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Active ingredient: Triamcinolone - Brands, Medical Use, Clinical Data

Brands, Medical Use, Clinical Data

Drug Category

  • Glucocorticoids
  • Anti-inflammatory Agents
  • Adrenergic Agents

Dosage Forms

  • Cream
  • Liquid
  • Metered-dose (aerosol)
  • Ointment
  • Paste
  • Suspension
  • Syrup
  • Tablet

Brands / Synonyms

Adcortyl; Aristocort; Aristocort A; Aristocort Tablets; Aristogel; Aristospan; Azmacort; Azmacort Inhalation; Celeste; Cinolone; Cinolone-T; Delphicort; Fluoxiprednisolone; Fluoxyprednisolone; Flutex; Kenacort; Kenacort-A; Kenacort-Ag; Kenalog; Kenalog in Orabase; Kenalog-10; Kenalog-40; Kenalog-H; Ledercort; Mycolog-II; Nasacort; Nasacort AQ; Nasacort HFA; Omcilon; Omicilon; Oracort; Oralone; Orion; Polcortolon; Rodinolone; Sk-Triamcinolone; Tiamcinolonum [Inn-Latin]; Tri-Nasal; Triacet; Triacort; Triam-Tablinen; Triamcet; Triamcinalone; Triamcinlon; Triamcinolon; Triamcinolona [Inn-Spanish]; Triamcinolone Acetonide; Triamcinolone Acetonide in Absorbase; Triamcinolone Diacetate; Triamcinolone [Usan:Ban:Inn:Jan]; Triamcinolonum [Inn]; Triatex; Tricortale; Triderm; Trymex; Vetalog; Volon

Indications

For the treatment of perennial and seasonal allergic rhinitis.

Pharmacology

Triamcinolone and its derivatives are synthetic glucocorticoids that are used for their antiinflammatory or immunosuppressive properties.

Mechanism of Action

The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding.

Absorption

Rapid absorption following oral administration

Toxicity

LD50=>500mg/kg (in rats)

Biotrnasformation / Drug Metabolism

Not Available

Contraindications

Azmacort Inhalation Aerosol is contraindicated in the primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures are required.

Hypersensitivity to triamcinolone acetonide or any of the other ingredients in this preparation contraindicates its use.

Drug Interactions

Not Available

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