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Active ingredient: Pindolol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C14H20N2O2

Chemical Name

1-(1H-indol-4-yloxy)-3-(1-methylethylamino)propan-2-ol

Chemical Structure

Molecular Weight

248.321 g/mol

Physical State

Solid

Melting Point

167-171 oC

Water Solubility

7880 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2D6

Primary Drug Target
NameBeta-1 Adrenergic Receptor
Gene NameADRB1
SynonymsBeta-1 adrenergic receptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor
General FunctionReceptor activity and cell communication
Specific FunctionBeta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximatively equal affinity

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