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Active ingredient: Norethindrone - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C20H26O2

Chemical Name

(8R,9S,10R,13S,14S,17S)-17-ethynyl-17-hydroxy-13-methyl- 1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

Chemical Structure

Molecular Weight

298.419 g/mol

Physical State

Solid

Melting Point

203.5 oC

Water Solubility

7.04 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP3A4

Primary Drug Target
NameProgesterone Receptor
Gene NamePGR
SynonymsProgesterone receptor; PR
Specific FunctionThe steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues

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