Active ingredient: Naftifine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C21H21N

Chemical Name

N-methyl-N-(naphthalen-1-ylmethyl)-3-phenyl-prop-2-en-1-amine

Chemical Structure

Molecular Weight

287.398 g/mol

Physical State

Solid

Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Yeast and other fungi

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target

Name	Squalene Epoxidase
Gene Name	SQLE
Synonyms	Squalene monooxygenase; EC 1.14.99.7; Squalene epoxidase; SE
General Function	Coenzyme transport and metabolism
Specific Function	Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway
Pathway	map00100 Biosynthesis of steroids map00900 Terpenoid biosynthesis
Reaction	squalene + AH2 + O2 = (S)-squalene-2,3-epoxide + A + H2O