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This is an index of reports of adverse events (side effects, adverse reactions, etc.) related to Aldactone (Spironolactone). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the side effect / adverse reaction. Or scroll down to view a sample of recent reports further on this page.
Our database includes reports from Jan 2007 to Dec 2007. The information is not vetted and should not be cosidered as verified clinical evidence.
All cases (253)
Cases resulting in a serious event (253)
Cases resulting in death (25)
Cases resulting in life threatening events (36)
Cases resulting in hospitalization (165)
Cases resulting in disability (11)
Cases resulting in other serious reactions (86)
Below is a sample of reports where side effects / adverse reactions may be related to Aldactone (Spironolactone). For a complete list and/or a specific selection of reports, please use the links in the index above.
Adverse event in female receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification from Brazil on 2007-10-30
Patient: female
Adverse reactions / side effects: Drug Ineffective, Impaired Work Ability, Ill-Defined Disorder, Palpitations, Diarrhoea, Pulmonary Oedema, Oedema, Arterial Occlusive Disease, Depression, Myocardial Infarction, Blood Glucose Increased, Haematoma
Adverse event resulted in: disablity
Suspect drug(s):
Olmesartan Medoxomil
Dosage: 20 mg (20 mg,qd),per oral
Administration route: Oral
Indication: Hypertension
Start date: 2004-01-01
Diabinese
Dosage: 500 mg (250 mg,bid),per oral
Administration route: Oral
Indication: Diabetes Mellitus
Start date: 1996-01-01
End date: 2004-11-30
Norvasc
Dosage: 5 mg (5 mg,qd),per oral
Administration route: Oral
Indication: Drug USE FOR Unknown Indication
Start date: 2004-01-01
End date: 2006-01-01
Caduet
Dosage: 10/5 mg (bid),per oral
Administration route: Oral
Indication: Hypertension
Start date: 2004-01-01
Aldactone
Dosage: (qd), per oral
Administration route: Oral
Indication: Hypertension
Start date: 2004-01-01
Coristina D (Acetysalicylic Acid, Cafffeine, Phenylephrine Hydrochlori
Indication: Drug USE FOR Unknown Indication
Other drugs received by patient: Insulin (Insulin) (-Injection) (Insulin)
Adverse event in receiving Aldactone (Spironolactone)
Reported by a consumer/non-health professional from France on 2007-10-29
Patient:
Adverse reactions / side effects: Blood Urea Increased, Overdose, Drug Interaction, Blood Creatinine Increased, Renal Failure Acute
Adverse event resulted in: hospitalization
Suspect drug(s):
Ramipril
Dosage: 2.5 mg, bid
Administration route: Oral
End date: 2007-09-08
Lasix
Dosage: 40 mg, bid
Administration route: Oral
End date: 2007-09-08
Aldactone
Dosage: 250 mg, qd
Administration route: Oral
End date: 2007-09-08
Other drugs received by patient: Ditropan / 00538901 /; Escitalopram; Ogast; Previscan / 00789001 /; Lyrica; Havlane; Novomix / 01475801 /
Adverse event in female receiving Aldactone (Spironolactone)
Reported by a consumer/non-health professional from Brazil on 2007-10-26
Patient: female
Adverse reactions / side effects: Syncope, Dyspnoea, Injection Site Haematoma, Coagulopathy, Oedema, Arterial Occlusive Disease, Pulmonary Oedema, Depression, Myocardial Infarction, Blood Glucose Increased
Adverse event resulted in: life threatening event, hospitalization, disablity
Suspect drug(s):
Diabinese
Administration route: Oral
Indication: Diabetes Mellitus
Start date: 1996-01-01
End date: 2004-11-30
Norvasc
Administration route: Oral
Start date: 2004-01-01
End date: 2006-01-01
Caduet
Dosage: text:10mg/5mg;20mg/10mg
Administration route: Oral
Indication: Hypertension
Aldactone
Administration route: Oral
Indication: Hypertension
Olmetec
Administration route: Oral
Indication: Hypertension
Coristina D
Administration route: Oral
Indication: Influenza
Insulin
Indication: Diabetes Mellitus
Start date: 2004-11-01
Novonorm
Adverse event in 71 year old male receiving Aldactone (Spironolactone)
Reported by a physician from France on 2007-10-24
Patient: 71 year old male, weighing 58.0 kg (127.6 pounds)
Adverse reactions / side effects: Toxic Epidermal Necrolysis
Adverse event resulted in: death
Suspect drug(s):
Lasix
Administration route: Oral
Start date: 2007-01-27
End date: 2007-02-11
Claforan
Start date: 2007-02-05
End date: 2007-02-09
Aldactone
Administration route: Oral
Start date: 2007-01-27
End date: 2007-02-11
Efferalgan / 00020001 /
Administration route: Oral
Start date: 2007-01-31
End date: 2007-02-09
Ciflox / 00697201 /
Administration route: Oral
Start date: 2007-02-09
End date: 2007-02-10
Inipomp / 01263201 /
Administration route: Oral
Start date: 2007-02-06
End date: 2007-02-11
Other drugs received by patient: Solupred / 00016201 /; Aerius / 01398501 /; Atarax / 00058402 /; Propranolol Hydrochloride; Mycostatin
Adverse event in male receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification from United States on 2007-10-24
Patient: male, weighing 95.0 kg (209.0 pounds)
Adverse reactions / side effects: Renal Failure, Diabetes Mellitus, Hypotension, Cardiac Failure Congestive
Adverse event resulted in: hospitalization
Suspect drug(s):
Bibr 1048 (Dabigatran Etexilate) (Blind)
Administration route: Oral
Indication: Cerebrovascular Accident Prophylaxis
Bibr 1048 (Dabigatran Etexilate) (Blind)
Indication: Thrombosis Prophylaxis
Lasix
Administration route: Oral
Indication: Hypertension
Lasix
Indication: Cardiac Failure Congestive
Vasotec
Administration route: Oral
Indication: Hypertension
Vasotec
Indication: Cardiac Failure Congestive
Digoxin
Administration route: Oral
Indication: Ischaemic Cardiomyopathy
Aldactone
Administration route: Oral
Indication: Hypertension
Other drugs received by patient: Levemir; Digitek
Adverse event in male receiving Aldactone (Spironolactone)
Reported by a physician from United States on 2007-10-23
Patient: male
Adverse reactions / side effects: Renal Failure, Hypotension, Cardiac Failure Congestive
Adverse event resulted in: hospitalization
Suspect drug(s):
Aldactone
Dosage: daily dose:25mg-freq:frequency: 25mg, qod
Administration route: Oral
Indication: Hypertension
Blinded Spironolactone
Administration route: Oral
Indication: Prophylaxis
Blinded Spironolactone
Indication: Embolism
Lasix
Dosage: daily dose:40mg
Administration route: Oral
Indication: Hypertension
Lasix
Indication: Cardiac Failure Congestive
Vasotec
Dosage: daily dose:10mg
Administration route: Oral
Indication: Hypertension
Vasotec
Indication: Cardiac Failure Congestive
Digoxin
Dosage: daily dose:.125mg
Administration route: Oral
Indication: Ischaemic Cardiomyopathy
Adverse event in male receiving Aldactone (Spironolactone)
Reported by a lawyer from Norway on 2007-10-23
Patient: male
Adverse reactions / side effects: Dyspepsia, Nausea, Dizziness, Visual Acuity Reduced, Erectile Dysfunction, Gynaecomastia, Meniere's Disease
Suspect drug(s):
Aldactone
Indication: Hypertension
Start date: 1997-01-01
End date: 1999-01-01
Aldactone
Indication: Hyperaldosteronism
Adverse event in 52 year old male receiving Aldactone (Spironolactone)
Reported by a health professional (non-physician/pharmacist) from France on 2007-10-23
Patient: 52 year old male
Adverse reactions / side effects: Phlebitis, Pulmonary Embolism
Adverse event resulted in: hospitalization
Suspect drug(s):
Aldactone
Administration route: Oral
Indication: Nephrotic Syndrome
Thalidomide
Administration route: Oral
Indication: Multiple Myeloma
Lasix
Administration route: Oral
Indication: Nephrotic Syndrome
Triatec
Administration route: Oral
Indication: Nephrotic Syndrome
Other drugs received by patient: Alkeran; Dexamethasone
Adverse event in 71 year old male receiving Aldactone (Spironolactone)
Reported by a physician from France on 2007-10-19
Patient: 71 year old male, weighing 58.0 kg (127.6 pounds)
Adverse reactions / side effects: Toxic Epidermal Necrolysis
Adverse event resulted in: death
Suspect drug(s):
Claforan
Start date: 2007-02-05
End date: 2007-02-09
Lasix
Administration route: Oral
Start date: 2007-01-27
End date: 2007-02-11
Aldactone
Administration route: Oral
Start date: 2007-01-27
End date: 2007-02-11
Efferalgan / 00020001 /
Administration route: Oral
Start date: 2007-01-31
End date: 2007-02-09
Ciflox / 00697201 /
Administration route: Oral
Start date: 2007-02-09
End date: 2007-02-10
Inipomp / 01263201 /
Administration route: Oral
Start date: 2007-02-06
End date: 2007-02-11
Other drugs received by patient: Solupred / 00016201 /; Aerius / 01398501 /; Atarax / 00058402 /; Propranolol Hydrochloride; Mycostatin
Adverse event in male receiving Aldactone (Spironolactone)
Reported by a physician from Australia on 2007-10-19
Patient: male, weighing 130.0 kg (286.0 pounds)
Adverse reactions / side effects: Pulmonary Hypertension, Dyspnoea, Pneumonia, Anaemia, Encephalopathy, Tricuspid Valve Incompetence, Surgery, Cardiac Failure, Mitral Valve Incompetence, Oedema Peripheral, Sleep Apnoea Syndrome, Alcohol Problem
Suspect drug(s):
Aldactone
Administration route: Oral
Indication: Oedema
Lipitor
Dosage: daily dose:20mg
Administration route: Oral
Indication: Hyperlipidaemia
Other drugs received by patient: Atacand; Lasix; Dilatrend; Endep; Warfarin Sodium; Zyloprim; Diaformin
Adverse event in 65 year old male receiving Aldactone (Spironolactone)
Reported by a physician from United States on 2007-10-18
Patient: 65 year old male
Adverse reactions / side effects: Renal Failure, Hypotension
Adverse event resulted in: hospitalization
Suspect drug(s):
Lasix
Administration route: Oral
Indication: Hypertension
Lasix
Administration route: Oral
Aldactone
Administration route: Oral
Indication: Hypertension
Antithrombotic Agents
Dosage: dose: unk
Antithrombotic Agents
Dosage: dose: unk
Vasotec / 00935901 /
Administration route: Oral
Indication: Hypertension
Vasotec / 00935901 /
Administration route: Oral
Digoxin
Administration route: Oral
Adverse event in receiving Aldactone (Spironolactone)
Reported by a consumer/non-health professional from France on 2007-10-17
Patient:
Adverse reactions / side effects: Hypotension, Rectal Haemorrhage, Gastric Ulcer
Adverse event resulted in: hospitalization
Suspect drug(s):
Altace
Dosage: 1 u, qd
Administration route: Oral
Indication: Hypertension
Lasix
Dosage: 40 mg, qd
Administration route: Oral
Indication: Cardiac Failure
Previscan / 00789001 /
Dosage: 25 mg, qd
Administration route: Oral
Indication: Thrombosis
End date: 2006-10-13
Previscan / 00789001 /
Start date: 2006-10-15
Aldactone
Dosage: 1 u film-coated tablet
Administration route: Oral
Indication: Cardiac Failure
Elisor
Dosage: 1 u tablet,qd
Administration route: Oral
Indication: Hypercholesterolaemia
Adverse event in 71 year old male receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification on 2007-10-17
Patient: 71 year old male
Adverse reactions / side effects: Drug Interaction, Renal Failure Acute
Adverse event resulted in: hospitalization
Suspect drug(s):
Ramipril
Administration route: Oral
End date: 2007-09-08
Lasix
Administration route: Oral
End date: 2007-09-08
Aldactone
Administration route: Oral
End date: 2007-09-08
Other drugs received by patient: Ditropan; Escitalopram; Ogast; Previscan / 00789001 /; Lyrica; Havlane; Novomix / 01475801 /
Adverse event in male receiving Aldactone (Spironolactone)
Reported by a health professional (non-physician/pharmacist) from France on 2007-10-16
Patient: male
Adverse reactions / side effects: Malaise, Hyperkalaemia, Bundle Branch Block
Adverse event resulted in: hospitalization
Suspect drug(s):
Atacand
Administration route: Oral
Aldactone
Administration route: Oral
End date: 2006-10-17
Lasix
Administration route: Oral
Other drugs received by patient: Tahor; Metformin
Adverse event in female receiving Aldactone (Spironolactone)
Reported by a consumer/non-health professional from United States on 2007-10-15
Patient: female, weighing 61.4 kg (135.0 pounds)
Adverse reactions / side effects: Bone Neoplasm Malignant, Renal Failure, Cardiac Failure, Hypotension, Oedema Peripheral, Tachycardia
Adverse event resulted in: death
Suspect drug(s):
Aldactone
Indication: Cardiac Failure Congestive
Start date: 2006-11-01
End date: 2007-03-01
Aldactone
Indication: Hypertension
Metoprolol
Lasix
Other drugs received by patient: Fentanyl
Adverse event in 70 year old male receiving Aldactone (Spironolactone)
Reported by a physician from Japan on 2007-10-12
Patient: 70 year old male
Adverse reactions / side effects: Interstitial Lung Disease
Adverse event resulted in: hospitalization
Suspect drug(s):
Lansoprazole
Administration route: Oral
Start date: 2007-05-11
End date: 2007-06-13
Lasix
Administration route: Oral
Indication: Cardiac Failure
Start date: 2007-05-11
End date: 2007-06-13
Artist
Administration route: Oral
Indication: Cardiac Failure
Start date: 2007-05-15
End date: 2007-06-13
Renivace
Administration route: Oral
Indication: Cardiac Failure
Start date: 2007-05-06
End date: 2007-06-13
Amlodipine
Administration route: Oral
Indication: Cardiac Failure
Start date: 2007-05-09
End date: 2007-06-13
Magmit
Administration route: Oral
Indication: Constipation
Start date: 2007-05-09
End date: 2007-06-13
Aldactone
Administration route: Oral
Indication: Cardiac Failure
Start date: 2007-05-14
End date: 2007-06-13
Other drugs received by patient: Aspirin; Ticlopidine HCL
Adverse event in male receiving Aldactone (Spironolactone)
Reported by a physician from United Kingdom on 2007-10-12
Patient: male
Adverse reactions / side effects: Blood Testosterone Decreased, Erectile Dysfunction
Suspect drug(s):
Aldactone (Spironolactone)
Adverse event in 62 year old female receiving Aldactone (Spironolactone)
Reported by a physician from Japan on 2007-10-12
Patient: 62 year old female
Adverse reactions / side effects: Pulmonary Embolism, Deep Vein Thrombosis
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Aldactone (Spironolactone)
Other drugs received by patient: NU Lotan; Mercazole
Adverse event in 72 year old male receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification on 2007-10-11
Patient: 72 year old male
Adverse reactions / side effects: Malaise, Hyperkalaemia, Bundle Branch Block
Adverse event resulted in: hospitalization
Suspect drug(s):
Lasix
Administration route: Oral
Aldactone
Administration route: Oral
End date: 2006-10-17
Atacand
Administration route: Oral
Other drugs received by patient: Tahor; Metformin HCL; Amlor
Adverse event in 46 year old female receiving Aldactone (Spironolactone)
Reported by a pharmacist from Japan on 2007-10-06
Patient: 46 year old female
Adverse reactions / side effects: Breast Swelling, Metrorrhagia
Suspect drug(s):
Aldactone (Spironolactone)
Other drugs received by patient: Gleevec; Lasix; Drug, Unspecified
Adverse event in receiving Aldactone (Spironolactone)
Reported by a consumer/non-health professional from France on 2007-10-05
Patient:
Adverse reactions / side effects: Phlebitis, Pulmonary Embolism, Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Suspect drug(s):
Altace
Dosage: 1.25 mg, qd
Administration route: Oral
Indication: Nephrotic Syndrome
Lasix
Dosage: unk, qd
Administration route: Oral
Indication: Nephrotic Syndrome
Thalidomide
Dosage: 200 mg, qd
Administration route: Oral
Indication: Multiple Myeloma
Aldactone
Dosage: 75 mg, qd
Administration route: Oral
Indication: Nephrotic Syndrome
Other drugs received by patient: Alkeran; Dexamethasone 0.5mg TAB; Previscan / 00789001 /
Adverse event in 53 year old male receiving Aldactone (Spironolactone)
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-10-04
Patient: 53 year old male
Adverse reactions / side effects: Hepatic Encephalopathy, Infection
Adverse event resulted in: hospitalization
Suspect drug(s):
Avlocardyl LP
Administration route: Oral
Actiskenan
Dosage: not provided
Administration route: Oral
Start date: 2006-07-05
End date: 2006-07-10
Stablon
Administration route: Oral
Indication: Depression
Aldactone
Administration route: Oral
Pentoxifylline
Administration route: Oral
Indication: Cirrhosis Alcoholic
Start date: 2006-01-06
End date: 2006-07-13
Dafalgan Codeine
Administration route: Oral
Start date: 2006-07-05
End date: 2006-07-10
Other drugs received by patient: Clamoxyl; Lantus; Duphalac; Vitamin B1 and B6; Novorapid
Adverse event in 58 year old male receiving Aldactone (Spironolactone)
Reported by a individual with unspecified qualification on 2007-10-04
Patient: 58 year old male
Adverse reactions / side effects: Rectal Haemorrhage
Adverse event resulted in: hospitalization
Suspect drug(s):
Ramipril
Administration route: Oral
Lasix
Administration route: Oral
Indication: Cardiac Failure
Previscan / 00789001 /
Administration route: Oral
Indication: Thrombosis
End date: 2006-10-13
Aldactone
Administration route: Oral
Indication: Cardiac Failure
Elisor
Administration route: Oral
Adverse event in 57 year old male receiving Aldactone (Spironolactone)
Reported by a pharmacist from Japan on 2007-10-02
Patient: 57 year old male, weighing 59.0 kg (129.8 pounds)
Adverse reactions / side effects: White Blood Cell Count Decreased, Dyspnoea, Pericardial Effusion, Haemoglobin Decreased, Haematocrit Decreased, Thrombocytopenic Purpura, Platelet Count Decreased, Haemorrhagic Diathesis, Rash Maculo-Papular
Adverse event resulted in: life threatening event
Suspect drug(s):
Lasix
Dosage: 20 mg/day
Administration route: Oral
Indication: Cardiac Failure Congestive
Start date: 2007-06-12
End date: 2007-07-13
Aldactone
Dosage: 25 mg/day
Administration route: Oral
Indication: Cardiac Failure Congestive
Start date: 2007-06-27
End date: 2007-07-20
Tenormin
Dosage: 25 mg/day
Administration route: Oral
Indication: Atrial Fibrillation
Start date: 2004-04-01
End date: 2007-07-20
Micardis
Dosage: 20 mg/day
Administration route: Oral
Indication: Cardiac Failure Congestive
Start date: 2004-04-01
End date: 2007-07-20
Warfarin Sodium
Dosage: 3 mg/day
Administration route: Oral
Indication: Atrial Fibrillation
Start date: 2007-06-07
End date: 2007-07-09
Propylthiouracil
Dosage: 300 mg/day
Administration route: Oral
Start date: 1987-01-01
End date: 2007-07-12
Propylthiouracil
Dosage: 200 mg/day
Administration route: Oral
Start date: 2007-07-13
End date: 2007-07-20
Propylthiouracil
Dosage: 300 mg/day
Administration route: Oral
Start date: 2007-08-03
Mucosta
Dosage: 300 mg/day
Administration route: Oral
Indication: Gastric Mucosal Lesion
Start date: 2007-05-18
End date: 2007-07-13
Sigmart
Dosage: 15 mg/day
Administration route: Oral
Indication: Angina Pectoris
Start date: 2004-04-01
End date: 2007-07-13
Bepricor
Dosage: 150 mg/day
Administration route: Oral
Indication: Atrial Fibrillation
Start date: 2007-07-02
End date: 2007-07-20
Nitroderm
Dosage: 1 patch/day
Indication: Angina Pectoris
Start date: 2007-07-13
Amlodipine Besylate
Indication: Angina Pectoris
Start date: 2004-04-01
Aspirin
Dosage: 100mg
Administration route: Oral
End date: 2007-07-12
Other drugs received by patient: Unasyn; Gentacin
Adverse event in 59 year old female receiving Aldactone (Spironolactone)
Reported by a physician from Japan on 2007-10-01
Patient: 59 year old female
Adverse reactions / side effects: Pancreatitis Acute
Suspect drug(s):
Aldactone
Administration route: Oral
Indication: Cardiac Failure
Furosemide
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