Chemisty and Biological Activity
Chemical Formula
C21H39N7O12
Chemical Name
5-(2,4-diguanidino-3,5,6-trihydroxy-cyclohexoxy)-4-[4,5-dihydroxy-6- (hydroxymethyl)-3-methylamino-tetrahydropyran-2-yl]oxy-3-hydroxy-2-methyl- tetrahydrofuran-3-carbaldehyde
Chemical Structure
Molecular Weight
581.574 g/mol
Physical State
Solid
Melting Point
Not Available
Water Solubility
Not Available
Isoelectric Point
Not Available
Organisms Affected
Enteric bacteria and other eubacteria
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
Name | 30S ribosomal protein S12 | Gene Name | rpsL | Synonyms | 30S ribosomal protein S12 | General Function | Translation, ribosomal structure and biogenesis | Specific Function | Cryo-EM studies suggest that S12 contacts the EF-Tu bound tRNA in the A-site during codon-recognition. This contact is most likely broken as the aminoacyl-tRNA moves into the peptidyl transferase center in the 50S subunit |
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