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Active ingredient: Phenelzine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name


Chemical Structure

Molecular Weight

136.194 g/mol

Physical State


Melting Point

< 25 oC

Water Solubility

29.1 g/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameMonoamine oxidase A (MAO-A)
Gene NameMAOA
SynonymsAmine oxidase [flavin-containing] A; EC; Monoamine oxidase type A; MAO-A
General FunctionAmino acid transport and metabolism
Specific FunctionCatalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAO-A preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
Pathwaymap00260 Glycine, serine and threonine metabolism map00330 Arginine and proline metabolism map00340 Histidine metabolism map00350 Tyrosine metabolism map00360 Phenylalanine metabolism map00380 Tryptophan metabolism
ReactionRCH2NH2 + H2O + O2 = RCHO + ammonia + H2O2

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