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Active ingredient: Propranolol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C16H21NO2

Chemical Name

1-(1-methylethylamino)-3-naphthalen-1-yloxy-propan-2-ol

Chemical Structure

Molecular Weight

259.343 g/mol

Physical State

Solid

Melting Point

163-164oC

Water Solubility

0.070 mg/mL (HCl salt)

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP1A2

Primary Drug Target
NameBeta-1 Adrenergic Receptor
Gene NameADRB1
SynonymsBeta-1 adrenoceptor; Beta-1 adrenoreceptor
General FunctionReceptor activity and cell communication
Specific FunctionBeta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximatively equal affinity

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