Chemisty and Biological Activity
Chemical Formula
C8H8Cl3N3O4S2
Chemical Name
3-chloro-9-(dichloromethyl)-7,7-dioxo-7$l^{6}-thia-8,10- diazabicyclo[4.4.0]deca-1,3,5-triene-4-sulfonamide
Chemical Structure
Molecular Weight
380.657 g/mol
Physical State
Solid
Melting Point
Not Available
Water Solubility
Not Available
Isoelectric Point
8.6
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Na+/K+/2Cl- co-transporter | | Gene Name | SLC12A1 | | Synonyms | Solute carrier family 12, member 1; Bumetanide-sensitive sodium-; potassium-chloride cotransporter 2; Kidney-specific Na-K-Cl symporter | | General Function | Inorganic ion transport and metabolism | | Specific Function | Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume |
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