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Active ingredient: Pentoxifylline - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C13H18N4O3

Chemical Name

3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydropurine-2,6-dione

Chemical Structure

Molecular Weight

278.307 g/mol

Physical State

Solid

Melting Point

105oC

Water Solubility

77 mg/mL

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NamecAMP Phosphodiesterase
Gene NamePDE4B
SynonymscAMP-specific 3',5'-cyclic phosphodiesterase 4B; EC 3.1.4.17; DPDE4; PDE32
Specific FunctionMay be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Pathwaymap00230 Purine metabolism
Reactionnucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate

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