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Active ingredient: Ondansetron - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C18H19N3O

Chemical Name

9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydrocarbazol-4- one

Chemical Structure

Molecular Weight

293.363 g/mol

Physical State

Solid

Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP3A4; CYP1A2; CYP2D6

Primary Drug Target
Name5-HT-3 Receptor
Gene NameHTR3A
Synonyms5-hydroxytryptamine 3 receptor precursor; 5-HT-3; Serotonin-gated ion channel receptor; 5-HT3R
Specific FunctionThis is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel

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