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Active ingredient: Spironolactone - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

Not Available

Chemical Structure

Molecular Weight

416.574 g/mol

Physical State


Melting Point

134.5 oC

Water Solubility

Practically insoluble (22 mg/L)

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameType-1 angiotensin II Receptor (AT1)
Gene NameAGTR1
SynonymsType-1 angiotensin II receptor; AT1; AT1AR
Specific FunctionReceptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system

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