Basic Profile / Key Facts
Drug Category
- Central Nervous System Stimulants
Dosage Forms
Indications
For treatment of Attention Deficit Hyperactivity Disorder (ADHD)
Pharmacology
Pemoline belongs to the group of medicines called central nervous system (CNS) stimulants. It is used to treat attention deficit hyperactivity disorder (ADHD). Pemoline stimulates the brain, probably by affecting neurotransmitters, the chemicals in the brain that nerves use to communicate with each other.
Mechanism of Action
Not Available
Absorption
Pemoline is rapidly absorbed from the gastrointestinal tract
Toxicity
Side effects include insomnia, anorexia, stomach ache, skin rashes, increased irritability, mild depression, nausea, dizziness, headache, drowsiness, and hallucinations
Biotrnasformation / Drug Metabolism
Hepatic
Contraindications
CYLERT (pemoline) is contraindicated in patients with known hypersensitivity or idiosyncrasy to the drug. CYLERT
should not be administered to patients with impaired hepatic function .
Drug Interactions
The interaction of CYLERT (pemoline) with other drugs has not been studied in humans. Patients who are receiving
CYLERT concurrently with other drugs, especially drugs with CNS activity, should be monitored carefully.
Decreased seizure threshold has been reported in patients receiving CYLERT concomitantly with antiepileptic
medications.
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