Active ingredient: Naloxone - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C19H21NO4

Chemical Name

Not Available

Chemical Structure

Molecular Weight

327.374 g/mol

Physical State

Solid

Melting Point

200 - 205 oC

Water Solubility

Soluble

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target

Name	Opioid mu Receptor (OP3)
Gene Name	OPRM1
Synonyms	Mu-type opioid receptor; MOR-1
Specific Function	Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin.