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This is an index of reports of adverse events (side effects, adverse reactions, etc.) related to Abraxane (Paclitaxel). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the side effect / adverse reaction. Or scroll down to view a sample of recent reports further on this page.
Our database includes reports from Jan 2007 to Dec 2007. The information is not vetted and should not be cosidered as verified clinical evidence.
All cases (61)
Cases resulting in a serious event (59)
Cases resulting in death (5)
Cases resulting in life threatening events (10)
Cases resulting in hospitalization (40)
Cases resulting in disability (13)
Cases resulting in other serious reactions (11)
Below is a sample of reports where side effects / adverse reactions may be related to Abraxane (Paclitaxel). For a complete list and/or a specific selection of reports, please use the links in the index above.
Adverse event in 78 year old female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-10-24
Patient: 78 year old female, weighing 51.0 kg (112.2 pounds)
Adverse reactions / side effects: Metastases TO Meninges, Inappropriate Antidiuretic Hormone Secretion
Adverse event resulted in: hospitalization, disablity
Suspect drug(s):
Abraxane (Paclitaxel)
Other drugs received by patient: Multivitamin (Vitamins); Oscal (Calcium Carbonate); Aspirin; Lisinopril; Coreg; Miralax
Adverse event in 55 year old female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-10-24
Patient: 55 year old female, weighing 52.0 kg (114.4 pounds)
Adverse reactions / side effects: Inappropriate Antidiuretic Hormone Secretion
Adverse event resulted in: death, life threatening event, hospitalization, disablity
Suspect drug(s):
Abraxane (Paclitaxel)
Other drugs received by patient: Avastin; MVI (Multivitamins); Prilosec; Herbs; Calcium + Vitamin D (Calcium with Vitamin D); Ascorbic Acid; Oxycodone HCL
Adverse event in 48 year old female receiving Abraxane (Paclitaxel)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-23
Patient: 48 year old female
Adverse reactions / side effects: Febrile Neutropenia
Adverse event resulted in: hospitalization
Suspect drug(s):
Carboplatin
Dosage: initial dose 993mg
Indication: Neoplasm Malignant
Start date: 2007-09-27
End date: 2007-09-27
Abraxane
Dosage: initial dose 150mg,reduced to 64 mg/m2 after event and restarted on 15-oct-07 with 80mg/m2
Indication: Neoplasm Malignant
Start date: 2007-09-27
End date: 2007-09-27
Other drugs received by patient: Advair Diskus 100 / 50; Albuterol; Alprazolam; Alrex; Colace; Compazine; Compazine; Esomeprazole; Neupogen; Lescol XL; Loratadine; Metoclopramide; Montelukast Sodium; Ondansetron; Levofloxacin; Metronidazole
Adverse event in 49 year old female receiving Abraxane (Paclitaxel)
Reported by a pharmacist from United States on 2007-10-18
Patient: 49 year old female, weighing 86.0 kg (189.2 pounds)
Adverse reactions / side effects: Rash Maculo-Papular
Suspect drug(s):
Abraxane
Dosage: 286mg weekly iv
Indication: Metastatic Malignant Melanoma
Start date: 2007-10-03
Abraxane
Dosage: 286mg weekly iv
Indication: Metastatic Malignant Melanoma
Start date: 2007-10-10
Adverse event in 40 year old female receiving Abraxane (Paclitaxel)
Reported by a pharmacist from United States on 2007-10-18
Patient: 40 year old female, weighing 109.0 kg (239.8 pounds)
Adverse reactions / side effects: Drug Hypersensitivity, Type IV Hypersensitivity Reaction, Erythema Multiforme
Suspect drug(s):
Abraxane
Dosage: 210 mg once iv
Indication: Metastatic Malignant Melanoma
Start date: 2007-09-10
Abraxane
Dosage: 210 mg once iv
Indication: Metastatic Malignant Melanoma
Start date: 2007-09-12
Abraxane
Dosage: 210 mg once iv
Indication: Metastatic Malignant Melanoma
Start date: 2007-09-19
Adverse event in female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-10-10
Patient: female
Adverse reactions / side effects: Gastric Ulcer
Adverse event resulted in: hospitalization
Suspect drug(s):
Bevacizumab
Dosage: 1070 mg, unk
Indication: Breast Cancer Metastatic
Start date: 2007-05-04
Abraxane
Dosage: 260 mg, unk
Indication: Breast Cancer Metastatic
Start date: 2007-05-04
Abraxane
Dosage: 180 mg, unk
Other drugs received by patient: Motrin; Aspirin; Pepcid; Preparation H; Lisinopril; Cipro; Flagyl
Adverse event in 65 year old female receiving Abraxane (Paclitaxel)
Reported by a consumer/non-health professional from United States on 2007-10-10
Patient: 65 year old female, weighing 49.9 kg (109.8 pounds)
Adverse reactions / side effects: Refusal of Treatment by Patient, Vomiting, Diarrhoea, Gastrointestinal Disorder, Haematemesis
Adverse event resulted in: hospitalization
Suspect drug(s):
Abraxane (Paclitaxel)
Adverse event in 55 year old female receiving Abraxane (Paclitaxel)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-02
Patient: 55 year old female
Adverse reactions / side effects: Chills, Pyrexia, Eye Infection, Jugular Vein Thrombosis, Stevens-Johnson Syndrome, Blister, Cough, Vomiting, Rash Generalised, Stomatitis, Nausea, Anaemia, Hypotension, Staphylococcal Sepsis, Convulsion, Diarrhoea, Staphylococcal Infection
Adverse event resulted in: hospitalization
Suspect drug(s):
Nexavar
Dosage: total daily dose: 400 mg unit dose: 200 mg
Administration route: Oral
Indication: Metastatic Malignant Melanoma
Start date: 2006-09-01
End date: 2006-11-07
Nexavar
Dosage: total daily dose: 800 mg unit dose: 200 mg
Administration route: Oral
Start date: 2006-08-14
End date: 2006-09-01
Pyridoxine (Vitamin B6)
Indication: Drug USE FOR Unknown Indication
Vancomycin
Indication: Staphylococcal Infection
Abraxane
Indication: Malignant Melanoma
Carboplatin
Indication: Malignant Melanoma
Other drugs received by patient: Coumadin; Atenolol; Hydroxizine
Adverse event in 68 year old female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-07-31
Patient: 68 year old female
Adverse reactions / side effects: Malignant Neoplasm Progression, Pleural Effusion, Oedema
Adverse event resulted in: hospitalization
Suspect drug(s):
Abraxane (Paclitaxel)
Other drugs received by patient: Camptosar
Adverse event in female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-07-27
Patient: female
Adverse reactions / side effects: Pain in Extremity, Chest Pain, Hypothyroidism
Adverse event resulted in: hospitalization
Suspect drug(s):
Bevacizumab
Indication: Breast Cancer
Start date: 2006-11-08
Abraxane
Indication: Breast Cancer
Start date: 2006-11-08
Cyclophosphamide
Indication: Breast Cancer
Start date: 2006-11-08
Doxorubicin HCL
Indication: Breast Cancer
Start date: 2006-11-08
Other drugs received by patient: Aprepitant; Bisoprolol Fumarate; Dexamethasone 0.5mg TAB; Docusate; Lorazepam; Pegfilgrastim
Adverse event in 62 year old female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-07-26
Patient: 62 year old female, weighing 63.5 kg (139.7 pounds)
Adverse reactions / side effects: Hepatic Cirrhosis
Adverse event resulted in: disablity
Suspect drug(s):
Capecitabine
Dosage: dose reported as 3250 (units and frequency not reported).
Start date: 2006-01-05
Capecitabine
Dosage: 2500mg is a reduced dose from 3250 (units not reported)
Capecitabine
Dosage: 2000mg is a dose reduction from 2500mg.
End date: 2006-11-01
Bevacizumab
Start date: 2006-11-15
End date: 2007-04-03
Bevacizumab
Dosage: frequency not reported.
Start date: 2006-01-05
End date: 2006-11-01
Abraxane
Dosage: dose reported as 174 (units not reported, frequency and route not reported). drug reported as abra+
Start date: 2006-12-06
End date: 2007-04-03
Docetaxel
Dosage: dose reported as 139 (units not reported, frequency and route not reported)
Start date: 2006-11-15
End date: 2006-12-06
Adverse event in 76 year old female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-07-25
Patient: 76 year old female, weighing 77.3 kg (170.1 pounds)
Adverse reactions / side effects: Dehydration, Diverticulitis, Febrile Neutropenia
Adverse event resulted in: hospitalization
Suspect drug(s):
Lapatinib
Dosage: 1000mg per day
Administration route: Oral
Start date: 2006-10-20
End date: 2007-02-08
Trastuzumab
Start date: 2006-10-20
Abraxane
Dosage: 100mgm2 weekly
Start date: 2007-02-08
End date: 2007-02-15
Adverse event in 56 year old female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-07-25
Patient: 56 year old female, weighing 65.0 kg (143.0 pounds)
Adverse reactions / side effects: Metastases TO Liver, Hepatic Vein Thrombosis, Abdominal Distension
Adverse event resulted in: death
Suspect drug(s):
Abraxane
Dosage: intravenous
Indication: Breast Cancer Metastatic
Start date: 2006-09-01
End date: 2007-05-08
Arimidex
Indication: Breast Cancer Metastatic
Other drugs received by patient: Gemzar
Adverse event in female receiving Abraxane (Paclitaxel)
Reported by a pharmacist from United States on 2007-07-23
Patient: female, weighing 113.9 kg (250.5 pounds)
Adverse reactions / side effects: Neuropathy Peripheral, Nail Disorder, Adverse Event, Feeling of Body Temperature Change, Sensitivity of Teeth
Suspect drug(s):
Abraxane
Dosage: 220 mg 3 wks on, 1 wk off iv
Indication: Breast Cancer Metastatic
Start date: 2006-11-29
End date: 2007-07-01
Aranesp
Dosage: 100 mg qweek sq
Indication: Anaemia
Start date: 2005-11-18
End date: 2007-07-01
Aranesp
Dosage: 100 mg qweek sq
Indication: Chemotherapy
Start date: 2005-11-18
End date: 2007-07-01
Adverse event in 53 year old female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-07-17
Patient: 53 year old female, weighing 62.1 kg (136.7 pounds)
Adverse reactions / side effects: Clostridium Difficile Toxin Test Positive, Diverticulitis, Sigmoiditis, Abscess Intestinal, Lung Consolidation, Sepsis, Pseudomembranous Colitis, Pleural Effusion, Platelet Count Decreased, Escherichia Infection, Enterocolitis Infectious, Candidiasis, Haemoglobin Increased
Adverse event resulted in: hospitalization
Suspect drug(s):
Abraxane
Dosage: see image
Indication: Breast Cancer
Start date: 2007-01-03
End date: 2007-02-01
Gemcitabine
Dosage: see image
Indication: Breast Cancer
Start date: 2007-01-03
End date: 2007-02-01
Epirubicin
Dosage: see image
Indication: Breast Cancer
Start date: 2007-01-03
End date: 2007-02-01
Neulasta
Dosage: see image
Indication: Colony Stimulating Factor Prophylaxis
Start date: 2007-01-04
End date: 2007-02-01
Other drugs received by patient: Emend (Antiemetics and Antinauseants); Compazine; Darvocet; Miralax Powder (Macrogol); Dicyclomine; Fiber
Adverse event in female receiving Abraxane (Paclitaxel)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-06-28
Patient: female
Adverse reactions / side effects: Facial Palsy
Adverse event resulted in: disablity
Suspect drug(s):
Abraxane (Paclitaxel)
Other drugs received by patient: Nexium; Aromasin; Xeloda; Lexapro; Potassium (Potassium); Colace Caps (Docusate Sodium); Duragesic-100; Percocet; Lunesta; Compazine (Prochlorperazine Maleate)
Adverse event in 47 year old female receiving Abraxane (Paclitaxel)
Reported by a physician from United States on 2007-06-27
Patient: 47 year old female, weighing 50.3 kg (110.7 pounds)
Adverse reactions / side effects: Tumour Necrosis, Hepatic Fibrosis, Metastases TO Liver, Cholestasis, Coma Hepatic, Hepatic Failure
Adverse event resulted in: death, hospitalization
Suspect drug(s):
Capecitabine
Start date: 2006-01-17
Capecitabine
Capecitabine
Bevacizumab
End date: 2007-04-12
Blinded Bevacizumab
Start date: 2006-01-17
Abraxane
Dosage: frequency and route not reported. drug reported as abraxane (paclitaxel protein-bound/albumin).
Start date: 2006-07-06
Adverse event in 63 year old female receiving Abraxane (Paclitaxel)
Reported by a individual with unspecified qualification from United States on 2007-06-25
Patient: 63 year old female
Adverse reactions / side effects: Aphthous Stomatitis, Pneumonia, Nausea, Anaemia, Toothache, Headache, Sinusitis
Adverse event resulted in: hospitalization
Suspect drug(s):
Abraxane (Paclitaxel)
Other drugs received by patient: Acyclovir; Coumadin; Tylenol; Ibuprofen; Omeprazole; Vitamin B6
Adverse event in 70 year old female receiving Abraxane (Paclitaxel)
Reported by a consumer/non-health professional from United States on 2007-06-18
Patient: 70 year old female
Adverse reactions / side effects: Neuropathy Peripheral, Peroneal Nerve Palsy, Fluid Retention
Adverse event resulted in: disablity
Suspect drug(s):
Abraxane (Paclitaxel)
Adverse event in 37 year old female receiving Abraxane (Paclitaxel)
Reported by a consumer/non-health professional from United States on 2007-06-18
Patient: 37 year old female
Adverse reactions / side effects: Skin Discolouration, Joint Swelling, Nail Discolouration, Pain in Extremity, Oedema Peripheral
Adverse event resulted in: hospitalization
Suspect drug(s):
Abraxane (Paclitaxel)
Other drugs received by patient: Morphine Sulfate
Adverse event in 49 year old female receiving Abraxane (Paclitaxel)
Reported by a pharmacist from United States on 2007-06-14
Patient: 49 year old female, weighing 74.8 kg (164.7 pounds)
Adverse reactions / side effects: Cellulitis, Tongue Ulceration, Febrile Neutropenia, LIP Ulceration, Skin Ulcer, Oedema Peripheral, Neutropenia, Lymphoedema
Suspect drug(s):
Avastin
Dosage: iv (2nd cycle)
Indication: Breast Cancer Metastatic
Abraxane
Dosage: iv (2nd cycle)
Indication: Breast Cancer Metastatic
Other drugs received by patient: Hydromorphone HCL; Ativan; Diflucan; Rocephin; Famvir
Adverse event in 68 year old female receiving Abraxane (Paclitaxel)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-06-13
Patient: 68 year old female, weighing 110.2 kg (242.5 pounds)
Adverse reactions / side effects: Dehydration, Hypotension, Dizziness
Adverse event resulted in: hospitalization
Suspect drug(s):
Xeloda
Dosage: 650mg/m2/bid14days/oral
Administration route: Oral
Indication: Breast Cancer
Start date: 2007-05-25
End date: 2007-06-08
Abraxane
Dosage: 533mg/m2/q 21 days/iv
Indication: Breast Cancer
Start date: 2007-05-25
End date: 2007-05-25
Other drugs received by patient: Furosemide; Lantus; Lisinopril; Metformin HCL; OS-CAL; Dynacirc CR
Adverse event in 73 year old female receiving Abraxane (Paclitaxel)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-06-12
Patient: 73 year old female
Adverse reactions / side effects: Incontinence, Loss of Consciousness
Adverse event resulted in: hospitalization
Suspect drug(s):
Abraxane (Paclitaxel)
Other drugs received by patient: Decadron; Benadryl; Anzemet; Aranesp; Zometa
Adverse event in 53 year old male receiving Abraxane (Paclitaxel)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-06-11
Patient: 53 year old male
Adverse reactions / side effects: Angina Unstable
Adverse event resulted in: hospitalization
Suspect drug(s):
Carboplatin
Indication: non-Small Cell Lung Cancer
Start date: 2005-07-20
End date: 2005-07-20
Abraxane
Indication: non-Small Cell Lung Cancer
Start date: 2005-07-20
End date: 2005-07-20
Other drugs received by patient: Acetylsalicylic Acid SRT; Fosinopril + Hctz; Carbamazepine; Bisoprolol Fumarate; Isosorbide Dinitrate
Adverse event in 63 year old female receiving Abraxane (Paclitaxel)
Reported by a health professional (non-physician/pharmacist) from United States on 2007-05-25
Patient: 63 year old female, weighing 71.7 kg (157.7 pounds)
Adverse reactions / side effects: Deep Vein Thrombosis
Adverse event resulted in: hospitalization
Suspect drug(s):
Abraxane
Dosage: 260mg/m2/q 21 days/iv
Indication: Breast Cancer
Start date: 2007-02-02
End date: 2007-02-18
Xeloda
Dosage: 825mg/m2/bid14days/oral
Administration route: Oral
Indication: Breast Cancer
Start date: 2007-02-23
End date: 2007-03-08
Other drugs received by patient: Synthroid
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