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Active ingredient: Treprostinil - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C23H34O5

Chemical Name

Not Available

Chemical Structure

Molecular Weight

390.513 g/mol

Physical State

Solid

Melting Point

Not Available

Water Solubility

Insoluble at 25°C

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameSmall inducible cytokine A23 precursor
Gene NameCCL23
SynonymsCCL23; Macrophage inflammatory protein 3; MIP-3; Myeloid progenitor inhibitory factor- 1; MPIF-1; CK-beta-8; CKB-8
Specific FunctionShows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1

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