Chemisty and Biological Activity
Chemical Formula
C49H66N10O10S2.2C2H4O2
Chemical Name
Octreotide acetate
Chemical Structure
Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxy-methyl) propyl]-, cyclic (2?7)-disulfide; [R-(R*,R*)]
Molecular Weight
1138.4822
Physical State
Liquid
Melting Point
Not Available
Water Solubility
Not Available
Isoelectric Point
Not Available
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Somatostatin receptor type 2 | | Gene Name | SSTR2 | | Synonyms | Somatostatin receptor type 2; SS2R; SRIF-1 | | Specific Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels |
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