Actos (Pioglitazone) - Adverse Event Reports - Serious Event - Weight Increased

Adverse event in 63 year old male receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from United States on 2007-10-31

Patient: 63 year old male, weighing 102.1 kg (224.5 pounds)

Adverse reactions / side effects: Weight Increased, Increased Appetite, Lethargy

Suspect drug(s):
Actos (Pioglitazone)

Adverse event in 61 year old female receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from Netherlands on 2007-10-30

Patient: 61 year old female

Adverse reactions / side effects: Weight Increased

Adverse event resulted in: death

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Novomin (Dimenhydrinate); Valproate Sodium; Lasix; Thyrax (Levothyroxine Sodium); Cozaar

Adverse event in 64 year old female receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from United Kingdom on 2007-10-19

Patient: 64 year old female

Adverse reactions / side effects: Weight Increased, Joint Swelling, Cardiac Failure, Oedema Peripheral

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Insulin; Metformin HCL

Adverse event in 63 year old female receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from United Kingdom on 2007-10-19

Patient: 63 year old female

Adverse reactions / side effects: Weight Increased, Dyspnoea, Hepatomegaly, Cardiac Failure, Oedema Peripheral, Rales, Fluid Retention, Ascites

Adverse event resulted in: disablity

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Insulin Humalog MIX 50 (Insulin Lispro); Levemir (Insulin Detemir)

Adverse event in 58 year old female receiving Actos (Pioglitazone)

Reported by a physician from United States on 2007-10-18

Patient: 58 year old female, weighing 144.2 kg (317.3 pounds)

Adverse reactions / side effects: Weight Decreased, Drug Ineffective, Hypoglycaemia, Hepatic Failure, Headache, Hyperhidrosis, Cardiac Disorder, Herpes Zoster, Weight Increased, Blood Uric Acid Decreased, Kidney Infection, Transient Ischaemic Attack, Diabetes Mellitus Inadequate Control, Cardiac Failure Congestive, Renal Haemorrhage, Cellulitis, Nausea, Rash, Tremor, Renal Failure, Arthralgia, Diabetic Neuropathy, Swelling, Asthenia, Angiopathy, Influenza Like Illness

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos
    Dosage: see image
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    End date: 2006-01-01

Actos
    Dosage: see image
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    Start date: 2001-01-01

Actos
    Dosage: see image
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    Start date: 2002-01-01

Actos
    Dosage: see image
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    Start date: 2006-01-01

Actos

Glyburide
    Dosage: 5 mg, 3 in 1 d, per oral
    Administration route: Oral
    Indication: Diabetes Mellitus
    Start date: 2001-01-01

Glipizide
    Dosage: 5 mg, 3 in 1 d, per oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    Start date: 2004-01-01

Lyrica
    Dosage: per oral
    Administration route: Oral
    Indication: Diabetic Neuropathy
    Start date: 2004-01-01
    End date: 2004-01-01

Byetta
    Dosage: 5 mcg, 2 in 1 d, subcutaneous
    Indication: Type 2 Diabetes Mellitus
    Start date: 2007-07-01

Byetta
    Dosage: 5 mcg, 2 in 1 d, subcutaneous
    Indication: Weight Decreased
    Start date: 2007-07-01

Levaquin
    Dosage: 750 mg, 1 in 1 d, intravenous
    Indication: Kidney Infection
    Start date: 2007-01-01
    End date: 2007-01-01

Other drugs received by patient: Ibuprofen; Atacand (Candesartan Cilexetil) (16 Milligram); Lasix (Furosemide) (20 Milligram); Demadex; Nitrostat

Adverse event in 63 year old female receiving Actos (Pioglitazone)

Reported by a consumer/non-health professional from United States on 2007-10-16

Patient: 63 year old female, weighing 104.3 kg (229.5 pounds)

Adverse reactions / side effects: Weight Increased, Abdominal Infection, Accident, Blood Glucose Decreased, Malaise, Abdominal Strangulated Hernia, Dizziness, Blood Glucose Increased, Sudden Onset of Sleep

Suspect drug(s):
Actos
    Dosage: 30 mg, 1 in 1 d, per oral; 30 mg, 1/2 tablet, 1 in 1 d, per oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    Start date: 2006-06-01
    End date: 2007-05-01

Actos
    Dosage: 30 mg, 1 in 1 d, per oral; 30 mg, 1/2 tablet, 1 in 1 d, per oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus
    Start date: 2007-05-01
    End date: 2007-06-13

Other drugs received by patient: Oxytrol; Detrol

Adverse event in 57 year old male receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from United States on 2007-10-12

Patient: 57 year old male, weighing 113.4 kg (249.5 pounds)

Adverse reactions / side effects: Weight Increased, Fatigue, Oedema Peripheral, Swelling

Adverse event resulted in: life threatening event, disablity

Suspect drug(s):
Actos (Pioglitazone)

Adverse event in 75 year old female receiving Actos (Pioglitazone)

Reported by a consumer/non-health professional from United States on 2007-10-04

Patient: 75 year old female, weighing 77.1 kg (169.6 pounds)

Adverse reactions / side effects: Weight Increased, Weight Decreased, Fracture, Pain, Tibia Fracture, Stress Fracture, Fluid Retention

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Hydrochlorothiazide; Altace; Lipitor

Adverse event in 75 year old female receiving Actos (Pioglitazone)

Reported by a consumer/non-health professional from United States on 2007-10-01

Patient: 75 year old female, weighing 88.5 kg (194.6 pounds)

Adverse reactions / side effects: Weight Increased, Dyspnoea, Oedema Peripheral, Cardiac Failure Congestive

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Furosemide; Diltiazem; Labetalol HCL; Quinapril HCL; Spironolactone; Metformin HCL; Lyrica; Atacand

Adverse event in 65 year old male receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from Japan on 2007-07-25

Patient: 65 year old male

Adverse reactions / side effects: Weight Increased, Cardiac Failure, Pleural Effusion, Condition Aggravated, Fluid Retention, Pericardial Effusion, Urine Output Increased

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Basen (Voglibose); Lasix; Aldactone; Digoxin; Micardis; Biofermin (Lactobacillus Acidophilus, Bacillus Subtilis, Streptococcus; Tenormin; Disopyramide; Tamsulosin HCL

Adverse event in 46 year old male receiving Actos (Pioglitazone)

Reported by a physician from United States on 2007-07-25

Patient: 46 year old male, weighing 99.8 kg (219.5 pounds)

Adverse reactions / side effects: Intervertebral Disc Protrusion, Nerve Injury, Weight Increased, Bone Disorder, Back Injury, Diabetes Mellitus Inadequate Control

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos
    Dosage: 30 mg, 1 in 1 d, per oral; 45 mg, 1 in 1 d, per oral
    Administration route: Oral
    Indication: Diabetes Mellitus
    End date: 2006-02-01

Actos
    Dosage: 30 mg, 1 in 1 d, per oral; 45 mg, 1 in 1 d, per oral
    Administration route: Oral
    Indication: Diabetes Mellitus
    Start date: 2006-02-01

Other drugs received by patient: Tricor; Crestor; Prevacid; Novolog MIX 70 / 30; Effexor

Adverse event in 60 year old female receiving Actos (Pioglitazone)

Reported by a consumer/non-health professional from United States on 2007-07-25

Patient: 60 year old female, weighing 90.7 kg (199.6 pounds)

Adverse reactions / side effects: Weight Increased, Pain in Extremity, Oedema Peripheral, Gait Disturbance

Suspect drug(s):
Avandia
    Indication: Diabetes Mellitus
    Start date: 2007-01-01

Actos
    Indication: Diabetes Mellitus
    Start date: 2007-01-01

Adverse event in 60 year old male receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from Japan on 2007-07-06

Patient: 60 year old male

Adverse reactions / side effects: Weight Increased, Dyspnoea, Glycosylated Haemoglobin Increased, Supraventricular Extrasystoles, Oedema Peripheral, Rhinorrhoea, Pulmonary Oedema

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Blopress (Candesartan Cilexetil); Glufast (Mitiglinide Calcium Hydrate); Amaryl; Livalo (Itavastatin Calcium); Norvasc; PL (Caffeine, Salicylamide, Paracetamol, Promethazine Methylene Disali; Solantal (Tiaramide Hydrochloride); Flomox (Cefcapene Pivoxil Hydrochloride); Marzulene S (Levoglutamide, Sodium Gualenate); Codeine Phosphate; Onon (Pranlukast); Zyrtec

Adverse event in 71 year old female receiving Actos (Pioglitazone)

Reported by a consumer/non-health professional from United States on 2007-07-03

Patient: 71 year old female, weighing 137.6 kg (302.7 pounds)

Adverse reactions / side effects: Protein Urine Present, Spinal Fracture, Colitis Ulcerative, Drug Ineffective, Pain, Rash, Pyrexia, Cushing's Syndrome, Herpes Zoster, Rheumatoid Arthritis, Weight Increased, Alopecia, Blood Glucose Increased, Crying, RIB Fracture, Inflammation

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos
    Dosage: per oral
    Administration route: Oral
    Start date: 2001-01-01
    End date: 2006-01-01

Humalog
    Dosage: see image
    Indication: Diabetes Mellitus
    Start date: 2001-01-01

Prednisone TAB
    Dosage: 16-20 mg, 1 in 1 d
    Indication: Inflammation
    Start date: 2001-01-01

Prednisone TAB
    Dosage: 16-20 mg, 1 in 1 d
    Indication: Rheumatoid Arthritis
    Start date: 2001-01-01

Enbrel
    Start date: 2002-01-01
    End date: 2005-01-01

Mercaptopurine
    Dosage: per rectal

Prednisone TAB
    Indication: Colitis Ulcerative

Humulin R
    Dosage: 100u/ml, 10ml x 1 vial amf

Other drugs received by patient: Asacol; Cozaar; Lantus; Soma; Atarax; Neurontin; Acetaminophen; Q10 (Ubidecarenone); Folic Acid; Unknown Diuretics (Diuretics); Robaxin; Glucophage; Actonel

Adverse event in 62 year old female receiving Actos (Pioglitazone)

Reported by a consumer/non-health professional from United States on 2007-06-19

Patient: 62 year old female, weighing 144.2 kg (317.3 pounds)

Adverse reactions / side effects: Cardiac Failure Chronic, Hemiparesis, Rash, Hyperhidrosis, Tremor, Weight Increased, Blood Glucose Decreased, Arthralgia, Diabetic Neuropathy, Oedema Peripheral, Blood Glucose Fluctuation, Transient Ischaemic Attack, Asthenia

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos
    Dosage: see image
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2001-01-01

Glyburide
    Dosage: 5 mg, 3 in 1 d, per oral
    Administration route: Oral
    Indication: Diabetes Mellitus
    Start date: 2001-01-01

Glipizide
    Dosage: 5 mg, 3 in 1 d, per oral
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2004-01-01

Other drugs received by patient: Ibuprofen (Ibuprofen) (200 Milligram); Atacand (Candesartan Cilexetil) (16 Milligram); Lasix (Furosemide) (20 Milligram); Demadex; Nitrostat; Lyrica

Adverse event in 71 year old female receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from United States on 2007-05-29

Patient: 71 year old female, weighing 137.6 kg (302.7 pounds)

Adverse reactions / side effects: Pituitary-Dependent Cushing's Syndrome, Colitis Ulcerative, Drug Ineffective, Osteoporosis, Pain, Pyrexia, Somnolence, Herpes Zoster, Wound Secretion, Rheumatoid Arthritis, Weight Increased, Dyspepsia, Oedema Peripheral, Wound Drainage, Blood Glucose Increased, RIB Fracture, Protein Urine Present, Back Pain, Renal Disorder, Spinal Fracture, Rash, Alopecia, Asthenia, Inflammation

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos
    Dosage: per oral
    Administration route: Oral
    Start date: 2001-01-01
    End date: 2006-01-01

Humalog
    Dosage: see image
    Indication: Diabetes Mellitus
    Start date: 2001-01-01

Prednisone TAB
    Dosage: 16-20 mg, 1 in 1 d, unknown
    Indication: Inflammation
    Start date: 2001-01-01

Prednisone TAB
    Dosage: 16-20 mg, 1 in 1 d, unknown
    Indication: Rheumatoid Arthritis
    Start date: 2001-01-01

Enbrel
    Start date: 2002-01-01
    End date: 2005-01-01

Mercaptopurine

Prednisone TAB
    Dosage: per rectal
    Indication: Colitis Ulcerative

Humulin R
    Dosage: 100u/ml, 10ml x 1 vial amf, unknown

Other drugs received by patient: Asacol; Cozaar; Lantus; Soma; Atarax; Neurontin; Tylenol; Q10 (Ubidecarenone); Folic Acid; Unknown Diuretics (Diuretics); Robaxin; Glucophage; Actonel

Adverse event in 73 year old male receiving Actos (Pioglitazone)

Reported by a physician from United States on 2007-05-29

Patient: 73 year old male, weighing 68.0 kg (149.7 pounds)

Adverse reactions / side effects: Weight Increased, Humerus Fracture, Fall

Suspect drug(s):
Actos
    Dosage: see image
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2001-05-22

Actos
    Dosage: see image
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2001-06-21

Actos
    Dosage: see image
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2002-02-15

Other drugs received by patient: Metformin HCL; Glipizide; Altace; Protonix; Calcium (Calcium); Vitamin D; Vitamin E; Glucotrol XL; Zetia

Adverse event in 45 year old male receiving Actos (Pioglitazone)

Reported by a physician from United States on 2007-05-23

Patient: 45 year old male, weighing 128.4 kg (282.4 pounds)

Adverse reactions / side effects: Weight Increased, Pain, Hemiplegia, Multiple Sclerosis, Fall

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Glucophage; Glyburide; Tricor; Accupril; Amitriptyline HCL; Protonix; Baclofen (Baclofen ) (10 Milligram); Seroquel; Copaxone

Adverse event in 51 year old male receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from Japan on 2007-05-21

Patient: 51 year old male

Adverse reactions / side effects: Weight Increased, Oedema, Cardiomegaly, Pericardial Effusion

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Glufast (Mitiglinide Calcium Hydrate); Metformin Hydrochloride; Glucobay

Adverse event in 59 year old male receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from Australia on 2007-05-14

Patient: 59 year old male

Adverse reactions / side effects: Weight Increased, Dysgeusia, Acute Myocardial Infarction

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Insulin; Metformin HCL

Adverse event in 62 year old female receiving Actos (Pioglitazone)

Reported by a consumer/non-health professional from United States on 2007-05-04

Patient: 62 year old female, weighing 120.2 kg (264.4 pounds)

Adverse reactions / side effects: Weight Increased, Pain in Extremity, Fibromyalgia, Oedema Peripheral, Abdominal Distension, Pulmonary Embolism, Exostosis

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos
    Dosage: see image
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2003-01-01
    End date: 2004-01-01

Actos
    Dosage: see image
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2004-01-01
    End date: 2006-06-01

Actos
    Dosage: see image
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2006-06-01
    End date: 2006-09-01

Other drugs received by patient: Pravachol (Pravastatin Sodium) (20 Milligram); Vasotec; Prozac (Fluoxetine Hydrochloride) (10 Milligram); Coumadin

Adverse event in 59 year old male receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from Australia on 2007-05-03

Patient: 59 year old male

Adverse reactions / side effects: Weight Increased, Dysgeusia, Acute Myocardial Infarction

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Insulin; Metformin HCL

Adverse event in 72 year old female receiving Actos (Pioglitazone)

Reported by a health professional (non-physician/pharmacist) from United States on 2007-05-01

Patient: 72 year old female, weighing 64.4 kg (141.7 pounds)

Adverse reactions / side effects: Weight Increased, Glycosylated Haemoglobin Increased, Retinal Oedema

Suspect drug(s):
Actos
    Dosage: 30 mg, 1 in 1 d, per oral
    Administration route: Oral
    Indication: Diabetes Mellitus non-Insulin-Dependent
    Start date: 2002-12-22

Actos

Other drugs received by patient: Armour Thyroid (Thyroid) (60 Milligram)

Adverse event in 63 year old female receiving Actos (Pioglitazone)

Reported by a consumer/non-health professional from United States on 2007-04-30

Patient: 63 year old female

Adverse reactions / side effects: Weight Increased, Anaemia, Oedema Peripheral, Myocardial Infarction

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Glucophage; Micronase; Metoprolol Tartrate; Januvia (Drug Used IN Diabetes); Nexium

Adverse event in 59 year old male receiving Actos (Pioglitazone)

Reported by a individual with unspecified qualification from Australia on 2007-04-27

Patient: 59 year old male

Adverse reactions / side effects: Weight Increased, Dysgeusia, Acute Myocardial Infarction

Adverse event resulted in: hospitalization

Suspect drug(s):
Actos (Pioglitazone)

Other drugs received by patient: Insulin; Metformin HCL