Brands, Medical Use, Clinical Data
- 100-mg tablets and 200-mg capsules for oral administration
Brands / Synonyms
Anturan; Anturane; Anturanil; Anturano; Anturen; Anturidin; Apo-Sulfinpyrazone; Diphenylpyrazone; Enturan; Enturen; Novopyrazone; Sulfinpyrazine; Sulfinpyrazon; Sulfoxyphenylpyrazolidine; Sulphinpyrazone; Usaf Ge-13
For the treatment of gout and gouty arthritis.
Sulfinpyrazone's pharmacologic activity is the potentiation of the urinary excretion of uric acid. It is useful for reducing the blood urate levels in patients with chronic tophaceous gout and acute intermittent gout, and for promoting the resorption of tophi.
Mechanism of Action
Symptoms of overdose include nausea, vomiting, diarrhea, epigastric pain, ataxia, labored respiration, convulsions, coma. Possible symptoms, seen after overdosage with other pyrazolone derivatives: anemia, jaundice, and ulceration.
Biotrnasformation / Drug Metabolism
Patients with an active peptic ulcer or symptoms of gastrointestinal inflammation or ulceration should not receive
The drug is contraindicated in patients with a history or the presence of:
1. Hypersensitivity to phenylbutazone or other pyrazoles
2. Blood dyacrasias
No information provided.