Chemisty and Biological Activity
Chemical Formula
C28H29F2N3O
Chemical Name
1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1,3-dihydrobenzoimidazol-2- one
Chemical Structure
Molecular Weight
461.546 g/mol
Physical State
Solid
Melting Point
214-218 oC
Water Solubility
10 mg/L
Isoelectric Point
8.63
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
CYP3A4; CYP1A2
Primary Drug Target
| Name | D(2) dopamine receptor | | Gene Name | DRD2 | | Synonyms | Dopamine D2 receptor | | General Function | Signal transduction and cell communication | | Specific Function | This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase |
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