharmacist from Spain on 2007-05-03
Patient: 59 year old male
Adverse reactions / side effects: Hyperkalaemia, Drug Interaction, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone (Spironolactone)
Other drugs received by patient possibly interacting with the suspect drug:
Antiinflammatory / Antirheumatic NON-Steroids
Dosage: freq:prn
Administration route: Oral
Indication: Arthropathy
Start date: 2007-03-11
End date: 2007-01-01
Seguril
Administration route: Oral
Start date: 2007-03-15
End date: 2007-03-22
Other drugs received by patient: Enalapril; Sustiva; Kaletra; Septra; Coropres; Uniket; Adiro; Omeprazole; Ziagen
Adverse event in 59 year old male receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification on 2007-04-30
Patient: 59 year old male
Adverse reactions / side effects: Hyperkalaemia, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Dosage: dose: unknown dosage
Administration route: Oral
Start date: 2007-03-15
End date: 2007-03-22
Nsaid's
Dosage: dose: unknown dosage
Administration route: Oral
Start date: 2007-03-11
End date: 2007-01-01
Seguril / 00032601 /
Dosage: dose: unknown dosage
Administration route: Oral
Start date: 2007-03-15
End date: 2007-03-22
Other drugs received by patient: Enalapril; Sustiva; Kaletra; Septrin; Coropres; Uniket; Adiro; Ziagen; Omeprazole
Adverse event in 72 year old male receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification on 2007-04-30
Patient: 72 year old male
Adverse reactions / side effects: Hyperkalaemia, Atrioventricular Block Complete, Haemodialysis, Renal Failure Acute
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Administration route: Oral
Indication: Essential Hypertension
Start date: 2006-07-04
End date: 2006-08-27
Manidon
Administration route: Oral
Indication: Cardiac Disorder
End date: 2006-08-27
Renitec / 00574901 /
Administration route: Oral
Indication: Essential Hypertension
End date: 2006-08-27
Seguril / 00032601 /
Administration route: Oral
Indication: Essential Hypertension
End date: 2006-08-27
Other drugs received by patient: Alopurinol; Zarator / 01326101 /
Adverse event in 82 year old male receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification on 2007-04-18
Patient: 82 year old male
Adverse reactions / side effects: Blood Urea Increased, Hyperkalaemia, Hyponatraemia
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
End date: 2006-03-28
Seguril / 00032601 /
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
End date: 2006-03-28
Adverse event in 95 year old female receiving Aldactone (Spironolactone)
Reported by a consumer/non-health professional from France on 2007-04-16
Patient: 95 year old female
Adverse reactions / side effects: OFF Label USE, Acute Pulmonary Oedema, Right Ventricular Failure, Cardiac Failure, Hyperkalaemia, Oedema Peripheral, Acidosis, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization
Suspect drug(s):
Aldactone
Administration route: Oral
Allopurinol
Administration route: Oral
Avandia
Administration route: Oral
Colchimax
Administration route: Oral
Fozitec
Administration route: Oral
Lasix
Administration route: Oral
Other drugs received by patient: Adancor; Kardegic; Cardensiel; Pariet; Stablon; Alprazolam; Zolpidem; Aluminum Hydroxide and Magnesium Trisilicate; Arestal
Adverse event in 67 year old male receiving Aldactone (Spironolactone)
Reported by a pharmacist from Spain on 2007-04-04
Patient: 67 year old male
Adverse reactions / side effects: Hyperkalaemia, Cardiac Arrest
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone (Spironolactone)
Other drugs received by patient: Sintrom; Digoxin; Cardura; Coropres; Metformin HCL
Adverse event in 86 year old female receiving Aldactone (Spironolactone)
Reported by a physician from Japan on 2007-03-16
Patient: 86 year old female
Adverse reactions / side effects: Hyperkalaemia
Adverse event resulted in: death, life threatening event
Suspect drug(s):
Aldactone
Administration route: Oral
Indication: Cardiac Failure
Start date: 2004-04-07
End date: 2007-02-07
Cozaar
Administration route: Oral
Indication: Hypertension
Start date: 2006-08-03
End date: 2007-02-07
Other drugs received by patient: Lasix; Takepron; Lendormin; Zolpidem Tartrate; Pursennid; Argamate Jelly
Adverse event in 86 year old female receiving Aldactone (Spironolactone)
Reported by a physician from Japan on 2007-03-09
Patient: 86 year old female
Adverse reactions / side effects: Hyperkalaemia
Adverse event resulted in: death, life threatening event
Suspect drug(s):
Aldactone
Administration route: Oral
Indication: Cardiac Failure
Start date: 2004-04-07
End date: 2007-02-07
Cozaar
Administration route: Oral
Indication: Hypertension
Start date: 2006-08-03
End date: 2007-02-07
Other drugs received by patient: Pursennid; Argamate Jelly; Lasix; Takepron; Lendormin; Zolpidem Tartrate
Adverse event in female receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification from Japan on 2007-02-23
Patient: female, weighing 55.3 kg (121.7 pounds)
Adverse reactions / side effects: Metabolic Acidosis, Hyperkalaemia, Hypoglycaemia, Cardiac Arrest, Electromechanical Dissociation, Haemodialysis
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Dosage: daily dose:25mg
Administration route: Oral
Indication: Diabetic Nephropathy
Blopress
Administration route: Oral
End date: 2006-09-01
Other drugs received by patient: Amaryl; Aspirin; Alfarol; Calcium Lactate; Euglucon; Basen; Melbin; Humulin R
Adverse event in female receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification from Japan on 2007-02-13
Patient: female, weighing 55.3 kg (121.7 pounds)
Adverse reactions / side effects: Metabolic Acidosis, Hyperkalaemia, Cardiac Arrest
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Dosage: daily dose:25mg
Administration route: Oral
Indication: Diabetic Nephropathy
Blopress
Administration route: Oral
End date: 2006-09-01
Other drugs received by patient: Amaryl; Aspirin; Alfarol; Calcium Lactate
Adverse event in 88 year old female receiving Aldactone (Spironolactone)
Reported by a pharmacist from Spain on 2007-02-08
Patient: 88 year old female
Adverse reactions / side effects: Blood Urea Increased, Hyperkalaemia, Diarrhoea
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Enalapril Maleate
Tavanic
Administration route: Oral
Indication: Upper Respiratory Tract Infection
Start date: 2006-12-15
End date: 2006-12-20
Adverse event in female receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification from Japan on 2007-01-30
Patient: female, weighing 55.3 kg (121.7 pounds)
Adverse reactions / side effects: Metabolic Acidosis, Hyperkalaemia, Cardiac Arrest
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone
Dosage: daily dose:25mg
Administration route: Oral
Indication: Diabetic Nephropathy
Blopress
Administration route: Oral
End date: 2006-09-01
Other drugs received by patient: Amaryl; Aspirin; Alfarol; Calcium Lactate
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