Brands, Medical Use, Clinical Data
- Enzyme Inhibitors
- Neuraminidase Inhibitors
Brands / Synonyms
GANA; GNA; MODIFIED SIALIC ACID; Relenza; See Remark 8; Zanamavir
For the prevention and treatment of influenza
Zanamivir, an antiviral agent, is a neuraminidase inhibitor indicated for treatment of uncomplicated acute illness due to influenza A and B virus in adults and pediatric patients 7 years and older who have been symptomatic for no more than 2 days.
Mechanism of Action
The proposed mechanism of action of zanamivir is via inhibition of influenza virus neuraminidase with the possibility of alteration of virus particle aggregation and release.
4% to 17% following an orally inhaled dose
Biotrnasformation / Drug Metabolism
RELENZA is contraindicated in patients with a known hypersensitivity to any component of the
No clinically significant pharmacokinetic drug interactions are predicted based on data from in vitro