Active ingredient: Metoprolol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C15H25NO3

Chemical Name

1-[4-(2-methoxyethyl)phenoxy]-3-(1-methylethylamino)propan-2-ol

Chemical Structure

Molecular Weight

267.364 g/mol

Physical State

Solid

Melting Point

120 oC (tartarate salt)

Water Solubility

16.9 mg/mL

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2D6

Primary Drug Target

Name	Beta-1 adrenergic receptor
Gene Name	ADRB1
Synonyms	Beta-1 adrenoceptor; Beta-1 adrenoreceptor
Specific Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximatively equal affinity