Brands, Medical Use, Clinical Data
- Anti-inflammatory Agents
- Adrenergic Agents
- Metered-dose (aerosol)
Brands / Synonyms
Adcortyl; Aristocort; Aristocort A; Aristocort Tablets; Aristogel; Aristospan; Azmacort; Azmacort Inhalation; Celeste; Cinolone; Cinolone-T; Delphicort; Fluoxiprednisolone; Fluoxyprednisolone; Flutex; Kenacort; Kenacort-A; Kenacort-Ag; Kenalog; Kenalog in Orabase; Kenalog-10; Kenalog-40; Kenalog-H; Ledercort; Mycolog-II; Nasacort; Nasacort AQ; Nasacort HFA; Omcilon; Omicilon; Oracort; Oralone; Orion; Polcortolon; Rodinolone; Sk-Triamcinolone; Tiamcinolonum [Inn-Latin]; Tri-Nasal; Triacet; Triacort; Triam-Tablinen; Triamcet; Triamcinalone; Triamcinlon; Triamcinolon; Triamcinolona [Inn-Spanish]; Triamcinolone Acetonide; Triamcinolone Acetonide in Absorbase; Triamcinolone Diacetate; Triamcinolone [Usan:Ban:Inn:Jan]; Triamcinolonum [Inn]; Triatex; Tricortale; Triderm; Trymex; Vetalog; Volon
For the treatment of perennial and seasonal allergic rhinitis.
Triamcinolone and its derivatives are synthetic glucocorticoids that are used for their antiinflammatory or immunosuppressive properties.
Mechanism of Action
The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding.
Rapid absorption following oral administration
LD50=>500mg/kg (in rats)
Biotrnasformation / Drug Metabolism
Azmacort Inhalation Aerosol is contraindicated in the primary treatment of status asthmaticus or
other acute episodes of asthma where intensive measures are required.
Hypersensitivity to triamcinolone acetonide or any of the other ingredients in this preparation contraindicates