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Active ingredient: Prochlorperazine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C20H24ClN3S

Chemical Name

2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine

Chemical Structure

Molecular Weight

373.943 g/mol

Physical State

Solid

Melting Point

228oC

Water Solubility

Very slightly soluble

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2D6; CYP3A4

Primary Drug Target
NameD(2) Dopamine Receptor
Gene NameDRD2
SynonymsD(2 dopamine receptor; Dopamine D2 receptor
General FunctionReceptor activity and cell communication
Specific FunctionThis is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase

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