Chemisty and Biological Activity
Chemical Formula
C17H19N3
Chemical Name
1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3- c][2]benzazepine
Chemical Structure
Molecular Weight
265.353 g/mol
Physical State
Solid
Melting Point
114-116oC
Water Solubility
Slight
Isoelectric Point
Not Available
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
CYP1A2; CYP3A4; CYP2D6
Primary Drug Target
Name | 5-hydroxytryptamine 2A receptor | Gene Name | HTR2A | Synonyms | 5-HT-2A; Serotonin receptor 2A; 5- HT-2 | Specific Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production |
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