Chemisty and Biological Activity
Chemical Formula
C18H22N2S
Chemical Name
N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine
Chemical Structure
Molecular Weight
298.447 g/mol
Physical State
Solid
Melting Point
68 oC
Water Solubility
0.942 mg/L
Isoelectric Point
9.05
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
Name | Histamine H1 receptor | Gene Name | HRH1 | Synonyms | None | Specific Function | In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system |
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